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Virusologie umana

Criterii taxonomice

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CRITERII TAXONOMICE

1.caracterele virionului

dimensiuni

form prezena/absena nveliului

structur

simetrie

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CRITERII TAXONOMICE

2. caracterele genomului tip de acid nucleic nr. de catene

structura liniar au circular sensul catenelor pozitiv negativ

ambisens nr. de segmente dimensiunea genomului etc.

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CRITERII TAXONOMICE

3. mod de replicare

strategia de replicare caracterele transcrierii

caracterele translaiei

locul de asamblare locul de maturare etc.

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CRITERII TAXONOMICE

4. caracterele proteinelor virale

numrul proteinelor

secvene de aminoacizi

funciile transcriptaze

reverstranscriptaze

hemaglutinine neuraminidaze

factori de fuziune etc.

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CRITERII TAXONOMICE

5. comportament fa de ageni fizici ichimici

stabilitate la

pH

temperatur

solveni

detergeni

radiaii etc.

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CRITERII TAXONOMICE

6. caractere biologice relaii serologice spectrul de gazd natural

spectrul de gazd experimental bacterii plante animale

vertebrate nevertebrate transmitere etc.

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CRITERII TAXONOMICE

7. patogenitate

tropism

neuro dermo

entero etc.

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CRITERII TAXONOMICE

8. distribuie geografic

encefalita de taiga

febra hemoragic bolivian encefalite West Nile etc

9. criterii filogenetice

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NIVELE TAXONOMICE

SPECIE grupuri de tulpini diferite genetic denumire: virus respirator sinciial uman GEN grupuri de specii cu

caractere comune i cu particulariti proprii ce le difereniaz fa de alte grupuri denumire: sufixul virus: Pneumovirus SUBFAMILIE separat n interiorul unei familii denumire: sufixul virinae: Pneumovirinae

FAMILIE denumire: sufixul viridae: Paramyxoviridae ORDIN denumire: sufixul virales: Mononegavirales, Nidovirales, Caudovirales

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NIVELE TAXONOMICE(exemplu)

familia Herpesviridae,

subfamilia Alphaherpesvirinae,

genul Simplexvirus, specia Virus herpessimplex serotip 2 cvasispecie populaiide virioni derivai dintr-un genom parentaliniial acumulare de mutaii.

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VIRUSURI ARN dublu catenar

fr nveli

REOVIRIDAE ROTAVIRUS

ROTAVIRUS

- gastroenterite

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VIRUSURI ARN monocatenar

sens -

cu nveli PARAMYXOVIRIDAE PARAMYXOVIRINAE RESPIROVIRUS V.

PARAGRIPAL- RUBULAVIRUS V-OREIONULUI- MORBILLIVIRUS V.RUJEOLOS PNEUMOVIRINAE PNEUMOVIRUS - VRS

ARENAVIRIDAE ARENAVIRUS V. CORIOMENINGITEI LIMFOCITARE,

V. LASSA BUNYAVIRIDAE BUNYAVIRUS; HANTAVIRUS; NAIROVIRUS;

PHLEBOVIRUS RHABDOVIRIDAE

LYSSAVIRUS V.RABIC

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VIRUSURI ARN monocatenar

sens +

cu nveli

RETROVIRIDAE ONCOVIRINAE ONCOVIRUS

LENTIVIRINAE LENTIVIRUS HIV, SIV,

SPUMAVIRINAE

CORONAVIRIDAE

CORONAVIRUS CORONAVIRUSURI UMANE TOGAVIRIDAE

ALPHAVIRUS

RUBIVIRUS V.RUBEOLOS

FLAVIVIRIDAE FLAVIVIRUS

ARBOVIRUSURI

- HEPACIVIRUS V.HEPATITEI

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Virus ARN

monocatenar sens + fr nveli

PICORNAVIRIDAE ENTEROVIRUS - V.POLIO;

V.COXSACKIE A,B; V.ECHO HEPATOVIRUS V.HEPATITEI A RHINOVIRUS RHINOVIRUS UMAN APHTOVIRUS V.AFTOS CARDIOVIRUS

V.ENCEFALOMIOCARDITEI

ORFANOVIRUS V.ECHO TIP 22-23

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VIRUSURI AND

dublucatenar

cu nveli

HERPESVIRIDAE

ALPHAHERPESVIRINAE SIMPLEXVIRUS V. HERPES

SIMPLEX 1, 2- VARICELLAVIRUS V. VARICELLA-ZOSTER

BETAHERPESVIRINAE CYTOMEGALOVIRUS V.CITOMEGALIC

- ROSEOLOVIRUS V. HERPETIC UMAN 6 I 7

GAMMAHERPESVIRINAE - RHADINOVIRUS V. HERPETICUMAN 8

HEPADNAVIRIDAE

OTHOHEPADNAVIRUS V. HEPATITEI B

AVIHEPADNAVIRUS

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VI

RU

S

AD

N

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VIRUSURI ADN

dublucatenar

fr nveli

ADENOVIRIDAE

MASTADENOVIRUS ADENOVIRUS

AVIADENOVIRUS

PAPILLOMAVIRIDAE

PAPILLOMAVIRUS V. PAPILOAMELOR UMANE

POLYOMAVIRIDAE

POLYOMAVIRUS

VIRUSURI ADN

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VIRUSURI ADN cu structur complex

POXVIRIDAE ORTHOPOXVIRUS V. VARIOLIC;

V.VACCINIA

PARAPOXVIRUS V. ORF;PSEUDOCOWPOXVIRUSURI

MOLLUSCIPOXVIRUS V. MOLLUSCUMCONTAGIOSUM

LEPOTIPOXVIRUS V. MYXOMULUI