EXPERIENŢA - roald.roUi7a6... · Curriculum Vitae Iacob Maria Speranta © Uniunea Europeană,...

Curriculum Vitae Iacob Maria Speranta

© Uniunea Europeană, 2002-2013 | http://europass.cedefop.europa.eu Pagina 1 / 54

INFORMAŢII

PERSONALE

IACOB MARIA SPERANTA

Adresa (spital): Centrul pentru Boli Digestive si Transplant Hepatic

Institutul Clinic Fundeni

Şoseaua Fundeni nr. 258

022328 Bucureşti, România

+4021 2750500(centrala);

Fax: +40213180447(secretariat);

[email protected]

Sexul F | Data naşterii 08/04/1977 | Naţionalitatea romana

EXPERIENŢA

PROFESIONALĂ

EDUCAŢIE ŞI

FORMARE

2002 Diploma de medic: 545/ 21.03.2002 Seria T Nr. 0028346 Romania

2002 Medic rezident gastroenterologie, Certificat 073/ 12.12.2002

2007 Medic specialist gastroenterologie: OMS 2140/2007

2013 Medic primar gastroenterologie: OMS 1044/2013

Etape medicale si

universitare

1995-2001 Universitatea de Medicina si Farmacie „Carol Davila” Bucuresti

In prezent

Pozitia ocupata: Sef de lucrari, Medic primar gastroenterologie

Tipul sau sectorul de activitate: Asistenta medicala de specialitate,

gastroenterologie

2016 - prezent Sef de lucrari UMF Carol Davila

2013 -prezent Medic primar gastroenterologie - OMS 1044/2013

2007 - prezent Medic specialist gastroenterologie - OMS 2140/2007. Centrul pentru Boli

Digestive si Transplant Hepatic, Institutul Clinic Fundeni, Bucuresti.

2007 - 2010 Cercetator prin concurs validat de Academia de Stiinte Medicale cu adeverinta nr

496/2007. Centrul pentru Boli Digestive si Transplant Hepatic, Institutul Clinic

Fundeni, Bucuresti

2002-2006 Medic rezident gastroenterologie - Certificat 073/ 12.12.2002. Centrul pentru

Boli Digestive si Transplant Hepatic, Institutul Clinic Fundeni, Bucuresti.

2003-2007 Asistent de cercetare, prin concurs validat de Academia de Stiinte Medicale cu

adeverinta nr 91/2003. Centrul pentru Boli Digestive si Transplant Hepatic,

Institutul Clinic Fundeni, Bucuresti



2002

Diploma de licenta Nr 545/21.03.2002, Titlul de Doctor - Medic, absolvent UMF

„Carol Davila Bucuresti”, Facultatea de Medicina.

2001-2002 Spitalul Universitar de Urgenta, Bucuresti : 1 stagiu clinic de Neonatologie si

Institutul Clinic Fundeni, Clinica de Pediatrie - 1 stagiu clinic de Pediatrie in

Cadrul Rezidentiatului de Pediatrie

2002-2007 Centrul de Gastroenterologie si Hepatologie Fundeni: medic rezident

gastroenterologie

2006-2010 Studii doctorale sub coordonarea Prof Dr. Irinel Popescu

2007-2010 Bursa de cercetare pentru Tinerii Doctoranzi acordata de Consiliul National de

Cercetare Stiintifica

2010 Doctor in Medicina. Ordin MECTS Nr 4387/06.06.2011. Titlul Tezei de Doctorat:

„Hepatita recurenta C posttransplant hepatic – strategii terapeutice si factori

asociati cu recurenta severa”

2011 Obtinerea Diplomei Europene in Medicina de Transplant – Modulele 1 (Trunchi

Comun) si 4 (Transplantul hepatic) prin examen sustinut la Glasgow pe 7

Septembrie 2011

Afiliere la societati si

publicatii profesionale

2001 - in prezent Membru al Societatii Romane de Gastroenterologie & Hepatologie (SRGH)

2001 – in prezent Membru al Societatii Romane de Endoscopie Digestiva

(SRED)

2002 – 2004 Membru al Socientatii Romane de Nutritie Enterala si Parenterala (ROSPEN)

2002 – 2004 Membru a ROMTRANSPLANT

2003 - 2008 Membru al Asociatiei Internationale a Chirurgilor si Gastroenterologilor (IASG)

2004 - 2008 Membru al American College of Gastroenterology (ACG)

2005 – in prezent Membru al European Association for the Study of the Liver (EASL)

2007- in prezent Membru al Clubului Roman de Boala Crohn si Colita Ulcerativa (RCCC)

2008 – in prezent Membru al Societatii Internationale de Transplant (TTS)

2008 – in prezent Membru al Societatii Europene de Transplant de Organe (ESOT)

2009 – in prezent Membru Fondator al “Women Leaders in Transplantation” (WLIT)

2010 - 2011 Membru al Societatii Europene de Crohn si Colita (European Crohn’s and

Colitis Organization) (ECCO)

COMPETENΤE

PERSONALE Diploma Europeana in Medicina de Transplant – Modulele 1 (Trunchi

Comun) si 4 (Transplantul hepatic) - supraspecializarea Transplant Hepatic



Limba(i) maternă(e)

Romana

Alte limbi străine cunoscute ΙNΤELEGERE VORBIRE SCRIERE

Ascultare Citire Participare la

conversaţie Discurs oral

Engleza C2 C2 C2 C2 C2

Franceza B2 B2 B2 B2 B2

Germana A2 A2 A2 A2 A2

Scrieţi denumirea certificatului. Scrieţi nivelul, dacă îl cunoaşteţi. Niveluri: A1/2: Utilizator elementar - B1/2: Utilizator independent - C1/2: Utilizator experimentat

Cadrul european comun de referinţă pentru limbi străine

Competenţe de comunicare Bune competenţe de comunicare dobândite prin experienţa in cadrul activitatii

clinice si de cercetare de peste 14 ani, participant cu lucrari de specialitate la

numeroase manifestari stiintifice internationale si nationale

Autor de lucrari publicate in reviste cu peer review si recenzori internationali

Functii administrative

si de conducere

2012 – prezent

2018 – prezent

2019 – 2023

Reprezentant National in Bordul European de Medicina de Transplant

Secretar al RoALD (Romanian Association for Liver Diseases)

Secretar Senior al Bordului European de Medicina de Transplant

2014 - prezent Responsabil cu gestionarea datelor din Registrul National de Transplant in cadrul

Institutului Clinic Fundeni Bucuresti – Centrul pentru Boli Digestive si Transplant

Hepatic conform Ordinului ministrului Sanatatii 983/26 August 2014

Competente dobandite la

locul de munca

Endoscopie digestiva diagnostica (abilitate inclusa in standardul profesional).

Ultrasonografie generala (abilitate inclusa in standardul profesional).

Competente informatice Utilizator experimentat PC (MS Office, Windows).

Pregătire

postuniversitară

(CURSURI ŞI

SPECIALIZĂRI)

1 Noiembrie 2000 Curs Precongres: Simpozionul National de Gastroenterologie, Hepatologie si

Endoscopie Digestiva, Bucuresti, 2000

Aprilie 2001 EASL Post-Graduate Course: Clinical Management of Portal Hypertension and Its

Complications, 36-th EASL Meeting, Prague, CZECH REPUBLIC



Martie 2002 POSTGRADUATE COURSE IN HEPATO-GASTROENTEROLOGY organized

by The National French Society of Gastroenterology, Nantes, FRANCE

Aprilie 2002 Stagiu practic 2 saptamani in Clinica de Gastroenterologie a Spitalului “EDOUARD

HERRIOT”, LYON, FRANCE

6-7 Decembrie 2002 Simpozionul “Afectiuni peptice digestive la inceputul mileniului III – optiuni

diagnostic, solutii terapeutice”, Campina, Romania

18 Februarie 2003 Simpozionul “Noua generatie de terapie antivirala in hepatita cronica C”, Hotel

Crowne Plaza, Bucuresti

17-18 Martie 2003 Tehnica de montare endoscopica a gastrostomei percutane, Institutul Clinic Fundeni,

Bucuresti

9-11 Aprilie 2003 Al cincilea simpozion si curs postuniversitar al IASG “Actualitati in bolile ficatului”,

Bucuresti, Romania

24 Septembrie 2003 PRECONGRESS COURSE “Actualities in gastroenterology and hepatology”, 9-th

Congress of Gastroenterology, Hepatology and Gastrointestinal Endoscopy, Craiova,

Romania

3 Octombrie 2003 SIMPOZIONUL “ROLUL LIMFOCITELOR T IN IMUNOPATOGENEZA

HEPATITELOR CRONICE”, INSTITUTUL CLINIC FUNDENI, BUCURESTI

Octombrie 2003 ADVANCED POSTGRADUATE COURSE IN GASTROENTEROLOGY

organized by The Holland Digestive Disease Week Foundation, The Netherlands

19-23 Octombrie

2003

10 th CLINICAL COURSE OF EUROPEAN SOCIETY FOR CLINICAL

NUTRITION AND METABOLISM, Izvorani, Romania

Decembrie 2003 EASL School of Hepatology Course 1 – Chronic Liver Diseases

Geneva, Switzerland

12 Martie 2004 European Postgraduate Gastro-surgical School, 4th Amsterdam International Update

on Hepatology: Hepatitis B and C and Hepatocellular Carcinoma, Academic Medical

Center, Amsterdam, The Netherlands

3-4 aprilie 2004 POSTGRADUATE COURSE IN HEPATO-GASTROENTEROLOGY organized

by The National French Society of Gastroenterology, Paris, FRANCE

Iunie 2004 EASL School of Hepatology Course 2 – Complications of cirrhosis and liver cancer,

Barcelona, SPAIN

Septembrie 2004 PRECONGRESS COURSE: “ACTUALITATI IN GASTROENTEROLOGIE,

HEPATOLOGIE SI ENDOSCOPIE DIGESTIVA”. The XXVth National Symposium

of Gastroenterology, Hepatology and Gastrointestinal Endoscopy, Constanta,

Romania

13 Octombrie 2004 SIMPOZIONUL “STEATOZA HEPATICA NONALCOOLICA”, SIBIU,

ROMANIA

25 Septembrie 2004 EASL Post-Graduate Course: Liver Transplantation – State of the Art and Novel

Developments, 12th UEGW, Prague, CZECH REPUBLIC

11-12 Noiembrie 2004 Curs de Nutritie Clinica si Metabolism, Poiana Brasov, Romania

13-14 Aprilie 2005 EASL Post-Graduate Course: The Liver Clinic in the Post-Genomic Era, 40 th EASL

Meeting, Paris, France

1 Iunie – 30

Noiembrie 2005

DAAD Scholarship – LIVER TRANSPLANTATION SPECIALISATION,

University Hospital Essen, Germany

12-16 Decembrie

2005

Simpozionul “Clasic si modern in patologia digestiva”, Institutul Clinic Fundeni,

Bucuresti

12-14 Ianuarie 2006 Monothematic Conference: Liver Transplantation for Viral Hepatitis, Paris, Franta

3 Martie 2006 Workshop cu participare internationala cu tema: “Impactul clinic al ecoendoscopiei

diagnostice si terapeutice”, Institutul Clinic Fundeni, Bucuresti



26-30 Aprilie 2006 EASL Postgraduate Course: “Immunological phenomena in hepatitis C in and

outside of the liver”, the 41st Annual Meeting of the European Association for the

Study of the Liver, Vienna, Austria

20-21 Mai 2006 AGA Postgraduate Course: “Recognizing and reducing risk in GI practice”, Digestive

Disease Week, Los Angeles, United States

21 Mai 2006 SSAT (The Society for Surgery of the Alimentary Tract) Postgraduate Course, Los

Angeles, CA, USA.

14 Iunie 2006 Cursul Pre-Simpozion “Curs de Gastroenterologie, Hepatologie si Endoscopie

Digestiva”, Al XXVII-lea Simpozion National de Gastroenterologie, Hepatologie si

Endoscopie Digetiva”, Poiana Brasov – Hotel Piatra Mare

2006 Simpozionul “Sindromul Barrett – de la boala de reflux gastroesofagian la

adenocarcinomul esofagian”, Institutul Clinic Fundeni, Bucuresti

Octombrie 2006 VERUM.EDU seminar on “Basics on Good Clinical Practice for investigators”

Octombrie 2006 ESGE Postgraduate Course: “Endoscopic Oncology; Practice of Endoscopy”, 14th

United European Digestive Week, Berlin, Germany

Octombrie 2006 EASL Postgraduate Course: “Current and Future Therapeutic Options for Viral

Hepatitis”, 14th United European Digestive Week, Berlin, Germany

1 Februarie – 31

Decembrie 2006

Curs deschis la distanta, Universitatea de Medicina si Farmacie “Iuliu Hatieganu”

Cluj-Napoca

11 Aprilie 2007 EASL Postgraduate Course: “The microscope at the bedside”, the 42nd Annual

Meeting of the European Association for the Study of the Liver, Barcelona, Spain

11-12 Iunie 2007 Third International Symposium on Living Donor Organ Transplantation, Essen,

Germany

27-28 Octombrie

2007

Postgraduate Course: “Recent Advances in Imaging for

Gastrointestinal and Liver Diseases”, 15th United European Digestive Week, Paris,

France

Octombrie 2007 EASL Postgraduate Course:”Portal hypertension”, 15th United European Digestive

Week, Paris, France

23-24 Aprilie 2008 EASL Postgraduate Course: “Complications of portal hypertension”, the 43rd Annual

Meeting of the European Association for the Study of the Liver, Milan, Italy

17-18 Mai 2008 Spring Postgraduate Course: Gastroenterology and Hepatology 2008: Challenges and

Controversies, San Diego CA, USA.

31 Mai- 3 Iunie 2008 The Postgraduate course: “Ultrasound in Gastroenterology and Hepatology”,

EUROSON 2008, Timisoara, Romania

5 Decembrie 2008 Simpozionul “Provocarile terapiei optime in hepatita cronica B”, Institutul National

de Boli INfectioase “Prof Dr Matei Bals”, Bucuresti

17 Iunie 2009 9th ECCO Educational Workshop, Cluj-Napoca, Romania

18 Iunie 2009 Curs precongres. Al XXIX-lea Simpozion National de Gastroenterologie, Endoscopie

Digestiva si Hepatologie, Cluj Napoca

Ianuarie 2009-

Decembrie 2009

Doctoral research fellowship in liver transplantation, University Hospital Essen,

Germany

21-22 Noiembrie

2009

17th UEGW Postgraduate Teaching Programme, Londra, Marea Britanie

14-15 Aprilie 2010 Postgraduate Course:MANAGEMENT OF ACUTE CRITICAL CONDITIONS IN

HEPATOLOGY, 45 Annual Meeting of EASL, Viena, Austria

4 Iunie 2010 Simpozionul National „IBISCUS Bucharest Contrast Enhanced Ultrasound –

Routine Tool in General Imaging”, Bucuresti



9-10 Iunie 2010 Curs Precongres: Al XXX-lea Simpozion National de Gastroenterologie, Endoscopie

Digestiva si Hepatologie, Craiova

24-25 Septembrie

2010

Al II-lea Simpozion National de Boli Inflamatorii Cronice Intestinale cu participare

internationala, Mamaia, Romania

27-30 Septembrie

2010

IASGO CME Postgraduate Course “Liver Transplantation – An interdisciplinary

Approach”, Essen, Germany

22-23 Octombrie

2011

Postgraduate Teaching Programme, 19th UEGW Stockholm, Sweden

4 Noiembrie 2011 AASLD/ILTS Transplant Course: Liver Transplant Immunosuppression: “Does One

Size Fit All?”; 62nd AASLD Meeting, San Francisco, USA

18-19 Aprilie 2012 EASL Postgraduate Course: Parasitic, “Imported” and Alcoholic Liver Disease,

Barcelona, Spain

14 Iunie 2012 EAGEN Postgraduate Course: “Complication of Inflammation and Infection in the

Gastrointestinal Tract”, Targu Mures, Romania

14-15 Iulie 2012 Postgraduate Weekend, 24th International Congress of the Transplantation Society,

Berlin, Germania

20 Septembrie 2012 27th ECCO Educational Workshop: „ECCO Guidelines”, Sibiu 20 Septembrie 2012

9-10 Aprilie 2013 Clinical Observation Program – Liver Unit, Vall d’Hebron University Hospital

Barcelona, Spain

9-10 Aprilie 2014 EASL-IASL Postgraduate course: “Acute Liver failure/Acute on Chronic liver

failure: perspective of the East and West”, London, United Kingdom

25-26 Aprilie 2014 Up-To-Date in Hepatology, Annual Course – “Viral Hepatitis and Liver Cirrhosis” –

Current Challenges and Future Directions, Bucharest, Romania

26-28 Iunie 2014 “Scoala de vara Medicina Interna-Gastroenterologie”, Paltinis, Romania

6 Martie 2015 ESOT Course: Liver transplantation in HCV positive recipients: facing a new Era

22-23 Aprilie 2015 EASL Postgraduate course – “Metabolic liver disease”, Viena Austria

22 Aprilie 2015 EASL-ILTS-ELITA-LICAGE Post Graduate Course – “Liver Transplant”, Viena,

Austria

27-28 Mai 2015 Up-To-Date in Hepatology, Annual Course – “Portal hypertension and its

complications after Baveno VI Consensus Conference”; “Viral Hepatitis Anno 2015:

Curring the Disease”, Bucharest, Romania

29-30 Mai 2015 EASL Monothematic Conference: “Liver Diseases in resource-limited Settings”

Bucharest, Romania

9 Iunie 2015 Cursul de Gastroenterologie si Hepatologie, Iasi 10-13 iunie 2015

26-28 Iunie 2015 15th International Symposium on Viral Hepatitis and Liver Disease (ISVHLD),

Berlin, Germany

8 Iulie 2015 Current controversies in liver transplantation – Satellite symposium to the ILTS 21st

Annual International Congress, Chicago USA

10 Iulie 2015 Managing HCV in Liver Transplant: Optimizing Success with New DAA Regimens,

Chicago, USA

17-19 Martie 2016 Al 11 lea Simpozion Nicolae Cajal – Mecanisme Moleculare ale Bolilor Acute

si Cronice, Bucuresti, Romania

28-29 Aprilie 2016 3rd UpDate on Hepatology, Course Bucharest 2016, Romania, 28-29 Aprilie

2016, Bucuresti, Romania – „Clinical Challenges, Unmet Needs and Emerging

Therapies in Hepatology”

28-29 Octombrie

2016

Hepatology Academy Preceptorship Program, Universitats Klinikum Frankfurt



11 Noiembrie 2016 AASLD/ILTS Transplant Course “The Next 10 Years: Innovations

Transforming Outcomes in Liver Transplantation” Boston, Massachussets

12-13 Decembrie

2016

Hepatology Academy Preceptorship Center of Excellence Curriculum,

University of Milan, Milan, Italy

29 January 2017 International Hepatitis C Exchange, Paris, France

30-31 January 2017 10th Paris Hepatology Conference – International Conference on the

Management of Liver Diseases

2-5 February 2017 EASL HCC Summit 2017, Geneva, Elvetia

3 Martie 2017 Conferinta „Tratamente inovative in Oncologie – Editia a IIIa – Analiza

moleculara si terapia individualizata in cancer”, Bucuresti, Romania

6-7 Aprilie 2017 4th UpDate on Hepatology, Course Bucharest 2016, Hepatology 2017 – A

panoramic view, Romania, 6-7 Aprilie 2017, Bucuresti, Romania

19 April 2017 PGC on Liver Transplantation: Current challenges in liver transplantation, The

International Liver Congress (ILC) 2017, Amsterdam, Olanda

19 April 2017 PGC on Liver Transplantation: Liver transplantation for viral hepatitis, ILC

2017, Amsterdam, Olanda

19 April 2017 BSS – Hepatic regenerative medicine: Artificial and natural 3D scaffolds for

liver tissue bioengineering, ILC 2017, Amsterdam, Olanda

20 April 2017 PGC – A multidisciplinary approach to patients with liver disease:

Hepatocellular carcinoma, ILC 2017, Amsterdam, Olanda

20 April 2017 PGC – A multidisciplinary approach to patients with liver disease: Non-

alcoholic fatty liver disease, ILC 2017, Amsterdam, Olanda

12-13 May 2017 Hepatology Academy, Standalone Meeting, Paris, Franta

22-24 Iunie 2017 Al 37lea Congres National de Gastroenterologie, Hepatologie si Endoscopie

Digestiva, Bucuresti, Romania

8-9 Septembrie 2017 Pancreatic Fest 2017, Bucharest, Romania

15-16 September

2017

Hope for Cure Vernissage, Budapesta, Hungary

24-27 Septembrie

2017

18th Congress of the European Society for Organ Transplantation, Barcelona,

Spania

28-30 September

2017

9th National Symposium on Inflammatory Bowel Disease, Bucharest, Romania

6-8 October 2017 Congresul National de Radiologie si Imagistica Medicala, Bucuresti, Romania

16-17 October 2017 King’s College Hospital London – Hepatology Academy Perceptorship

10-11 November 2017 Liver Elastography Course, Timisoara, Romania

29 March 2018 Al X-lea Congres al Asociatiei Romtransplant, Bucuresti, Romania

11-15 April 2018 The International Liver Congress, Paris, France

26-27 April 2018 5th UpDate on Hepatology Course – Best Practices in Clinical Hepatology,

Bucharest, Romania

24-26 May 2018 Al 38-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie

Digestiva, Craiova, Romania

2-5 June 2018 Digestive Disease Week 2018: Monumental Developments in Science and

Medicine, Washington, USA

17 Septembrie 2018 Simpozion Stiintific Aniversar – 60 ani de SRGH

19-21 Septembrie

2018

National Congress of the Romanian Association

of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation – 12th edition,

Cluj Napoca, Romania

3-6 Octombrie 2018 Zilele Institutului Clinic Fundeni 2018



1-4 aprilie 2019 TTT (Train the Trainers) Workshop organized by World Gastroenterology

Organisation (WGO), Bucuresti, Romania

5-6 Aprilie 2019 6th UpDate on Hepatology Course “From theory to Practice in Liver Diseases,

Bucuresti, Romania

11-14 Aprilie 2019 The International Liver Congress (ILC) 2019, Vienna, Austria

10-11 Aprilie 2019 Postgraduate Course “End stage Liver Disease”, ILC 2019, Vienna, Austria

19-20 Aprilie 2019 Corelatii anatomopatologice si clinice in gastroenterology, Curs-editia I,

Athenee Palace Hilton - Bucuresti

6-8 Iunie 2019 Al 39 lea Congresul National de Gastroenterologie, Hepatologie si Oncologie

Digestiva, Timisoara, Romania

8-10 Iulie 2019 Zilele Institutului Clinic Fundeni 2019

15-18 Septembrie

2019

19th Congress of the European Society for Organ Transplantation, Copenhaga,

Danemarca

19-21 Septembrie

2019

Digestive Endoscopy Cluj 2019

7th Transylvanian Meeting for Liver Interventions

Premii, burse,

recunoasterea

meritului

stiintific

Premii Internationale (22)

18-22 Aprilie 2001 Travel Bursary Award, 36th Annual Meeting of European Association for the Study of the

Liver (EASL), Prague, Czech Republic

28 Septembrie – 3

Octombrie 2001

Travel Bursary Award, Falk Symposia No. 124-126, “Progress in Gastroenterology and

Hepatology” Hannover, Germany

1-4 Noiembrie

2001

Certificate of appreciation in recognition of scientific excellence in the free paper (poster)

category: Liver and Biliary Diseases

11th World Congress of the International Association of Surgeons and Gatroenterologists

(IASG), Heraklion, Crete-Greece

23-27 Martie 2002 Bursary Award, The French Days of Digestive Pathology, Nantes, France

18-21 Aprilie 2002 Travel Bursary Award – Best Eastern European Abstract, 37th Annual Meeting of European

Association for the Study of the Liver (EASL), Madrid, Spain

12-17 Octombrie

2004

Travel Bursary Award, Falk Symposia No. 142-144, “Gastroenterology Week Freiburg

2004” Freiburg, Germany

13-17 Aprilie 2005 Young Investigator Full Bursary Award, 40th Annual Meeting of European Association for

the Study of the Liver (EASL), Paris, France

26-30 Aprilie 2006 Young Investigator Full Bursary Award, 41st Annual Meeting of European Association for

the Study of the Liver (EASL), Vienna, Austria

23-24 Martie 2007 Travel Bursary Award, Falk Symposium No. 158, “Intestinal Inflammation and Colorectal

Cancer” Seville, Spain

23-27 Aprilie 2008 Young Investigator Full Bursary Award, 43rd Annual Meeting of European Association for

the Study of the Liver (EASL), Milan, Italy



28 Iunie -1 Iulie

2008

Invited at TTS New KOL Meeting as New Key Opinion Leader (nKOL), Sankt Petersburg,

Russia – “Real time elastography – a noninvasive tool for evaluation of recurrent hepatitis C

following liver transplantation.”

10-14 August 2008 Travel Scholarship,The XXII International Congress of The Transplantation Society, Sydney,

Australia

17 Septembrie

2008

First prize: Falk Workshop “Strategies of Cancer Prevention in Gastroenterology”, Mainz,

Germany for the paper “Early Diagnosis of small hepatocellular carcinoma in cirrhotic

patients using real-time elastography”

17 Septembrie

2008

Travel Bursary Award, Falk Workshop “Strategies of Cancer Prevention in

Gastroenterology”, Mainz, Germany

18-19 Septembrie

2008

Travel Bursary Award, Falk Symposium no 166, “GI Endoscopy – Standards and

Innovations”, Mainz, Germany

20-21 Septembrie

2008

Travel Bursary Award, Falk Symposium no 167, “Liver under constant attack – from fat to

viruses”, Mainz, Germany

17-18 Octombrie

2009

Travel Bursary Award, Falk Symposium no 171, “Liver and metabolic syndrome”,

Hannover, Germany

14-18 April 2010 Young Investigator Full Bursary Award, 45th Annual Meeting of European Association for

the Study of the Liver (EASL), Vienna, Austria

15-19 August 2010 Emerging Economy Travel Award, The XXIII International Congress of The

Transplantation Society, Vancouver, Canada : P37.57 – Survival outcomes following liver

transplantation (SOFT) score - A useful predictor of short term mortality in Romanian

Liver Transplant Program

30 March-3 April

2011

Young Investigator Full Bursary Award, The International Liver Congress 2011 - 46th

Annual Meeting of European Association for the Study of the Liver (EASL), Berlin,

Germany

4-7 Septembrie

2011

Travel Grant City of Glasgow – 15th Congress of the European Society for Organ

Transplantation 22nd Annual BSHI Conference, Glasgow, United Kingdom

18-22 Aprilie 2012 Registration Bursary - International Liver CongressTM 2012 by EASL, Barcelona, Spain

Premii Nationale (24)

13-16 Iunie 2002 Mentiune pentru lucrarea “Importanta investigatiilor biochimice la pacientii cirotici cu

infectie spontana a lichidului de ascita care suprapun sindrom hepatorenal” prezentata in

cadrul Simpozionului National de Gastroenterologie, Cluj 2002

24-27 Septembrie

2003

Premiul pentru cea mai buna lucrare prezentata in cadrul celui de-al XXIV-lea Simpozion

National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Craiova 2003:

“Epidemiology of inflammatory bowel disease in adult population in Romania”

24-27 Septembrie

2003

Premiul Poster pentru lucrarea prezentata la cel de XXIV-lea Simpozion National de

Gastroenterologie, Hepatologie si Endoscopie Digestiva, Craiova 2003:“Death predicting

factors on the waiting list for liver transplantation”

1-3 Septembrie

2004

Premiul II – Postere la cel de-al XXV-lea Simpozion National de Gastroenterologie,

Hepatologie si Endoscopie Digestiva, Constanta 2004, pentru lucrarea: “Efficacy of

prophylactic banding ligation of high risk esophageal varices in cirrhotic patients on the

waiting list for liver transplantation”

11-14 Noiembrie

2004

Mentiune pentru Concursul pe teme de Nutritie Clinica organizat de Fresenius Kabi

Romania

15-17 Iunie 2006 Prize for the best oral presentation – section “Viral hepatitis, new techniques, varia”, The

XXVIIth National Symposium of Gastroenterology, Hepatology and Gastrointestinal

Endoscopy, Poiana Brasov, Romania



18-19 Aprilie 2008 Mentiune pentru prezentare sub forma de Poster la Congresul Anual al Asociatiei

Medicale Române, 18-19 Apilie 2008; Academia Romana, Bucuresti –“ Evaluarea

elastografică în timp real a pacienţilor cu hepatită C recurentă posttransplant hepatic”

18-20 Iunie 2008 Premiul II al SRGH pentru lucrarea prezentata la al XXIX-lea Simpozion National de

Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj-Napoca 2009: “ ASCA and

ANCA serology in Romanian IBD Patients”.

18-20 Iunie 2008 Premiul II al SRGH pentru posterul prezentat la al XXIX-lea Simpozion National de

Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj-Napoca 2009: “The prevalence

of anti-hepatitis B core antibodies in Romania.”

18-20 Iunie 2008 Premiul II al SRGH pentru lucrarea prezentata oral la al XXIX-lea Simpozion National

de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Cluj-Napoca 2009: “ Prediction

of death on large waiting lists for liver transplantation using MELD exceptions.”

27-28 November

2008

Premiul I – Postere. Sesiunea Stiintifica a Institutului Clinic Fundeni si a Institutului de Boli

Cardiovasculare Prof. Dr. C. C. Iliescu: Investigarea profilului de expresie a genelor

implicate in medierea reactiilor inflamatorii la pacientii cu IBD utilizand tehnica MLPA

27-28 Noiembrie

2008 Premiul III pentru prezentarea orala – “Elastografia in timp real – nou marker pentru

evaluarea fibrozei hepatice la pacientii cu hepatita cronica C recurenta post transplant

hepatic”, Scientific Meeting of Fundeni Clinical Institute, 27-28 November 2008,

Bucharest

18 – 20 Iunie 2009 Premiul III pentru prezentarea orala – “Factori de risc ai recurentei carcinomului

hepatocelular dupa tratamentul chirurgical”, The XXIXth National Symposium of

Gastroenterology, Hepatology and Gastrointestinal Endoscopy, Cluj-Napoca, Romania

19-21 Mai 2011 Premiul III al SRGH pentru lucrarea: “Poate fi utilizat polimorfismul genei IL28B pentru

predictia raspunsului virusologic precoce la pacienti cu hepatita recurenta post transplant

Hepatic?”.al XXXI-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie

Digestiva

26 Aprilie 2012

Premiul “Eugen Proca”/2011 pentru Stiinte Medicale pentru cartea “Transplantul

hepatic”, Editura Medicala, Bucuresti, 2011, Academia Oamenilor de Stiinta din Romania

20 Ianuarie 2013 Gala Premiile MEDICA ACADEMICA, Editia a 4a, Premiul oferit de Fundatia “Nicolae

Cajal” pentru cea mai buna realizare in domeniul cercetarii fundamentale in medicina,

Bucuresti

12-15 Iunie 2013 Premiul I al Societatii Romane de Gastroenterologie pentru lucrarea prezentata in cadrul

celui de-al XXXIII-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie

Digestiva, Timisoara 2013: Expresia genica cantitativa a factorilor de transcriptie hepatici

poate fi utilizata pentru predictia recurentei tumorale la pacientii cu hepatocarcinom tratati cu

viza curativa

12-14 Iunie 2014 Premiul SRGH pentru cea mai buna prezentare orala: „Profilul de expresie genica al

genelor specifice celulelor stem/progenitoare hepatice in hepatocarcinom si semnificatiile

prognostice”, Al XXXIV-lea Congres National de Gastroenterologie, Hepatologie si

Endoscopie Digestiva, Oradea

13 Iunie 2014 Diploma de Tanar Cercetator pentru merite deosebite in activitatea de cercetare din partea

Societatii Romane de Gastroenterologie si Hepatologie, Al XXXIV-lea Congres National de

Gastroenterologie, Hepatologie si Endoscopie Digestiva, Oradea

1-4 Aprilie 2015 Premiul „Herbert Beller Barbu” pentru tineri cercetatori pentru lucrarea prezentata in

cadrul celui de-al X-lea Simpozion „Acad. Nicolae Cajal”: “Deletia rs199508964 din exonul

6 al genei IRF5 se coreleaza cu polimorfismul genei Il28B rs12980275 si prezice raspunsul

virusologic sustinut la pacientii cu hepatita recurenta C post-transplant hepatic”.



ACTIVITATEA DE

CERCETARE

STIINTIFICA:

PROIECTE DE

CERCETARE-

DEZVOLTARE-

INOVARE

OBTINUTE PRIN

COMPETITIE PE

BAZA DE

CONTRACT/GRANT

TITLU (ACRONIM) Perioa

da Functie

Grant/Proiect National

1.

Proiect VIASAN 324/2004. Rolul evidentei

computerizate a pacientilor in identificarea

potentialilor candidati pentru transplantul hepatic

si in urmarirea dinamicii listei de asteptare

(HEPASIST). Buget: 920000000 ROL

2004-

2006 Cercetator

2.

Proiect VIASAN 322/2004. Rolul manometriei

esofagiene in diagnosticul achalasiei la pacientii

cu disfagie si in evaluarea eficientei tratamentului

endoscopic sau chirurgical al afectiunii

(ROMAC). Buget: 1265000000 ROL

2004-

2006 Cercetator

3.

Proiect VIASAN 428/2004. Evidenta

computerizata prospectiva a pacientilor cu risc

pentru dezvoltarea cancerului colorectal la care se

impune screeningul si supravegherea

(COLOCANS). Buget: 920000000 ROL

2004-

2006 Cercetator

4. Proiect CEEX 142/2006. Diagnosticul non-invaziv 2006- Cercetator

17 Aprilie 2015 Diploma de Excelenta – cu ocazia aniversarii in Romania a 15 ani de transplant hepatic si

600 de operatii efectuate cu success (2000-2015)

30 Septembrie

2015

Diploma de Excelenta si Recunostinta pt profesionalism si daruire in ingrijirea pacientilor

Institutului Clinic Fundeni - Zilele Institutului Clinic Fundeni 2015

29 Aprilie 2016 Premiul I pentru Posterul prezentat in cadrul cursului 3rd UpDate on Hepatology, Course

Bucharest 2016, Romania, 28-29 Aprilie 2016, Bucuresti, Romania – „Clinical Challenges,

Unmet Needs and Emerging Therapies in Hepatology” cu titlul: „Hepatocyte telomerase

expression in hepatocellular carcinoma and chronic liver disease”

2018 Premiul II pentru Prezentarea Orala „Factori predicivi pentru regresia cirozei hepatice la

un an dupa eradicarea VHC”. In cadrul Mesei Rotunde “Lucrari originale”. Al 38-lea

Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, 24-26 Mai

2018, Craiova, Romania

2019 Premiul I pentru Posterul cu titlul „Metabolic syndrome in liver transplant recipients – The

role of genetic testing and blood based biomarkers” prezentat in cadrul cursului „6th Update

on Hepatology Course”, 5-6 Aprilie 2019, Bucuresti

2019 Winner of the Academic Debate cu titlul ”Controversy 1. Liver transplant beyond Milan

criteria. Pro.” din cadrul celui de al 39-lea Congres National de Gastroenterologie,

Hepatologie si Oncologie Digestiva, 6-8 iunie 2019, Timisoara, Romania



si markeri de prognostic ai hepatocarcinomului

detectat in leziunile focale nodulare din ciroza

hepatica (PROSONOHEP). Buget: 1500000 RON

2008

5.

Proiect CEEX 89/2006. Implicaţii diagnostice şi

prognostice ale aspectului endomicroscopic al

microvascularizaţiei leziunilor premaligne şi

maligne ale tubului digestiv superior

(DIAPROGENDO). Buget: 1500000 RON

2006-

2008 Cercetator

6.

Proiect CEEX 60/2006. Evaluarea fenotipica si

genotipica a pacientilor cu boli inflamatorii

intestinale cronice din Romania si generarea unui

registru biregional computerizat de urmarire

prospectiva (IBDPROSPECT). Buget: 1500000

RON

2006-

2008 Cercetator

7.

Proiect CEEX 65/2006. Potenţialul Terapeutic al

Celulelor Stem Hematopoietice în Afecţiunile

Hepatice (LIVERSTEM). Buget 1500000 RON

2006-

2008 Cercetator

8.

Proiect PNII 42170/2008 ENDONERD Valoarea

endomicroscopiei confocale laser si a endoscopiei

cu magnificatie, in banda ingusta (NBI), in

diagnosticul bolii de reflux gastroesofagian

nonerozive. Buget: 1521600 RON

2008-

2011 Cercetator

9.

Proiect PNII 42169/2008 GENOWIL Valoarea

diagnostica si prognostica a analizei genetice si

corelatii genotip-fenotip la pacientii cu boala

Wilson. Buget: 1963000 RON

2008-

2011 Cercetator

10.

Proiect 42162/2008 BAROFAT (Valoare totala)

Factori predictivi ai raspunsului serologic,

imagistic, imunohistochimic si histologic hepatic

la pacientii cu obezitate morbida si ficat gras

nonalcoolic supusi chirurgiei bariatrice. Buget:

1850000 RON

2008-

2011 Cercetator

11.

Proiect PNII- PCE 125/2011. Molecular predictors

of prognosis following curative treatment of

hepatocellular carcinoma – the significance of

liver stem/progenitor cells genes, Buget: 1437500

RON

2011-

2016 Cercetator

12.

Proiect finantat prin programul „Cercetare in domenii

prioritare”, mecanismul financiar al Spatiului

Economic European (SEE). EEA-JRP Romania-

Norvegia Nr proiect 4SEE. Stratificarea pacientilor cu

carcinom hepatocelular prin identificarea unor

markeri neinvazivi. Buget: 1125000Eur, Co-finantare

privata: 180916 EUR

2014-

2017 Cercetator

13

Proiect POCU/91/4/8/107931, finantat din fonduri

europene nerambursabile, implementat de catre

Institutul Clinic Fundeni din Bucuresti avand titlul

2018-

2020

Responsabil

curicula

VHC



“Program de formare a personalului medical din

România în managementul pacienților infectați cronic

cu virusuri hepatitice B și C - HEPATER”

14

Proiect PN-III-P1-1.1-TE-2016-1109 “Effect of

immunosuppression agents on human hepatocyte and

non-parenchymal liver cells apoptosis”(APOHEPI)

2018-

2020

Director

proiect

15 Proiect de mobilitate pentru cercetatori PN-III-P1-1.1-

MC-2018-1674 2018

Director

proiect

Studii multicentrice internationale

1

SR121463B in cirrhotic ascites treatment with

normonatremia: a placebo-controlled dose-

comparison study (NORMO-CAT)

2004 Co-

investigator

2


hyponatremia: a placebo-controlled dose-comparison

study (HYPO-CAT) (No LTS5634)

2004 Co-

investigator

3


hyponatremia: a single-blind, placebo-controlled,

long-term treatment study (EXPO-CAT) (No

LTS5634)

2004-

2006

Co-

investigator

4

Satavaptan in the prevention of ascites recurrence: a

double-blind, randomized, parallel-group comparison

of satavaptan at 5 to 10 mg daily vs placebo in the

absence of diuretics in patients with recurrent ascites

due to cirrhosis of the liver (SPARe-2) (EFC 6682)

(Phase III)

2006-

2008

Co-

investigator

5

Satavaptan cirrhotic ascites treatment study:a double-

blind, randomized, parallel-group comparison of

treatment with satavaptan at 5 to 10mg daily versus

placebo on top of conventional treatment in patients

with ascites due to cirrhosis of the liver (EFC 4492)

(Phase III)

2006-

2008

Co-

investigator

6

Randomized, Multicenter, double-blinded, phase IV

study evaluating the efficacy (as measured by

sustained virological response) and safety of 360µg

induction dosing of Pegasys in combination with

higher Copegus doses in treatment naïve patients with

chronic hepatitis C genotype 1 virus infection of high

viral titer and baseline body weight greater than or

equal to 85kg (Protocol no NV18210A)

2006-

2008

Co-

investigator

7

A phase 3b, Randomized, Double-Blind, Double-

Dummy Study Evaluating the Antiviral Efficacy,

Safety and Tolerability of Tenofovir Disoproxil

Fumarate (DF) Monotherapy versus Emtricitabine

2008-

2013

Co-

investigator



plus Tenofovir DF Fixed-Dose Combination Therapy

in Subjects with Chronic Hepatitis B who are resistant

to Lamivudine – GS-US-174-0121

8

A phase III, randomized, double-blind trial to evaluate

the efficacy, safety and tolerability of TMC435 vs

telaprevir, both in combination with PegIFN alpha 2a

and ribavirin in chronic hepatitis C genotype 1

infected subjects who were null or partial responders

to prior PegIFN alpha and ribavirin therapy (ATTAIN

Study, TMC435HPC3001)

2012-

2014

Co-

investigator

9

A randomized, open-labeled study to evaluate the

efficacy and safety of ABT-450/Ritonavir/ABT-267

and ABT-333 co-adminstred with ribavirin compared

to telaprevir co-administred with pegylated interferon

α-2a and ribavirin in treatment-experienced adults

with chronic hepatitis C genotype-1 virus infection

(MALACHITE-II)

2013-

2015

Co-

investigator

10

An International, Multi-Center Study evaluating the

correlation of IL28B genotypes with chronic hepatitis

C disease characteristics and patient demographics

(MV25600)

2011-

2013

Co-

investigator

11

Non-Interventional Cohort Study on the Utilization

and Impact of Dual and Triple Therapies Based on the

Pegylated Interferon for the Treatment of Chronic

Hepatitis C (MV25599)

2012-

2014

Co-

investigator

12

A Phase III, Open-Label Clinical Trial to study the

efficacy and safety of the combination regimen of

MK-5172/MK-8742 versus Sofosbuvir/Pegylated

Interferon/Ribavirin (PR) in treatment-naive and PR

prior treatment failure subjects with chronic HCV

GT1, 4 or 6 infection (MK 5172-077)

2014-

2017

Co-

investigator

13

An Open-Label, Multicenter Study to evaluate long-

term outcomes with ABT-450/Ritonavir/ABT-267

(ABT-450/r/ABT-267) and ABT-333 with or without

ribavirin (RBV) in adults with genotype 1 chronic

hepatitis C virus (HCV) infection (TOPAZ-I) (M14-

423)

2014-

2017

Co-

investigator

14

A Study of Glecaprevir (GLE)/Pibrentasvir (PIB) in

Treatment-Naive Adults With Chronic Hepatitis C

Virus (HCV) Genotype 1-6 Infection and

Compensated Cirrhosis (M16-135)

2017-

2018

Co-

investigator

15

A 52-week, placebo-controlled, randomized, Phase 3

study to evaluate the safety and efficacy of seladelpar

in subjects with primary biliary cholangitis (PBC) and

an inadequate response to or an intolerance to

ursodeoxycholic acid (UDCA) (CB8025-31735)

2019-

2021

Co-

investigator



16

A Multicenter, Randomized, Double-Blind,

Placebo-Controlled Phase III Study to Evaluate the

Efficacy and Safety of Elafibranor in Patients with

Nonalcoholic Steatohepatitis (NASH) and fibrosis

(GFT505-315-1)

2017-

2020

Co-

investigator

Studii multicentrice nationale

1

Observational, retrospective cohort study to evaluate

pretreatment and on treatment predictors of response

to peginterferon alfa and ribavirin therapy in chronic

viral Hepatitis C in real life medical practice in

Romania (HERO 1) – protocol ML 21909

2008-

2009

Co-

investigator

2

Proiectul integrat de testare-diagnostic-tratament

pentru subiectii cu risc crescut de hepatita C care se

adreseaza unitatilor medicale tertiare din Romania :

HepC Awareness-Linkage to care-

Epidemiological-Research-Treatment (HepC

A.L.E.R.T.)

2019

Fundeni

Clinical

Institute

Coordinator

PUBLICATII

Indice Hirsch Core Collection: 14 Citari: 738 Citari fara self citari: 716 Indice Hirsch All databases: 17 Citari: 1011 Citari fara self citari: 974

Lista Completa de Lucrari:

I. Lista lucrarilor semnificative:

1. Speranta Iacob, Vito R. Cicinnati, Philip Hilgard, Razvan A. Iacob, Liana S. Gheorghe, Irinel

Popescu, Andrea Frilling, Massimo Malago, Guido Gerken, Christoph E. Broelsch, Susanne

Beckebaum. Predictors of graft and patient survival in HCV recipients - model to predict HCV

cirrhosis following liver transplantation. Transplantation 2007; 84:56-63

2. Cicinnati VR, Iacob S, Klein CG, Baba HA, Sotiropoulos GC, Hilgard P, Erim Y, Broelsch CE,

Gerken G, Beckebaum S. Ribavirin with either standard or pegylated interferon to treat recurrent

hepatitis C after liver transplantation. Aliment Pharmacol Ther 2007; 26:291-303



3. Speranta Iacob, Liana Gheorghe, Doina Hrehoret, Gabriel Becheanu, Vlad Herlea, Irinel Popescu.

Pegylated Interferon α-2a and Ribavirin Combination Therapy in HCV Liver Transplant

Recipients. Experience of 7 Cases. J Gastrointestin Liver Dis 2008; 17:165-172

4. Iacob S, Gheorghe L, Iacob R, Gheorghe C, Hrehoret D, Popescu I. MELD exceptions and new

predictive score of death on long waiting lists for liver transplantation. Chirurgia (Bucur)

2009;104: 267-273

5. Beckebaum S, Iacob S, Klein CG, Dechêne A, Varghese J, Baba HA, Sotiropoulos GC, Paul A,

Gerken G, Cicinnati VR. Assessment of Allograft Fibrosis by Transient Elastography and

Noninvasive Biomarker Scoring Systems in Liver Transplant Patients. Transplantation.

2010;89:983-93

6. Beckebaum S, Iacob S, Sweid D, Sotiropoulos GC, Saner F, Kaiser G, Radtke A, Klein CG, Erim

Y, de Geest S, Paul A, Gerken G, Cicinnati VR. Efficacy, safety, and immunosuppressant

adherence in stable liver transplant patients converted from a twice-daily tacrolimus-based

regimen to once-daily tacrolimus extended-release formulation. Transpl Int 2011;24:666-75

7. Iacob S, Cicinnati VR, Dechêne A, Lindemann M, Heinemann FM, Rebmann V, Ferencik S,

Sotiropoulos GC, Popescu I, Horn PA, Gerken G, Paul A, Beckebaum S. Genetic, immunological

and clinical risk factors for biliary strictures following liver transplantation. Liver Int. 2012;

32(8):1253-61

8. Xu L, Beckebaum S, Iacob S, Wu G, Kaiser GM, Radtke A, Liu C, Kabar I, Schmidt HH, Zhang

X, Lu M, Cicinnati VR. MicroRNA-101 inhibits human hepatocellular carcinoma progression

through EZH2 downregulation and increased cytostatic drug sensitivity. J Hepatol. 2014;

60(3):590-8

9. Iacob S, Cicinnati VR, Lindemann M, Heinemann FM, Radtke A, Kaiser GM, Kabar I, Schmidt

HH, Baba HA, Beckebaum S. Donor-Specific Anti-HLA Antibodies and Endothelial C4d

Deposition-Association With Chronic Liver Allograft Failure. Transplantation. 2015;

99(9):1869-75

10. Iacob S, Ester C, Lita M, Ratziu V, Gheorghe L. Real-life perception and practice patterns of

NAFLD/NASH in Romania: results of a survey completed by 102 board-certified

gastroenterologists. J Gastrointestin Liver Dis. 2016;25(2):183-90

II. Teza de Doctorat:

Titlul Tezei de Doctorat: „Hepatita recurenta C posttransplant hepatic – strategii terapeutice si factori

asociati cu recurenta severa”. Coordonator: Prof. Dr. Irinel Popescu

III. Carti si Capitole din Carti:

1. Diculescu M, Iacob S, Iacob R. Manifestări extraintestinale în Boala Crohn. In Boala Crohn în practica

clinică. Sub redactia Diculescu M, Bucureşti. Cartea Universitară 2003: 263-280. ISBN 973-7956-33-8

2. Diculescu M., Iacob S. - Clinical manifestations. In : M. Diculescu, ed. Crohn’s disease in clinical

practice. Bucharest. Universitary Book Co. 2003: 75-90

3. Diculescu M., Iacob S. – Particular psychosocial aspects in Crohn’s disease. In : M. Diculescu, ed.

Crohn’s disease in clinical practice. Bucharest. Universitary Book Co. 2003: 308-324

4. S. Iacob. Fibroscan – a non-invasive method for selection of patients for treatment. In: L. Gheorghe, C.

Gheorghe. Ed. Actualitati in hepatita C. Celsius 2006: 32-39

5. S. Iacob. Is infection with hepatitis C virus a hepatic metabolic disease? In: L. Gheorghe, C. Gheorghe.

Ed. Actualitati in hepatita C. Celsius 2006: 70-81



6. Iacob S, Iacob R. Boala Wilson si sarcina (Wilson disease and Pregnancy). In: 501 intrebari despre

patologia digestiva in sarcina. Sub red. Gheorghe L, Gheorghe C. Ed. Celsius 2008: 258-271

7. Popescu I, Iacob S, Iacob R. Ulcerul gastric si duodenal. In: Irinel Popescu, ed. Tratat de Chirurgie,

volumul VIII, Partea IB, Chirurgie Generala. Editura Academiei Romane, Bucuresti 2008:1407-1430; ISBN: 973-

973-27-1679-3

8. Liana Gheorghe, Speranta Iacob. Infecţia virală C în stadiile terminale ale bolii hepatice şi la transplantaţi.

Actualitati in diagnosticul si tratamentul hepatitelor cornice virale. Editura Medicala Universitara “Iuliu

Hatieganu” Cluj Napoca 2008

9. Speranta Iacob, Liana Gheorghe. Transplantul hepatic: alocarea organelor pre- si post-introducerea

scorului MELD. In: Dan Olteanu, Miora Rizescu, eds. Caiete de Gastroenterologie si Hepatologie. Editura Semne,

Bucuresti 2008: 468-477

10. Liana Gheorghe, Irma Eva Csiki, Speranta Iacob, Cristian Gheorghe, Loredana Regep. Prevalenta

infectiei virale C in Romania: Proiectii de viitor. In: M. Grigorescu, C. Stanciu, eds. Actualitati in diagnosticul si

tratamentul hepatitelor cornice virale. Editura Medicala Universitara “Iuliu Hatieganu” Cluj Napoca 2009: 11-24

11. Cristian Gheorghe, Liana Gheorghe, Speranta Iacob. Evaluarea pre-terapeutica a pacientilor cu hepatita

cronica C: de la diagnostic la factori de esec. In: M. Grigorescu, C. Stanciu, eds. Actualitati in diagnosticul si

tratamentul hepatitelor cornice virale. Editura Medicala Universitara “Iuliu Hatieganu” Cluj Napoca 2009: 25-36

12. Liana Gheorghe, Speranta Iacob. Factori asociati cu lipsa de raspuns la terapia antivirala in infectia virala

C – o noua abordare. In: M. Grigorescu, C. Stanciu, eds. Actualitati in diagnosticul si tratamentul hepatitelor

cornice virale. Editura Medicala Universitara “Iuliu Hatieganu” Cluj Napoca 2010: 54-67

13. Iacob S, Gheorghe L, Popescu I. Management of recurrent HCV infection following liver transplantation.

In: Cernescu C, Ruta S, Gheorghe L, Iacob S, Popescu I, Wanless RS. Hepatitis C treatment. Flying Publisher

2011: 75-100

14. Gheorghe L, Iacob S. Antiviral therapy in non-responders, relapsers and special populations. In: Cernescu

C, Ruta S, Gheorghe L, Iacob S, Popescu I, Wanless RS. Hepatitis C treatment. Flying Publisher 2011: 43-57

15. Iacob S. Concepte de baza in imunologia transplantului hepatic. In: Popescu I. Transplantul hepatic.

Editura Academiei Romane, Bucuresti 2011:41-50

16. Gheorghe L, Iacob S. Selectia pacientilor pentru transplant hepatic. Obiective, indicatii si contraindicatii.

In: Popescu I. Transplantul hepatic. Editura Academiei Romane, Bucuresti 2011:51-64

17. Iacob S, Gheorghe L. Sisteme de scorificare pentru prioritizarea pacientilor pentru transplant hepatic.

Modele de prognostic. In: Popescu I. Transplantul hepatic. Editura Academiei Romane, Bucuresti 2011:65-72

18. Gheorghe L, Iacob S. Recidiva afectiunilor primare post-transplant hepatic. In: Popescu I. Transplantul

hepatic. Editura Academiei Romane, Bucuresti 2011:329-348

19. Tomescu D, Gheorghe L, Iacob S, Popescu I. Aspecte organizatorice si legislative. In: Tomescu D.

Insuficienta hepatica acuta. Editura Academiei Romane, Bucuresti 2016:185-205

20. Liana Gheorghe, Luminita Voroneanu, Speranta Iacob. Epidemiologia hepatitelor virale. In: Covic A,

Apetrii M, Trifan A, Singeap AM. Conexiuni renale in boli hepatice. Editura “Gr. T. Popa” UMF Iasi, 2017:9-29

21. Iacob Speranta, Gheorghe Liana. Transplantul hepatic. In: Gastroenterologie si Hepatologie Clinica.

Editura Medicala Bucuresti, 2018:756-768

22. Gheorghe Liana, Iacob Speranta. Hepatita cronica B. In: Gastroenterologie si Hepatologie Clinica.


23. Gheorghe Liana, Iacob Speranta. Hepatita cronica C. In: Gastroenterologie si Hepatologie Clinica.




24. Gheorghe Liana, Iacob Speranta. Hepatita cronica cu virus Delta (D). In: Gastroenterologie si

Hepatologie Clinica. Editura Medicala Bucuresti, 2018:537-546

25. Gheorghe Liana, Iacob Speranta. Hepatita autoimuna. In: Gastroenterologie si Hepatologie Clinica.


IV. Articole /studii in extenso publicate in reviste cotate ISI

1. Gheorghe L, Iacob S, Gheorghe C, Iacob R, Simionov I, Vadan R, Becheanu G, Parvulescu I, Toader C.

Frequency and predictive factors for overlap syndrome between autoimmune hepatitis and primary cholestatic

liver disease. European Journal of Gastroenterology and Hepatology 2004; June,16 (6):585-592.

2. Gheorghe C, Pascu O, Gheorghe L, Iacob R, Dumitru E, Tantau M, Vadan R, Goldis A, Balan G, Iacob S,

Dobru D, Saftoiu A. Epidemiology of inflammatory bowel disease in adults who refer to gastroenterology care

in Romania: a multicentric study. European Journal of Gastroenterology and Hepatology 2004; November, 16

(11):1153-9.

3. Gheorghe L, Popescu I, Iacob R, Iacob S, Gheorghe C. Predictors of death on the waiting list for liver

transplantation characterized by a long waiting time. Transpl Int. 2005 May;18(5):572-6.

4. Gheorghe C, Gheorghe L, Iacob S, Iacob R, Popescu I. Primary prophylaxis of variceal bleeding in

cirrhotics awaiting liver transplantation. Hepatogastroenterology 2006. Jul-Aug;53(70):552-7.

5. Gheorghe L, Iacob S, Sporea I, Grigorescu M, Sirli R, Damian D, Gheorghe C, Iacob R. Efficacy,

tolerability and predictive factors for early and sustained virologic response in patients treated with weight-

based dosing regimen of PegIFN -2b and ribavirin in real-life healthcare setting. J Gastrointestin Liver Dis

2007; 16(1):23-29

6. Iacob S, Cicinnati V, Hilgard P, Iacob R, Gheorghe L, Popescu I, Frilling A, Malago M, Gerken G,

Broelsch CE, Beckebaum S. Predictors of graft and patient survival in HCV recipients - model to predict HCV

cirrhosis following liver transplantation. Transplantation 2007; 84:56-63

7. Gheorghe L, Iacob S, Iacob R, Gheorghe C, Popescu I. Variation of the MELD score as a predictor of

death on the waiting list for liver transplantation. J Gastrointestin Liver Dis 2007; 16(3):267-272

8. Cicinnati VR, Iacob S, Klein CG, Baba HA, Sotiropoulos GC, Hilgard P, Erim Y, Broelsch CE, Gerken G,

Beckebaum S. Ribavirin with either standard or pegylated interferon to treat recurrent hepatitis C after liver

transplantation. Aliment Pharmacol Ther 2007; 26:291-303

9. Popescu I, Dima S, Guja C, Gheorghe L, Iacob S, Hrehoret D, Matei E, Dorobantu B, Botea F, Sarbu V,

Tulbure D, Ionescu-Tirgoviste C. Combined liver and islet transplantation using steroid-free

immunossupression. Chirurgia (Bucur) 2007;102:597-602

10. Gheorghe C, Iacob R, Gheorghe L, Cotruta B, Bancila I, Iacob S, Bucur D, Voinea D, Popescu I. Projected

Dynamics of Colonoscopic Screening and Surveillance for Colorectal Cancer. Hepato-Gastroenterology 2008;

55:1568-1572

11. Speranta Iacob, Liana Gheorghe, Doina Hrehoret, Gabriel Becheanu, Vlad Herlea, Irinel Popescu.

Pegylated Interferon α-2a and Ribavirin Combination Therapy in HCV Liver Transplant Recipients.

Experience of 7 Cases. J Gastrointestin Liver Dis 2008; 17:165-172

12. Gheorghe L, Iacob S, Csiki IE. Prevalence of hepatitis C in Romania: Different from European rates? J

Hepatol 2008; 49(4):661-2

13. Gheorghe L, Iacob S, Gheorghe C. Real-time sonoelastography – a new application in the field of liver

disease. J Gastrointestin Liver Dis. 2008;17(4):469-74

14. Iacob S, Hrehoret D, Matei E, Dorobantu B, Gangone E, Gheorghe L, Popescu I. Costs and efficacy of

"on demand" low-dose immunoprophylaxis in HBV transplanted patients: experience in the Romanian

program of liver transplantation. J Gastrointestin Liver Dis. 2008;17(4):383-8.

15. Gheorghe L, Iacob S, Grigorescu M, Sporea I, Sirli R, Damian D, Gheorghe C, Iacob R. High sustained

virological response rate to combination therapy in genotype 1 patients with histologically mild hepatitis C. J

Gastrointestin Liver Dis 2009;18:51-56



16. Iacob R, Sirbu-Boeti P, Iacob S, Dima S, Gheorghe C, Gheorghe L; Popescu I. Stem cell therapies for

gastrointestinal and liver diseases. Chirurgia (Bucur) 2009;104: 131-140.

17. Iacob S, Gheorghe L, Iacob R, Gheorghe C, Hrehoret D, Popescu I. MELD exceptions and new predictive

score of death on long waiting lists for liver transplantation. Chirurgia (Bucur) 2009;104: 267-273

18. Gheorghe L, Iacob S, Iacob R, Dumbrava M, Becheanu G, Herlea V, Gheorghe C, Lupescu I, Popescu I.

Real Time Elastography – a noninvasive diagnostic method of small hepatocellular carcinoma in cirrhosis. J

Gastrointestin Liver Dis 2009;18 (4):439-446

19. Popescu I, Habib N, Dima S, Hancu N, Gheorghe L, Iacob S, Mihaila M, Dorobantu B, Matei E, Botea F.

Domino liver transplantation using a graft from a donor with familial hypercholesterolemia: seven-yr follow-

up. Clinical Transplant 2009;23:565-570

20. Dima S, Iacob S, Botea F, Matei E, Brasoveanu V, Hrehoret D, Vasile S, Alexandrescu S, Croitoru A,

Dumitrascu T, Herlea V, Popescu I. Multimodal Treatment of Hepatocellular carcinoma: An Eastern European

Experience. Hepato-Gastroenterology 2009; 56 (96):1696-1703

21. Iacob S, Cicinnati VR, Beckebaum S. Current immunosuppressive approaches in liver transplantation.

Panminerva Med 2009;51:215-25

22. Beckebaum S, Iacob S, Klein CG, Dechêne A, Varghese J, Baba HA, Sotiropoulos GC, Paul A, Gerken G,

Cicinnati VR. Assessment of Allograft Fibrosis by Transient Elastography and Noninvasive Biomarker

Scoring Systems in Liver Transplant Patients. Transplantation. 2010;89:983-93

23. Popescu I, Ionescu M, Brasoveanu V, Hrehoret D, Matei E, Dorobantu B, Zamfir R, Alexandrescu S,

Grigorie M, Tulbure D, Popa L, Ungureanu M, Tomescu D, Droc G, Popescu H, Cristea A, Gheorghe L, Iacob

S, Gheorghe C, Boros M, Lupescu I, Vlad L, Herlea V, Croitoru M, Platon P, Alloub A. Liver transplantation -

indications, surgical technique, results - the analysis of a clinical series of 200 cases. Chirurgia 2010;105:177-

186

24. Gheorghe L, Pascu O, Ceausu E, Csiki IE, Iacob S, Caruntu F, Simionov I, Vadan R. Access to

Peginterferon plus Ribavirin therapy for hepatitis C in Romania between 2002-2009. J Gastrointestin Liver

Dis 2010; 19:161-167

25. Shen Q, Cicinnati V, Zhang X, Iacob S, Weber F, Sotiropoulos G, Radtke A, Lu M, Paul A, Gerken G,

Beckebaum S. Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular

carcinoma invasion. Molecular Cancer 2010, 9:227

26. Sporea I, Sirli R, Curescu M, Gheorghe L, Popescu A, Bota S, Iacob S. Outcome of antiviral treatment in

patients with chronic genotype 1 HCV hepatitis. A retrospective study in 507 patients. J Gastrointestin Liver

Dis. 2010;19(3):261-4.

27. Gheorghe L, Csiki IE, Iacob S, Gheorghe C, Smira G, Regep L. The prevalence and risk factors of

hepatitis C virus infection in adult population in Romania: a nationwide survey 2006 – 2008. J Gastrointestin

Liver Dis. 2010;19(4):373-9.

28. Beckebaum S, Iacob S, Sweid D, Sotiropoulos GC, Saner F, Kaiser G, Radtke A, Klein CG, Erim Y, de

Geest S, Paul A, Gerken G, Cicinnati VR. Efficacy, safety, and immunosuppressant adherence in stable liver

transplant patients converted from a twice-daily tacrolimus-based regimen to once-daily tacrolimus extended-

release formulation. Transpl Int 2011;24:666-75

29. Gheorghe L, Iacob S, Simionov I, Vadan R, Constantinescu I, Caruntu F, Sporea I, Grigorescu M. Weight-

based dosing regimen of Peg-Interferon α-2b for chronic hepatitis delta: a multicenter Romanian trial. J

Gastrointestin Liver Dis. 2011;20(4):377-82

30. Gologan S, Iacob R, Preda C, Vadan R, Cotruta B, Catuneanu AM, Iacob S, Constantinescu I,

Gheorghe L, Iobagiu S, Gheorghe C, Diculescu M. Higher Titers of Anti–Saccharomyces Cerevisiae

AntibodiesIgA and IgG are Associated with More Aggressive Phenotypes in Romanian Patients with

Crohn’s Disease. J Gastrointestin Liver Dis. 2012 Mar;21(1):39-44.

31. Iacob R, Iacob S, Nastase A, Vagu C, Ene AM, Constantinescu A, Anghel D, Banica C, Paslaru L, Coriu

D, Dima S, Gheorghe C, Ionica E, Gheorghe L. The His1069Gln mutation in the ATP7B gene in Romanian

http://www.ncbi.nlm.nih.gov/pubmed/?term=Iacob%20R%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Iacob%20S%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Nastase%20A%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Vagu%20C%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Ene%20AM%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Constantinescu%20A%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Anghel%20D%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Banica%20C%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Paslaru%20L%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Coriu%20D%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Coriu%20D%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Dima%20S%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Gheorghe%20C%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Ionica%20E%5BAuthor%5D&cauthor=true&cauthor_uid=22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Gheorghe%20L%5BAuthor%5D&cauthor=true&cauthor_uid=22720308



patients with Wilson's disease referred to a tertiary gastroenterology center. J Gastrointestin Liver Dis. 2012

Jun;21(2):181-5.

32. Iacob S, Cicinnati VR, Dechêne A, Lindemann M, Heinemann FM, Rebmann V, Ferencik S, Sotiropoulos

GC, Popescu I, Horn PA, Gerken G, Paul A, Beckebaum S. Genetic, immunological and clinical risk factors

for biliary strictures following liver transplantation. Liver Int. 2012; 32(8):1253-61

33. Gologan S, Iacob R, Iancu D, Iacob S, Cotruta B, Vadan R, Catuneanu AM, Constantinescu I, Barbarii L,

Gheorghe C, Diculescu M. Inflammatory gene expression profiles in Crohn's disease and ulcerative colitis: a

comparative analysis using a reverse transcriptase multiplex ligation-dependent probe amplification protocol. J

Crohns Colitis. 2013 Sep;7(8):622-30.

34. Iacob R, Iacob S, Gheorghe L, Gheorghe C, Hrehoreţ D, Brașoveanu V, Croitoru A, Herlea V, Popescu I.

Outcome of liver transplantation for hepatocellular carcinoma -- a single center experience. Chirurgia (Bucur).

2013 Jul-Aug;108(4):446-50.

35. Gheorghe C, Pascu O, Iacob R, Vadan R, Iacob S, Goldis A, Tantau M, Dumitru E, Dobru D, Miutescu E,

Saftoiu A, Fraticiu A, Tomescu D, Gheorghe L. Nutritional risk screening and prevalence of malnutrition on

admission to gastroenterology departments: a multicentric study. Chirurgia (Bucur). 2013 Jul-Aug;108(4):535-

41.

36. Gheorghe L, Iacob S, Iacob R, Smira G, Pietrareanu C, Hrehoret D, Brasoveanu V, Gheorghe C, Popescu

I. Dynamics of the Romanian waiting list for liver transplantation after changing organ allocation policy. J

Gastrointestin Liver Dis. 2013 Sep;22(3):299-303.

37. Gheorghe L, Csiki IE, Iacob S, Gheorghe C. The prevalence and risk factors of hepatitis B virus infection

in an adult population in Romania: a nationwide survey. Eur J Gastroenterol Hepatol. 2013;25(1):56-64

38. Beckebaum S, Iacob S, Radtke A, Kabar I, Cicinnati VR. Body weight may not be sufficient for reliable

estimation of subcutaneous hepatitis B immunoglobulin dose requirement. Am J Transplant. 2013;13(6):1615-

6.

39. Xu L, Beckebaum S, Iacob S, Wu G, Kaiser GM, Radtke A, Liu C, Kabar I, Schmidt HH, Zhang X, Lu M,

Cicinnati VR. MicroRNA-101 inhibits human hepatocellular carcinoma progression through EZH2

downregulation and increased cytostatic drug sensitivity. J Hepatol. 2014; 60(3):590-8

40. Gheorghe L, Iacob S, Simionov I, Caruntu F, Motoc A, Arama V, Preotescu L, Stefan I, Goldis A, Brisc C,

Rugina S, Rednic N. A real life boceprevir use in treatment-experienced HCV genotype 1 patients with

advanced fibrosis. J Gastrointestin Liver Dis. 2014 ;23(1):45-50

41. Tugui L, Dumitru M; Iacob S, Gheorghe L, Preda C, Dinu I, Becheanu G, Dumbrava M, Nicolae I, Andrei

A, Lupu A, Diculescu M. The efficacy of the Peginterferon treatment in chronic hepatitis HDV and

compensate liver cirrhosis. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi

2014;118(2):368-75

42. Iacob S, Cicinnati VR, Lindemann M, Heinemann FM, Radtke A, Kaiser GM, Kabar I, Schmidt HH,

Baba HA, Beckebaum S. Donor-Specific Anti-HLA Antibodies and Endothelial C4d Deposition-Association

With Chronic Liver Allograft Failure. Transplantation. 2015 Sep;99(9):1869-75

43. Gheorghe L, Csiki IE, Iacob S, Gheorghe C, Trifan A, Grigorescu M, Motoc A, Suceveanu A, Curescu M,

Caruntu F, Sporea I, Brisc C, Rogoveanu I, Cerban R, Tugui L, Alexandrescu A. Hepatitis Delta Virus

Infection in Romania: Prevalence and Risk Factors. J Gastrointestin Liver Dis. 2015;24(4):413-21.

44. Iacob S, Ester C, Lita M, Ratziu V, Gheorghe L. Real-life perception and practice patterns of

NAFLD/NASH in Romania: results of a survey completed by 102 board-certified gastroenterologists. J

Gastrointestin Liver Dis. 2016;25(2):183-90

45. I. Sporea, R. Lupușoru, R. Mare, A. Popescu, L. Gheorghe, S. Iacob, R. Șirli. Dynamics of liver stiffness

values by means of transient elastography in patients with HCV liver cirrhosis undergoing interferon free

treatment. J Gastrointestin Liver Dis. 2017;26(2):145-50

46. L. Gheorghe, I. Sporea, S. Iacob, R. Şirli, A. Trifan, D. Dobru, M. Diculescu, C. Stanciu, O. Pascu, M.

Acalovschi, C. Brisc, C. Cijevschi, C. Gheorghe, Z. Spârchez, I. Rogoveanu, D. Dumitrascu. Position paper on

http://www.ncbi.nlm.nih.gov/pubmed/22720308

http://www.ncbi.nlm.nih.gov/pubmed/?term=Gologan%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23014361


http://www.ncbi.nlm.nih.gov/pubmed/?term=Iancu%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23014361


http://www.ncbi.nlm.nih.gov/pubmed/?term=Cotruta%20B%5BAuthor%5D&cauthor=true&cauthor_uid=23014361

http://www.ncbi.nlm.nih.gov/pubmed/?term=Vadan%20R%5BAuthor%5D&cauthor=true&cauthor_uid=23014361

http://www.ncbi.nlm.nih.gov/pubmed/?term=Catuneanu%20AM%5BAuthor%5D&cauthor=true&cauthor_uid=23014361

http://www.ncbi.nlm.nih.gov/pubmed/?term=Constantinescu%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23014361

http://www.ncbi.nlm.nih.gov/pubmed/?term=Barbarii%20L%5BAuthor%5D&cauthor=true&cauthor_uid=23014361


http://www.ncbi.nlm.nih.gov/pubmed/?term=Diculescu%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23014361







http://www.ncbi.nlm.nih.gov/pubmed/?term=Hrehore%C5%A3%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23958083

http://www.ncbi.nlm.nih.gov/pubmed/?term=Bra%C8%99oveanu%20V%5BAuthor%5D&cauthor=true&cauthor_uid=23958083

http://www.ncbi.nlm.nih.gov/pubmed/?term=Croitoru%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23958083

http://www.ncbi.nlm.nih.gov/pubmed/?term=Herlea%20V%5BAuthor%5D&cauthor=true&cauthor_uid=23958083

http://www.ncbi.nlm.nih.gov/pubmed/?term=Popescu%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23958083



http://www.ncbi.nlm.nih.gov/pubmed/?term=Pascu%20O%5BAuthor%5D&cauthor=true&cauthor_uid=23958098


http://www.ncbi.nlm.nih.gov/pubmed/?term=Vadan%20R%5BAuthor%5D&cauthor=true&cauthor_uid=23958098


http://www.ncbi.nlm.nih.gov/pubmed/?term=Goldis%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23958098

http://www.ncbi.nlm.nih.gov/pubmed/?term=Tantau%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23958098

http://www.ncbi.nlm.nih.gov/pubmed/?term=Dumitru%20E%5BAuthor%5D&cauthor=true&cauthor_uid=23958098

http://www.ncbi.nlm.nih.gov/pubmed/?term=Dobru%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23958098

http://www.ncbi.nlm.nih.gov/pubmed/?term=Miutescu%20E%5BAuthor%5D&cauthor=true&cauthor_uid=23958098

http://www.ncbi.nlm.nih.gov/pubmed/?term=Saftoiu%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23958098

http://www.ncbi.nlm.nih.gov/pubmed/?term=Fraticiu%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23958098

http://www.ncbi.nlm.nih.gov/pubmed/?term=Tomescu%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23958098






http://www.ncbi.nlm.nih.gov/pubmed/?term=Smira%20G%5BAuthor%5D&cauthor=true&cauthor_uid=24078987

http://www.ncbi.nlm.nih.gov/pubmed/?term=Pietrareanu%20C%5BAuthor%5D&cauthor=true&cauthor_uid=24078987

http://www.ncbi.nlm.nih.gov/pubmed/?term=Hrehoret%20D%5BAuthor%5D&cauthor=true&cauthor_uid=24078987

http://www.ncbi.nlm.nih.gov/pubmed/?term=Brasoveanu%20V%5BAuthor%5D&cauthor=true&cauthor_uid=24078987






http://www.jgld.ro/wp/archive/y2017/n2/a10






treatment of hepatitis C in Romania, 2017. Part one. J Gastrointestin Liver Dis. 2017;26(2):171-81

(Corresponding author)

47. Gheorghe L, Sporea I, Iacob S, Sirli R, Trifan A, Diculescu M, Stanciu C, Pascu O, Acalovschi M, Brisc

C, Cijevschi C, Gheorghe C, Spârchez Z, Rogoveanu I, Dobru D, Dumitrascu DL. Position Paper on

Treatment of Hepatitis C in Romania 2017. Part Two. J Gastrointestin Liver Dis. 2017;26(3):309-317.

(Corresponding author)

48. Gheorghe L, Iacob S, Curescu M, Brisc C, Cijevschi C, Caruntu F, Stanciu C, Simionov I, Sporea I,

Gheorghe C, Iacob R, Arama V, Sirli R, Trifan A. Real-Life Use of 3 Direct-Acting Antiviral Regimen in a

Large Cohort of Patients with Genotype-1b HCV Compensated Cirrhosis. J Gastrointestin Liver Dis.

2017;26(3):275-281. (Corresponding author)

49. Dorobantu B, Popescu I, Dima S, Nastase A, Iacob S. Molecular Biomarkers as Predictors for Biliary

Complications Following Liver Transplantation. A Prospective Study. J Gastrointestin Liver Dis.

2017;26(3):253-259.

50. Trifan A, Stanciu C, Gheorghe L, Iacob S, Curescu M, Prelipcean Cijevschi C, Stefanescu G, Girleanu I,

Chiriac S, Mihai C, Brisc C, Goldis A, Sporea I, Miftode E, Bataga S, Rogoveanu I, Preda C, Caruntu FA,

Singeap AM. Efficacy and safety of paritaprevir/ritonavir, ombitasvir, and dasabuvir wiith ribavirin for the

treatment of HCV genotype 1b compensated cirrhosis in patients aged 70 years or older. Medicine

2017;96:50-55

51. Ricco G, Popa DC, Cavallone D, Iacob S, Salvati A, Tabacelia D, Oliveri F, Mascolo G, Bonino F,

Yuan Q, Xia NS, Gheorghe L, Brunetto MR. Quantification of serum markers of hepatitis B (HBV) and

Delta virus (HDV) infections in patients with chronic HDV infection. J Viral Hepat. 2018; 25(8):911-919

52. Iacob S, Cerban R, Pietrareanu C, Ester C, Iacob R, Gheorghe C, Popescu I, Gheorghe L. 100% Sustained

Virological Response and Fibrosis Improvement in Real-Life Use of Direct Acting Antivirals in Genotype-1b

Recurrent Hepatitis C following Liver Transplantation. J Gastrointestin Liver Dis. 2018;27(2):139-144

53. Ester C, Cerban R, Iacob S, Pietrareanu C, Constantin G, Paslaru L, Ichim S, Lita M, Vadan R, Grancea C,

Ruta S, Gheorghe C, Popescu I, Gheorghe L. The Role of Beta-7 Integrin and Carbonic Anhydrase IX in

Predicting the Occurrence of de Novo Nonalcoholic Fatty Liver Disease in Liver Transplant Recipients.

Chirurgia (Bucur). 2018;113(4):534-541

54. Cerban R, Ester C, Iacob S, Paslaru L, Dumitru R, Grasu M, Constantin G, Popescu I, Gheorghe L.

Evaluation of Tumor Response Using Alpha-fetoprotein and Des-gamma-carboxy Prothrombin in

Hepatocellular Carcinoma Patients Who Underwent Transarterial Chemoembolization. Chirurgia (Bucur).

2018;113(4):524-533.

55. Razvan Cerban, Carmen Ester, Speranta Iacob, Mugur Grasu, Liliana Pâslaru, Radu Dumitru, Ioana

Lupescu, Georgiana Constantin, Adina Croitoru, Liana Gheorghe. Predictive Factors of Tumor Recurrence and

Survival in Patients with Hepatocellular Carcinoma treated with Transarterial Chemoembolization. J

Gastrointestin Liver Dis 2018; 27:409-417

56. Jercan A, Badelita S, Draghici M, Stoica E, Iacob S, Coriu D. Clinical manifestations in hereditary

amyloidosis with the variant Glu54Gln transthyretin. Amyloid 2019; 26(S1):31-32

V. Articole /studii publicate in extenso in jurnale indexate BDI

1. Diculescu M, Apriotesei R, Zâmbreanu L, Iacob S, Iacob R, Oproiu A. Recent developments in

pathophysiology and medical treatment of portal hypertension. Annals of Fundeni Hospital 1999. 4 (3-4): 109-

114.

2. Diculescu M, Iacob S, Iacob R, Sclifos D, Ionescu R, Oproiu A. Is oral bile acid dissolution a better

alternative to laparoscopic cholecystectomy for patients with gallbladder stones? Annals of Fundeni Hospital

2001. 6(1): 18-27




3. Diculescu M, Iacob R, Iacob S, Croitoru A, Becheanu G, Popeneciu V. The Importance of

Histopathological and Clinical Variables in Predicting the Evolution of Colon Cancer. Rom J Gastroenterol

2002 Sep;11(3):183-9

4. Gheorghe C, Gheorghe L, Iacob R, Iacob S, Simionov I, Bancila I. Argon Plasma Coagulation for

Radiation Proctitis. Rom J Gastroenterol 2003 June; 12(2):107-112

5. Vadan R, Gheorghe L, Becheanu G, Iacob R., Iacob S, Gheorghe C. Predictive factors for the severity of

liver fibrosis in patients with chronic hepatitis C and moderate alcohol consumption. Rom J Gastroenterol 2003

Sep; 12(3):183-187

6. Gheorghe L, Iacob S, Bolog N, Stoicescu A, Parvulescu I, Popescu I. – Overlap syndrome between

autoimmune hepatitis and primary biliary cirrhosis complicated by hepatocellular carcinoma. Case report -

Romanian Journal of Gastroenterology 2004 March; 13 (1):33-8.

7. Gheorghe L, Popescu I, Iacob S, Gheorghe C, Vadan R, Constantinescu A, Iacob R, Becheanu G,

Angelescu C, Diculescu M. Wilson’s disease: a challenge of diagnosis. The 5-years experience of a tertiary center.

Rom J Gastroenterol 2004 September; 13 (3): 179-185.

8. Diculescu M, Iacob R, Chira C, Mihaila D, Iacob S. Esomeprazole in the treatment of patients with

heartburn and other upper gastrointestinal symptoms, referred to primary care -- results of the in-practice

evaluation program in Romania. Rom J Gastroenterol. 2005 Mar;14(1):9-14.

9. Gheorghe L, Grigorescu M, Iacob S, Damian D, Gheorghe C, Iacob R, Simionov I, Vadan R, Parvulescu I,

Bancila I. Effectiveness and tolerability of pegylated Interferon alpha-2a and ribavirin combination therapy in

Romanian patients with chronic hepatitis C: from clinical trials to clinical practice. Rom J Gastroenterol. 2005

Jun;14(2):109-15.

10. Gheorghe L, Iacob R, Vadan R, Iacob S, Gheorghe C. Improvement of hepatic encephalopathy using a

modified high-calorie high-protein diet. Rom J Gastroenterol. 2005 Sep;14(3):231-8.

11. Gheorghe L, Iacob S, Simionov I, Vadan R, Gheorghe C, Iacob R, Parvulescu I, Constantinescu I. Natural

history of compensated viral B and D cirrhosis. Rom J Gastroenterol. 2005 Dec;14(4):329-35.

12. Iacob R, Iacob S, Gheorghe L, Gheorghe C, Diculescu M. The use of IT in the medical system has

economic and research advantages--the experience of Fundeni Gastroenterology and Hepatology Center. Rom J

Gastroenterol. 2005 Dec;14(4):426-9.

13. Popescu I, Tulbure D, Gheorghe L, Hrehoret D, Popa L, Iacob S, Malago M. Emergency protocol for an

adult ABO-incompatible living related liver transplantation. Annals of Fundeni Hospital 2006;10:49-56

14. Gheorghe L, Iacob S, Gheorghe C, Herlea V, Becheanu G, Ardeleanu C, Dumbrava M, Lupescu I,

Popescu I. Ecoendoscopic elastography for the diagnosis of hepatocellular carcinoma in small cirrhotic nodules.

Archives of the Balkan Medical Union 2007; 42:186-188

15. Gheorghe L, Iacob S, Lupescu I, Popescu H, Budai A. Percutaneous radiofrequency ablation for

hepatocellular carcinoma. Archives of the Balkan Medical Union 2008; 43:66-67

16. Tugui L, Iacob S, Gheorghe L, Preda C, Vadan R, Simionov I, Andrei A, Fulger L, Diculescu M, Dumitru

M. Influence of hepatitis delta virus infection on natural history of compensated viral B cirrhosis. Practica

Medicala 2014; 9(3):151-156

17. Iacob S, Gheorghe L, Tabacelia D, Iacob R, Gheorghe C, Popescu I. A new score to predict outcome after

liver transplantation. J Transl Med Res 2015; 20(3):123-131

18. Iacob Razvan, Herlea Vlad, Popa Codruta, Nastase Anca, Ghetea Ligia, Iacob Speranta, Botea Florin,

Pechianu Catalin, Grigorie Razvan, Croitoru Adina, Dima Simona, Gheorghe Cristian, Gheorghe Liliana and

Popescu Irinel. Prognostic significance of CD44 expression in hepatocellular carcinoma following a potentially

curative treatment. J. Transl. Med. Res 2016;21(4):267-273

19. Popescu I, Ionescu M, Braşoveanu V, Hrehoreţ D, Copca N, Lupaşcu C, Botea F, Dorobanţu B,

Alexandrescu S, Grigorie M, Matei E, Zamfir R, Lungu V, Tomescu D, Droc G, Ungureanu D, Fota R, Manga G,

Popescu M, Popa L, Gheorghe L, Iacob S, Pietrăreanu C, Mihailă M, Mic L, Constantinescu S, Gheorghe C,

Cotruta B, Lupescu I, Grasu M, Boroş M, Dumitru R, Toma M, Paslaru L, Vlad L, Constantinescu I, Dima I,

Herlea V, Becheanu G, Pecheanu C, Sasalovici D. The Romanian National Program for Liver Transplantation -

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Gheorghe+L%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Grigorescu+M%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Iacob+S%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Damian+D%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Gheorghe+C%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Iacob+R%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Simionov+I%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Vadan+R%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Parvulescu+I%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Bancila+I%22%5BAuthor%5D








http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Simionov+I%22%5BAuthor%5D




http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Parvulescu+I%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Constantinescu+I%22%5BAuthor%5D





http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Diculescu+M%22%5BAuthor%5D



852 Procedures in 815 Patients over 17 Years (2000-2017): A Continuous Evolution to Success. Chirurgia

(Bucur). 2017;112(3):229-243

20. Cerban R, Croitoru A; Becheanu G; Popescu I; Lupescu I; Botea F; Iacob S; Herlea V; Pietrareanu C;

Dumitru R; Gheorghe C; Gheorghe L.. Management of hepatic epithelioid haemangioendothelioma: 5 year single-

center experience and literature review. Open J Clin Med Case Rep. 2017; 1294.

21. Tudoroiu MI, Constantin G, Paslaru L, Iacob S, Gheorghe C, Popescu I, Tomescu D, Gheorghe LS. The

Combination of serum Cystatin C, urinary kidney molecule 1, and MELD Plus score predicts early acute kidney

injury after liver transplantation. Surg Gastroenterol Oncol 2018; 23(6):109-114 (Corresponding author)

22. Carmen Ester, Razvan Cerban, Speranta Iacob, Corina Pietrareanu, Mihaela Lita, Olteanu Ovidiu-Andrei,

Simona Ichim, Georgiana Constantin, Liliana Paslaru, Camelia Grancea, Simona Ruta, Liana Gheorghe.

Metabolic Syndrome and Cardiovascular Risk in Liver Transplant Recipients - Can Non-invasive Testing Change

the Landscape? Surg Gastroenterol Oncol 2018; 23(6):386-390

23. Razvan Cerban, Carmen Ester, Speranta Iacob, Mihaela Ghioca, Liliana Paslaru, Dumitru Radu, Mugur

Grasu, Georgiana Constantin, Irinel Popescu, Liliana Gheorghe. Evaluation of Alpha-fetoprotein and Prothrombin

Induced by Vitamin K Absence for Hepatocellular Carcinoma Diagnosis in Patients Admitted to a Large

Transplant Center. Surg. Gastroenterol. Oncol. 2018;23(6):391-398

VI. Articole /studii publicate in extenso cu caracter educational

1. Diculescu M, Iacob S, Iacob R. Acidul ursodeoxicolic în bolile hepatice colestatice cronice. Revista

pentru Educatie Medicala Continua – Gastroenterologie 2002. 1(3): 85 – 91.

2. A. Ionescu, L. Gheorghe, C. Gheorghe, S. Iacob. Gastroenterology and Hepatology Quiz (H-Q 21): Budd-

Chiari syndrome. Romanian J Gastroenterology 2003;12(3):247-249

3. S. Iacob, L. Gheorghe, G. Becheanu, R. Iacob. Gastroenterology and Hepatology Quiz (H-Q 25):

Association of Wilson disease and HBV infection. Rom J Gastroenterol 2004; 13(3):254-6

4. C. Gheorghe, L. Gheorghe, G. Becheanu, R. Iacob, S. Iacob. Gastroenterology and Hepatology Quiz (H-Q

26): Peptic esophagitis. Rom J Gastroenterol 2004; 13(4):349-50

5. L. Gheorghe, S. Iacob. ESPEN guide for the evaluation of nutrition status 2002. Romanian J

Gastroenterology 2004;13(1):66-73

6. S. Iacob, L. Gheorghe. Advances in the chronic viral hepatitis and hepatocellular carcinoma. Viata

Medicala 2004; no. 15/9 aprilie: pagina 12

7. R. Iacob, S. Iacob, M. Diculescu. Actual indications of antibiotics and probiotics in the treatment of

chronic inflammatory bowel disease. Gastro.ro Nr 2/ 2005

8. L. Gheorghe, S. Iacob, C. Gheorghe, G. Becheanu. Gastroenterology and Hepatology Quiz (H-Q 27):

Antiviral therapy for AgHBe (-) HBV chronic hepatitis. Romanian J Gastroenterol 2005; 13: 90-91

9. Liana Gheorghe, Speranta Iacob, Cristian Gheorghe. Gastroenterology and Hepatology Quiz (H-Q 29):

Profilaxy of hepatitis B infection. Rom J Gastroenterol 2005; 14: 308-309

10. Liana Gheorghe, Speranta Iacob, Cristian Gheorghe, Ioana Lupescu. Gastroenterology and Hepatology

Quiz (H-Q 33): Upper gastrointestinal bleeding caused by extrahepatic portal vein obstruction. J Gastrointest Liver

Dis 2006; 15: 280-282

11. Iacob S, Iacob R. Boala Wilson si sarcina.Revista pentru educatie Medicala Continua. Gastroenterologie

2007. 6(2):69-74

12. Iacob S, Gheorghe L, Popescu I. Rolul polimorfismului genei IL 28 B la pacientii cu hepatita cronica C.

Viata Medicala 2011; no. 12/25 martie: pagina 6

VII. Rezumate ale lucrarilor prezentate la conferinte internationale de specialitate, publicate in reviste

cotate ISI

1. Diculescu M, Iacob R, Iacob S, Croitoru A. Evaluation of colonic cancer prognostic factors in a five years

https://www.ncbi.nlm.nih.gov/pubmed/28675359

https://www.ncbi.nlm.nih.gov/pubmed/28675359



prospective study: univariate analysis. Hepato-Gastroenterology 2001; 48 (Suppl I): CLXX

2. Diculescu M, Iacob R, Iacob S. Oral bile acids dissolution – an alternative to laparoscopic

cholecystectomy for a better quality of life for patients with gallbladder stones. Hepato-Gastroenterology 2001; 48

(Suppl I): CLXXI

3. Diculescu M, Iacob R, Iacob S. Predictive factors of spontaneous bacterial peritonitis: results of a case-

control study. Hepato-Gastroenterology 2001; 48 (Suppl I): CLXXIV

4. Diculescu M, Iacob S, Iacob R, Oproiu A. Alternative treatment regimens and predictive markers of

interferon monotherapy failure in patients with chronic hepatitis C. Journal of Hepatology 2001; 34 (Suppl 1):144

5. Diculescu M, Iacob S, Iacob R, Arbanas T, Becheanu G. Is the activity degree linked to other phatological

and individual features of chronic gastritis? Hepato-Gastroenterology 2002; 49 (Suppl II): CCXLI

6. Diculescu M, Iacob R, Iacob S, Arbanas T, Croitoru A, Becheanu G. The features of patients with Dukes

B colonic cancer, with implications in early diagnosis. Hepato-Gastroenterology 2002; 49 (Suppl II): CCLIX

7. Iacob R, Iacob S, Arbanas T, Atanasiu C, Diculescu M, Croitoru A, Becheanu G. Survival in patients with

colonic cancer according to the extent of intestinal wall invasion. Hepato-Gastroenterology 2002; 49 (Suppl

II):CCLIX

8. Iacob R, Iacob S, Diculescu M. Predictive factors of spontaneous bacterial peritonitis: univariate and

multivariate analysis. Journal of Hepatology 2002; 36 (Suppl 1): 54

9. Iacob S, Iacob R, Diculescu M. Predictive markers of therapy outcome in chronic hepatitis C. Journal of

Hepatology 2002; 36 (Suppl 1): 111

10. Iacob R, Iacob S, Diculescu M. What can be done for patients with chronic hepatitis C which have failed

to respond to interferon monotherapy? Journal of Hepatology 2002; 36 (Suppl 1): 112

11. Iacob R, Iacob S, Diculescu M. Ursodeoxycholic acid in the treatment of gallbladder lithiasis – a meta-

analysis. Journal of Hepatology 2002; 36 (Suppl 1): 141

12. Iacob R, Iacob S, Croitoru A, Luca I, Jarcău R, Diculescu M, Becheanu G, Gheorghe C, Gheorghe L,

Popescu I. Which histopathological and clinical variables are best for predicting the evolution of non-metastased

colon cancer? Annals of Oncology 2003; 14 (Suppl 3): III47

13. R. Iacob, S. Iacob, L. Gheorghe, M. Diculescu, C. Gheorghe, I. Constantinescu, A. Ionescu, M. Ciocirlan.

The side effects profile and tolerability of Peginterferon alpha-2a in combination with RBV compared to

conventional Interferon alpha-2a and RBV in patients with chronic hepatitis C. Gut 2003; 52 (Suppl VI):A 104

14. L. Gheorghe, S. Iacob, R. Iacob, C. Gheorghe, A. Stoicescu, I. Popescu. Predictors of death on a waiting

list for liver transplantation in Romania. Gut 2003; 52 (Suppl VI):A 160

15. C. Gheorghe, R. Iacob, L. Gheorghe, S. Iacob, I. Simionov, I. Bancila. Argon plasma coagulation in the

treatment of radiation proctitis – what power setting to choose? Gut 2003; 52 (Suppl VI):A 188

16. S. Iacob, R. Iacob, M. Diculescu, L. Gheorghe, I. Simionov, R. Vadan, I. Stanel. A rapid diagnostic test for

HBV infection: efficacy and advantages. Hepato-Gastroenterology 2003; 50 (Suppl I): CLII (P75)

17. I.Parvulescu, S. Iacob, R. Iacob, L. Gheorghe. MELD, Child-Pugh and Maddrey scores in assessing the

prognosis of patients with alcoholic hepatitis superimposed on alcoholic cirrhosis. Hepato-Gastroenterology 2003;

50 (Suppl I): CXXVI (P127)

18. S. Iacob, L. Gheorghe, R. Iacob, C. Gheorghe, A. Stoicescu, I. Popescu. An alternative model to predict

survival for patients on the waiting list for liver transplantation useful in the case of long waiting period. Hepato-

Gastroenterology 2003; 50 (Suppl I): CXXIX (P7136)

19. C. Gheorghe, R. Iacob, I. Bancila, N. Zamfirescu, L. Gheorghe, S. Iacob, R. Brescan, C. Popescu, C.

Zaharia. Efficacy and complications of endoscopic dilation in achalasia. Hepato-Gastroenterology 2003; 50 (Suppl

I): CXXXIV (P41)

20. R. Iacob, C. Gheorghe, M. Diculescu, S. Iacob, L. Gheorghe. Pros and cons of band ligation versus

sclerotherapy in the treatment of variceal bleeding. Hepato-Gastroenterology 2003; 50 (Suppl I): CXXXV (P43)

21. R. Vadan, L. Gheorghe, M. Badea, S. Iacob, C. Gheorghe. The prevalence and risk factors for malnutrition

in patients with cirrhosis. Clinical Nutrition 2004; 23: 872 (04-A-622-ESPEN)

22. L. Gheorghe, S. Iacob, C. Gheorghe, R. Vadan, R. Iacob, A. Constantinescu, C. Angelescu, I. Popescu.



Diagnosis of Wilson’s disease: still a challenge. Gut 2004; 53 (Suppl VI) A91 (MON-G-94)

23. R. Iacob, G. Becheanu, M. Dumbrava, S. Iacob, L. Gheorghe, C. Gheorghe. Concordance between three

histologic scoring systems used for the evaluation of chronic hepatitis C. Gut 2004; 53 (Suppl VI) A173 (TUE-G-

93)

24. C. Gheorghe, R. Iacob, I. Bancila, G. Becheanu, L. Gheorghe, S. Iacob. Small colorectal advanced

adenomas: what incidence and associated risk factors? Gut 2004; 53 (Suppl VI) A268 (WED-G-187)

25. C. Gheorghe, R. Iacob, L. Gheorghe, S. Iacob, R. Vadan, M. Diculescu, A. Goldis, E. Dumitru, D. Dobru,

E. Miutescu, A. Saftoiu, A. Fraticiu, O. Pascu. Prevalence of malnutrition and risk factors in patients with liver

diseases referred to tertiary gastroenterology assistance: a multicentric study. Journal of Gastroenterology and

Hepatology 2004; 19 (Suppl) A799

26. L. Gheorghe, S. Iacob, R. Iacob, C. Gheorghe. Natural history of compensated hepatitis B and D virus

related cirrhosis. J Gastroenterol Hepatol 2004; 19 (Suppl) A806

27. S. Iacob, L. Gheorghe, A. Istrate, R. Crintea, R. Iacob, C. Gheorghe. Predictive factors of non-neoplastic

portal vein thrombosis in cirrhotic patients. J Hepatol 2005; 42 (Suppl 2): 81

28. C. Gheorghe, S. Iacob, I. Bancila, L. Gheorghe, R. Iacob, M. Fleancu, C. Marica Changing epidemiologic

pattern of gastric pattern in Romania. Hepato-Gastroenterology 2005; 52 (Suppl 1): A86

29. C. Gheorghe, S. Iacob, L. Gheorghe, R. Iacob, I. Popescu. Risk factors for colorectal polyps in cirrhotic

patients included on the waiting list for liver transplantation. Hepato-Gastroenterology 2005; 52 (Suppl 1): A135

30. C. Gheorghe, L. Gheorghe, S. Iacob, R. Iacob. Malnutrition as a risk factor for bleeding after endoscopic

band ligation in patients with liver cirrhosis. Clinical Nutrition 2005; 24: 619 (P168)

31. C. Gheorghe, S. Iacob, L. Gheorghe, R. Iacob. Is cirrhosis a risk factor for colorectal polyps? Prospective

study in patients included on the waiting list for liver transplantation. Gut 2005; 54 (Suppl VII): A194

32. R. Iacob, J. Quinton, F. Guillemot, F. Pattou, I. Bancila, C. Gheorghe, S. Iacob, L. Gheorghe, M.

Diculescu. Esophageal manometry abnormalities after gastric banding for morbid obesity. Gut 2005; 54 (Suppl

VII): A14

33. S. Iacob, L. Gheorghe, C. Gheorghe, R. Iacob, D. Bucur, A. Croitoru. Predictors of hepatocellular

carcinoma occurrence in patients with cirrhosis. Hepatology 2005; 42 (Suppl 1): 396A

34. S. Iacob, S. Beckebaum, R. Iacob, V. Cicinnati, C. Klein, L. Gheorghe, C. Gheorghe, I. Popescu, A.

Frilling, M. Malago, G. Gerken, C. Broelsch. A model to predict one year graft failure in patients transplanted for

HCV cirrhosis. Journal of Hepatology 2006; 44 (Suppl 2): S62 (Abstract#144)

35. S. Iacob, S. Beckebaum, V. Cicinnati, R. Iacob, L. Gheorghe, C. Gheorghe, I. Popescu, A. Frilling, M.

Malago, G. Gerken, C. Broelsch. Predictive factors of sustained virological and histological response after

combined antiviral therapy in transplanted patients with recurrent hepatitis C. Journal of Hepatology 2006; 44

(Suppl 2): S215 (Abstract#580)

36. S. Iacob, S. Beckebaum, V. Cicinnati, R. Iacob, C. Klein, L. Gheorghe, C. Gheorghe, I. Popescu, A.

Frilling, M. Malago, G. Gerken, C. Broelsch. Protective factors for severe recurrence of hepatitis C after liver

transplantation. Gastroenterology 2006; 130 (Suppl 2): A-79 (Abstract 541)

37. S. Iacob, S. Beckebaum, R. Iacob, V. Cicinnati, C. Klein, L. Gheorghe, C. Gheorghe, I. Popescu, A.

Frilling, M. Malago, G. Gerken, C. Broelsch. Predictive factors for graft and patient survival following liver

transplantation for hepatitis C. Gastroenterology 2006; 130 (Suppl 2): A-500: (Abstract T1221)

38. R. Iacob, I. Bancila, C. Gheorghe, D. Bucur, D. Voinea, S. Iacob, L. Gheorghe, A. Croitoru, I. Ciurea, M.

Manuc, D. Pitigoi, M. Diculescu, I. Popescu. The Prospective evaluation of resources needed for colonoscopic

surveillance of patients with curative resection for colorectal cancer, in a romanian gastroenterology referral center

– data of Colocans registry. Gut 2006; 55 (Suppl V): A188

39. S. Iacob, R. Iacob, Liana Gheorghe, C. Gheorghe, I. Popescu. Prediction of death on the waiting list for

liver transplantation based on MELD score variation. Gastroenterology 2007 (Suppl 2); 132: A672 (Abstract

#W1157)

40. R. Iacob, I. Vartan, L. Gheorghe, B. Cotruta, S. Iacob, L. Tugui, I. Bancila, C. Gheorghe. Clinical and

demographic features in patients with familial adenomatous polyposis registered in gastroenterology and



Hepatology Center Fundeni. Journal of Gastrointestinal and Liver Diseases 2007; 16 (Suppl 1): 49

41. R. Iacob, C. Baceanu, I. Parvulescu, R. Vadan, B. Cotruta, S. Iacob, L. Gheorghe, C. Gheorghe, M.

Diculescu. Modalities of phenotipic presentation of patients with intestinal inflammatory bowel diseases.

Generation of the IBDPROSPECT registry. Journal of Gastrointestinal and Liver Diseases 2007; 16 (Suppl 1): 56

42. S. Iacob, L. Gheorghe, D. Hrehoret, R. Iacob, C. Gheorghe, I Popescu. Antiviral therapy in patients with

recurrent hepatitis C after liver transplantation. Journal of Gastrointestinal and Liver Diseases 2007; 16 (Suppl 1):

71

43. L. Gheorghe, S. Iacob, B. Cotruta, R. Iacob, A. Carabelea, C. Gheorghe. Screening of cirrhotic patients

and incidence of hepatocellular carcinoma nodules. Journal of Gastrointestinal and Liver Diseases 2007; 16 (Suppl

1): 6

44. C. Gheorghe, B. Cotruta, V. Herlea, A. Carabelea, G. Becheanu, R. Iacob, I. Bancila, S. Iacob, L.

Gheorghe. Gastrointestinal stromal tumors: prevalence, clinical presentation and management. Journal of

Gastrointestinal and Liver Diseases 2007; 16 (Suppl 1): 25

45. C. Gheorghe, B. Cotruta, R. Iacob, I. Pirvulescu, S. Iacob, I. Bancila, L. Gheorghe. Extrahepatic portal

vein thrombosis in the absence of hepatic cirrhosis: etiology and clinical presentation. Journal of Gastrointestinal

and Liver Diseases 2007; 16 (Suppl 1): 27

46. N. Zamfirescu, S. Iacob, L. Gheorghe, C. Gheorghe, C. Gheorghe, I. Simionov, I. Pirvulescu, R. Vadan, C.

Angelescu, G. Becheanu, M. Dumbrava. Predictive factors of anemia due to combined therapy with pegylated

interferon and ribavirin in patients with chronic hepatitis C. Journal of Gastrointestinal and Liver Diseases 2007;

16 (Suppl 1): 72

47. B. Cotruta, L. Gheorghe, V. Trifu, C. Cotruta, S. Iacob, G. Becheanu, R. Vadan, A. Carabelea, C.

Gheorghe. Acute neutrophilic dermatosis (SWEET syndrome) - a new adverse event due to antiviral therapy with

interferon – case presentation. Journal of Gastrointestinal and Liver Diseases 2007; 16 (Suppl 1): 72

48. L. Gheorghe, S. Iacob. Referral for liver transplantation: MELD and beyond. Hepatogastroenterology

2007; 54 (Suppl 1): A24

49. L. Gheorghe, S. Iacob, M. Dumbrava, G. Becheanu, R. Iacob, B. Cotruta, A. Carabelea, C. Gheorghe.

Sonoelastographic evaluation of small hepatocellular carcinoma in cirrhotic patients – a pilot study.

Hepatogastroenterology 2007; 54 (Suppl 1): A98

50. C. Gheorghe, B. Cotruta, V. Herlea, M. Mihai, C. Ardeleanu, G. Becheanu, R. Iacob, I. Bancila, S. Iacob,

L. Gheorghe. Gastrointestinal stromal tumors: The prevalence, clinical presentation and outcome.


51. R. Iacob, I. Vartan, L. Gheorghe, B. Cotruta, S. Iacob, L. Tugui, I. Bancila, M. Ionescu, I. Popescu, C.

Gheorghe. Familial polyposis syndromes registry – screening, diagnosis, treatment and follow-up.


52. B. Cotruta, C. Gheorghe, L. Gheorghe, R. Iacob, I. Parvulescu, S. Iacob, I. Bancila. Non-cirrhotic, non-

neoplastic extrahepatic portal vein thrombosis: etiology, presentation and management. Hepatogastroenterology

2007; 54 (Suppl 1): A248

53. S. Iacob, L. Gheorghe, M. Grigorescu, I. Sporea, R. Vadan, I. Parvulescu, R. Sirli, D. Damian. Antiviral

therapy in mild chronic hepatitis C: beyond “Watch and wait” strategy. Hepatogastroenterology 2007; 54 (Suppl

1): A165

54. S. Iacob, R. Iacob, L. Gheorghe, C. Gheorghe, I. Popescu. MELD score variation: predictor of death on

waiting list for liver transplantation. Transpl Int 2007; 20 (Suppl 2): 260

55. S. Iacob, S. Beckebaum, R. Iacob, V. Cicinnati, C. Klein, L. Gheorghe, C. Gheorghe, A. Frilling, M.

Malago, I. Popescu, G. Gerken, C. Broelsch. Recurrent HCV cirrhosis prediction model in liver transplant

recipients. Transpl Int 2007; 20 (Suppl 2): 288

56. I. Popescu, D. Tulbure, L. Gheorghe, M. Mihaila, D. Hrehoret, V. Brasoveanu, V. Vidu, E. Matei, S. Iacob,

S. Dima. Five years follow-up of a patient with domino liver transplantation for familial hypercholesterolemia.

Transpl Int 2007; 20 (Suppl 2): 301

57. Cicinnati VR, Klein CG, Iacob S, Baba H, Sotiropoulos G; Hilgard P, Erim Y; Broelsch CE; Gerken, G,



Beckebaum, S. Interferon-alpha and combined with ribavirin in HCV liver transplant recipients: Efficacy and

predictors of response. Z Gastroenterol 2007; 45:A3_09.

58. Diculescu M, Iacob R, Constantinescu I, Toader A, Cotruta B, Baceanu C, Parvulescu I, Vadan R, Iacob S,

Gheorghe L, Gheorghe C, Preda C. ASCA and ANCA serology in Romanian IBD patients. Journal of Crohn’s and

Colitis 2008; 2:90 (P291)

59. Gheorghe L, Iacob S, Iacob R, Becheanu G, Dumbrava M, Gheorghe C, Simionov I, Lupescu I, Popescu I.

Real-time elastography – a pilot study for non-invasive detection of small hepatocellular carcinoma in cirrhotic

patients. Gastroenterology 2008

60. Gheorghe L, Iacob S, Lupescu I, Becheanu G, Dumbrava M. Real-time elastography – a useful method for

the detection of hepatocellular carcinoma in small cirrhotic nodules. J Hepatol 2008; 48 (Suppl 2):S115 (P287)

61. Iacob S, Gheorghe L, Grigorescu M, Sporea I, Simionov I, Pirvulescu I, Vadan R, Becheanu G. Predictive

factors of sustained viral response in patients with mild hepatitis C. J Hepatol 2008; 48 (Suppl 2):S297 (P796)

62. Gheorghe L, Iacob S, Lupescu I, Becheanu G, Dumbrava M, Iacob R, Gheorghe C, Popescu I. Early and

non-invasive diagnosis of small hepatocellular carcinoma using real-time elastography. Ultraschall in der Med

2008; 29 (Suppl 1): S4 (OP 1.16)

63. Iacob R, Diculescu M, Constantinescu I, Toader A, Cotruta B, Baceanu C, Gologan S, parvulescu I, Vadan

R, Iacob S, Gheorghe L, Gheorghe C, Preda C. ASCA and ANCA serology in Romanian IBD patients. Journal of


64. Gheorghe L, Iacob S, Becheanu G, Dumbrava M, Iacob R. Noninvasive real-time elastographic evaluation

of patients with chronic hepatitis C. Journal of Gastrointestinal and Liver Diseases 2008; 17 (Suppl 1):100

65. Gheorghe L, Iacob S, Grigorescu M, Sporea I, Sirli R, Damian D, Gheorghe C, Iacob R. Should we treat

patients with mild hepatitis C? – Yes of course! Journal of Gastrointestinal and Liver Diseases 2008; 17 (Suppl 1):

128

66. Gheorghe L, Iacob S, Iacob R, Becheanu G, Dumbrava M, Gheorghe C, Lupescu I, Popescu I. Real-time

elastography – a non-invasive diagnostic tool of small hepatocellular carcinoma in cirrhotic patients. Journal of


67. Iacob S, Gheorghe L, Iacob R, Becheanu G, Herlea V, Hrehoret D, Gheorghe C, Popescu I. Noninvasive

elastographic evaluation of the patients with recurrent hepatitis C following liver transplantation. Journal of


68. Gheorghe L, Iacob S, Iacob R, Gheorghe C, Popescu I. Prediction of death on large waiting lists for liver

transplantation using MELD exceptions. Journal of Gastrointestinal and Liver Diseases 2008; 17 (Suppl 1): 176

69. Iacob S, Gheorghe L, Hrehoret D, Iacob R, Becheanu G, Herlea V, Gheorghe C, Popescu I. Patient and

graft survival following liver transplantation for HCV liver cirrhosis – predictive factors identified in the

Romanian Transplant Program. Journal of Gastrointestinal and Liver Diseases 2008; 17 (Suppl 1): 177

70. Iacob S, Gheorghe L, Constantinescu A, Iacob R, Cerban R, Gheorghe C, Popescu I. Wilson’s disease –

type of presentation and outcomes of treatment – experience of a tertiary centre. Journal of Gastrointestinal and

Liver Diseases 2008; 17 (Suppl 1): 202

71. Gheorghe L, Csiki I, Iacob S, Trifan A, Stanciu C, Regep L. Hepatitis B virus infection epidemiology in

Romania. Journal of Gastrointestinal and Liver Diseases 2008; 17 (Suppl 1): 79

72. Smira G, Mavrogenis G, Gheorghe L, Csiki I, Iacob S, Pirvulescu I, Trifan A, Stanciu C, Regep L. The

prevalence of anti-hepatitis B core antibodies in Romania. Journal of Gastrointestinal and Liver Diseases 2008; 17

(Suppl 1): 81

73. Gheorghe L, Csiki I, Iacob S, Trifan A, Stanciu C, Regep L. Hepatitis C virus infection epidemiology in

Romania. Journal of Gastrointestinal and Liver Diseases 2008; 17 (Suppl 1): 85

74. Iacob S, Hrehoret D, Matei E, Dorobantu B, Gangone E, Gheorghe L, Popescu I. “On demand” low-dose

HBIG administration and recurrence rates in HBV transplanted patients. Journal of Gastrointestinal and Liver

Diseases 2008; 17 (Suppl 1): 172

75. Savoiu D, Gheorghe L, Iacob S, Popa L, Popescu I. Acute hepatic failure – first manifestation of Wilson

disease. Journal of Gastrointestinal and Liver Diseases 2008; 17 (Suppl 1): 178



76. Iacob S, Hrehoret D, Dorobantu B, Gangone E, Iacob R, Gheorghe L, Popescu I. Minimal costs and

efficacy of immunoprophylaxis in HBV transplanted patients – experience in the Romanian program of liver

transplantation. Transplantation 2008; 86 (2S): 427

77. Iacob S, Gheorghe L, Iacob R, Becheanu G, Herlea V, Hrehoret D, Gheorghe C, Popescu I. Real-time

elastography and histological evaluation in patients with recurrent hepatitis C following liver transplantation.

Transplantation 2008; 86 (2S): 427

78. Iacob S, Gheorghe L, Iacob R, Gheorghe C, Popescu I. Can MELD exceptions predict death on large

waiting lists? Transplantation 2008; 86 (2S): 667

79. Popescu I, Dima S, Hancu N, Gheorghe L, Iacob S, Mihaila M, Matei E, Dorobantu B, Botea F. Six-year

follow-up of a domino liver transplantation using a graft from a donor with familial hypercholesterolemia.

Transplantation 2008; 86 (2S): 668

80. Iacob R, Iancu D, Iacob S, Cotruta B, Baceanu C, Gheorghe C, Gheorghe L, Iobagiu S, Barbarii L,

Diculescu M. Multiplex ligation-dependent probe amplification (MLPA) inflammatory gene expression profiling

in patients with inflammatory bowel disease. Hepato-Gastroenterology 2008; 55 (Suppl I): A339 (P558)

81. Gheorghe L, Iacob S, Iacob R, Becheanu G, Dumbrava M. Real – time elastography – a novel approach to

assess liver fibrosis in patients with chronic hepatitis C. Hepato-Gastroenterology 2008; 55 (Suppl I): A73

(OP178)

82. Gheorghe C, Iacob S, Cotruta B, Iacob R, Gheorghe L, Becheanu G, Dumbrava M, Suciu S, Bancila I,

Popescu I. Prevalence of clinically significant histology in small colonic neoplastic polyps. Hepato-

Gastroenterology 2008; 55 (Suppl I):A162 (P125) 83. Diculescu M, Iacob R, Iancu D, Barbarii L, Iacob S, Cotruta B, Gologan S, Baceanu C, Catuneanu A,

Gheorghe C, Gheorghe L, Iobagiu S. Inflammatory genes expression profiles in patients with IBD investigated

using multiplex ligation –dependent probe amplification (MLPA). Journal of Crohn’s and Colitis 2009; 3 (1):S100

(P227)

84. Diculescu M, Iacob R, Iancu D, Barbarii L, Cotruta B, Iacob S, Gologan S, Baceanu C, Catuneanu A,

Gheorghe C, Gheorghe L, Iobagiu S. Extra-intestinal manifestations in IBD are associated with specific mucosal

inflammatory genes expression profiles. Journal of Crohn’s and Colitis 2009; 3 (1):S115 (P264)

85. Iacob R, Diculescu M, Constantinescu I, Toader A, Cotruta B, Gologan S, Baceanu C, Vadan R, Iacob S,

Gheorghe C, Gheorghe L, Iobagiu S, Preda C. ASCA Ig A and Ig G titers predict Crohn’s disease phenotype in

Romanian patients. Journal of Crohn’s and Colitis 2009; 3 (1):S121 (P282)

86. Iacob R, Iancu D, Barbarii L, Constantinescu I, Toader A, Cotruta B, Iacob S, Gologan S, Baceanu C,

Vadan R, Gheorghe L, Gheorghe C, Iobagiu S, Diculescu M. Model de predictie a bolii Crohn severe utilizand

profilul de expresie mucozala a genelor inflamatorii si titrul ASCA. Journal of Gastrointestinal and Liver Diseases

2009; 18 (Suppl 1): 11

87. Iacob S, Dima S, Matei E, Tanase A, Herlea V, Croitoru A, Iacob R, Gheorghe L, Gheorghe C, Popescu I.

Factori de risc ai recurentei carcinomului hepatocelular dupa tratamentul chirurgical. Journal of Gastrointestinal


88. Gheorghe L, Iacob S, Dumbrava M, Becheanu G, Iacob R, Gheorghe C, Simionov I, Vadan R.

Elastografia in timp real – un prim pas catre biopsia hepatica virtuala in hepatita cronica virala C. Journal of


89. Gheorghe L, Iacob S, Iacob R, Becheanu G, Dumbrava M, Herlea V, Gheorghe C, Lupescu I, Popescu I.

Elastografia in timp real poate prezice prezenta hepatocarcinomului precoce la pacientii cirotici. Journal of


90. Gheorghe L, Iacob S, Onu M, Iacob R, Lupescu I, Gheorghe C. Analiza semiautomata computerizata a

imaginilor obtinute la ecografia cu contrast pentru diagnosticul leziunilor focale maligne la pacientii cirotici.

Journal of Gastrointestinal and Liver Diseases 2009; 18 (Suppl 1): 96

91. Diculescu M, Iacob R, Iancu D, Barbarii L, Iacob S, Cotruta B, Gologan S, Baceanu C, Catuneanu A,

Gheorghe C, Gheorghe L, Iobagiu S. Investigarea profilului de expresie a genelor implicate in procesele

inflamatorii la pacientii cu IBD, utilizand tehnica MLPA (multiplex ligation-dependent probe amplification).



Journal of Gastrointestinal and Liver Diseases 2009; 18 (Suppl 1): 110

92. Gheorghe L, Csiki I, Iacob S, Gheorghe C, Smira G, Regep L. Prevalenta si factorii de risc ai infectiei cu

virus hepatitic B in Romania. Journal of Gastrointestinal and Liver Diseases 2009; 18 (Suppl 1): 12

93. Gheorghe L, Csiki I, Iacob S, Gheorghe C, Smira G, Regep L. Estimarea complicatiilor pe termen lung ale

infectiei cu VHC in Romania. Journal of Gastrointestinal and Liver Diseases 2009; 18 (Suppl 1): 60

94. Sporea I, Sirli R, Curescu M, Gheorghe L, Iacob S, Bota S, Popescu A, Danila M. Raspunsul viral sustinut

intr-o serie de pacienti cu hepatita cronica VHC tratati cu PegInterferon si Ribavirina. Journal of Gastrointestinal



virus hepatitic C in Romania. Journal of Gastrointestinal and Liver Diseases 2009; 18 (Suppl 1): 75

96. Iacob S, Dima S, Matei E, Iacob R, Gheorghe L, Gheorghe C, Popescu I. Usefulness of staging systems

for hepatocellular carcinoma in predicting recurrence after surgical therapy. Gut 2009; 58 (Suppl II):A486

97. R. Iacob, D. Iancu, L. Barbarii, I. Constantinescu, A. Toader, B. Cotruta, S. Iacob, S. Gologan, C. Baceanu,

R. Vadan, L. Gheorghe, C. Gheorghe, S. Iobagiu, M. Diculescu. Model to Predict Crohn's Disease Behaviour

Using Mucosal Inflammatory Genes Expression Profile and ASCA Titers. Gastroenterology 2009. 136(5); S1:

A260

98. Beckebaum S, Iacob S, Klein C, Dechene A, Varghese J, Baba H, Sotiropoulos G, Paul A, Gerken G,

Cicinnati V. Non-invasive assessment of severe fibrosis in patients transplanted for non-HCV related liver

diseases. Transplant International 2009; 22 (Suppl 2):365 (Late breaking abstract)



diseases. Transplantationmedizin 2009; Suppl 2: S17

100. Cicinnati VR, Shen Q, Iacob S, Weber F, Klein CG, Sotiropoulos GC, Radtke A, Paul A, Gerken G,

Beckebaum S. Role of microRNA-199a-5p and discoidin domain receptor 1 for human hepatocellular carcinoma

invasion. Z Gastroenterol 2010;48:P2_13.

101. Iacob S, Cicinnati VR, Dechêne A, Klein CG, Popescu I, Paul A, Gerken G, Beckebaum S. Role of

chemokine receptor and ATP-binding cassette transporter gene polymorphisms for biliary lesions following liver

transplantation. Z Gastroenterol 2010;48:P3_05.


Cicinnati VR. Efficacy of liver stiffness measurement and biochemical tests to assess severe fibrosis in patients

transplanted for non-HCV related liver diseases. Z Gastroenterol 2010;48:P3_01.

103. Iacob S, Cicinnati VR, Dechêne A, Klein CG, Popescu I, Paul A, Gerken G, Beckebaum S. Chemokine

receptor and ATP-binding cassette transporter gene polymorphisms as risk factors for anastomotic and non-

anastomotic strictures development following liver transplantation. J Hepatol 2010; 52:S61


Cicinnati VR. Transient elastography and development of a non-invasive multiparameter score for assessment of

allograft fibrosis in liver transplant patients. J Hepatol 2010; 52:S159

105. Iacob S, Cicinnati VR, Dechêne A, Klein CG, Popescu I, Paul A, Gerken G, Beckebaum S. ATP-binding

cassette transporter gene polymorphisms as independent predictive factors for severe recurrent hepatitis C after

liver transplantation. J Hepatol 2010; 52:S316

106. Shen Q, Beckebaum S, Iacob S, Weber F, Klein CG, Paul A, Gerken G, Cicinnati VR. Decreased

expression of miR-199a-5p contributes to increased cell invasion by functional deregulation of DDR1 activity in

hepatocellular carcinoma. J Hepatol 2010; 52:S336


cassette transporter gene polymorphisms and insulin resistance as risk factors for advanced fibrosis following liver

transplantation for HCV infection. Gastroenterology 2010;138 (Suppl 1):S69

108. Iacob S, Hrehoret D, Brasoveanu V, Gheorghe L, Popescu I. Survival outcomes following liver

transplantation (SOFT) score - A useful predictor of short term mortality in Romanian Liver Transplant Program.

Transplantation 2010;90(2S):833



109. Shen Q, Beckebaum S, Iacob S, Klein CG, Sotiropolous G, Radtke A, Paul A, Gerken G, Cicinnati VR.

Decreased expression of miR-199a-5p contributes to increased cell invasion by functional deregulation of DDR1

activity in hepatocellular carcinoma. Transplantation 2010;90(2S): 774

110. S. M. Iacob, V.R. Cicinnati, A. Dechene, C.G. Klein, G.C. Sotiropoulos, A. Radtke, I. Popescu, M.

Lindemann, A. Paul, G. Gerken, S. Beckebaum. Single nucleotide polymorphisms of chemokine receptors and

ATP-binding cassette transporter and risk of biliary strictures after liver transplantation. Transplantation

2010;90(2S):500

111. S.M. Iacob, V.R. Cicinnati, A. Dechene, C.G. Klein, M. Lindemann, G.C. Sotiropoulos, A. Radtke, I.

Popescu, G. Gerken, A. Paul, S. Beckebaum. Effect of MDR1 and ABCG8 polymorphisms on hepatitis C

recurrence following liver transplantation. Transplantation 2010;90(2S):126

112. S. Beckebaum, S.M. Iacob, C.G. Klein, A. Dechene, J. Varghese, H.A. Baba, G.C. Sotiropoulos, A.

Radtke, G. Gerken, A. Paul, V.R. Cicinnati. Transient elastography and development of a non-invasive

multiparameter score for assessment of allograft fibrosis in liver transplant patients. Transplantation

2010;90(2S):349

113. Iacob R, Gologan S, Iancu D, Vadan R, Cotruta B, Iacob S, Preda C, Baceanu C, Pojoga C, Iobagiu S,

Gheorghe C, Gheorghe L, Brabarii L, Diculescu M. The genetics of inflammatory bowel disease in ROMANIA –

results of the IBDPROSPECT study. Journal of Gastrointestinal and Liver Diseases 2010; 19 (Suppl 1):11

114. Gheorghe L, Simionov I, Vadan R, Pirvulescu I, Smira G, Iacob S, Carabelea A, Angelescu C, Gheorghe

C. Role of contrast enhanced ultrasound in the characterization of focal liver lesions: report of a series of 100

cases. Journal of Gastrointestinal and Liver Diseases 2010; 19 (Suppl 1): 3

115. Iacob S, Cicinnati V, Dechene A, Klein C, Popescu I, Paul A, Gerken G, Beckebaum S. Role of gene

polymorphism in hepatitis C recurrence following liver transplantation. Journal of Gastrointestinal and Liver

Diseases 2010; 19 (Suppl 1):14

116. Iacob S, Hrehoret D, Brasoveanu V, Dorobantu B, Matei E, Alexandrescu S, Zamfir R, Romanescu D,

Gheorghe L, Popescu I. MELD and SOFT scores – predictors of mortality following liver transplantation in

Romanian liver transplant program. Journal of Gastrointestinal and Liver Diseases 2010; 19 (Suppl 1):57

117. Smira G, Gheorghe L, Iacob S, Coriu D, Gheorghe C. Budd Chiari syndrome and V617F/JAK2 mutation

linked with the myeloproliferative disorders. Journal of Gastrointestinal and Liver Diseases 2010; 19 (Suppl

1):177

118. Smira G, Suciu S, Iacob S, Iacob R, Gheorghe L, Gheorghe C. Chronic administration of rifaximin for the

maintenance of remission of hepatic encephalopathy in a 6 month study. Journal of Gastrointestinal and Liver

Diseases 2010; 19 (Suppl 1):178

119. Gheorghe L, Pascu O, Ceausu E, Csiki IE, Iacob S, Caruntu F, Simionov I, Vadan R. Access to

peginterferon plus ribavirin therapy for hepatitis C in Romania between 2002-2009. Journal of Gastrointestinal and

Liver Diseases 2010; 19 (Suppl 1):180

120. Iacob S, Cicinnati V, Dechene A, Klein C, Gong M, Popescu I, Paul A, Gerken G, Beckebaum S. Altered

cytokines pattern in patients with ischemic type biliary lesions following liver transplant. Journal of

Gastrointestinal and Liver Diseases 2010; 19 (Suppl 1):182

121. Iacob S, Gheorghe L, Popescu I. Liver stiffness is influenced by cholestasis and hepatocytolisis in

recurrent hepatitis C following liver transplantation. Journal of Gastrointestinal and Liver Diseases 2010; 19

(Suppl 1):207

122. Gheorghe L, Pascu O, Ceausu E, Csiki IE, Iacob S, Caruntu F, Simionov I, Vadan R. Access to combined

antiviral therapy for hepatitis C in Romania. Gut 2010;59 (Suppl III): A45

123. Pirvulescu I, Gheorghe L, Suciu S, Gheorghe C, Iacob S, Diculescu M. The impact and the prevalence of

nonalcoholic fatty liver disease on chronic hepatitis B. Gut 2010;59 (Suppl III): A432 124. Smira G, Gheorghe C, Gheorghe L, Iacob S, Iacob R. Chronic administration of rifaximin for the

maintenance of remission of hepatic encephalopathy. Gut 2010;59 (Suppl III): A55



125. Cicinnati V, Gong M, Saner F, Iacob S, Paul A, Beckebaum S. Increased levels of interleukin 10 in serum

of patients with sepsis syndrome are associated with altered homing properties of blood myeloid dendritic cells.

Inflammation Research 2010; 59:A311

126. Cicinnati V, Saner F, Gong M, Iacob S, Paul A, Beckebaum S. Immunological and clinical biochemical

factors for survival prediction of patients with sepsis syndrome. Inflammation Research 2010; 59:A325

127. Iacob S, Gheorghe C, Iacob R, Pascu O, Gheorghe L, Goldis A, Tantau M, Dumitru E, Dobru D,

Vadan R, Saftoiu A, Bancila I, Pirvulescu I, Tugui L, Diculescu M. Prevalence of malnutrition in patients

admitted in tertiary gastroenterology centers from Romania: a multicentric study. Revista Romana de

Nutritie Clinica 2011, 8(suppl1):32-33

128. Xu L, Beckebaum S, Wu G, Zhang X, Lu M, Iacob S, Paul A, Gerken G, Cicinnati V. The putative tumor

suppressor microRNA-101 negatively regulates the polycomb group protein enhancer of zeste homolog 2 (EZH2)

in human hepatocellular carcinoma cells. J Hepatol 2011;54:S110

129. Iacob S, Cicinnnati V, Wu G, Dechene A, Popescu I, Paul A, Gerken G, Beckebaum S. Genetic

polymorphisms of ABCG5/8 and ABCB1 and their impact after liver transplantation. J Hepatol 2011;54:S224

130. Iacob S, Beckebaum S, Wu G, Dechene A, Popescu I, Paul A, Gerken G, Cicinnati V. Polymorphisms of

fractalkine receptor and immunologic risk fcators for anastomosis stenosis after liver transplantation. J Hepatol

2011;54:S278

131. Gheorghe L, Iacob S, Simionov I, Vadan R, Constantinescu I, Sporea I, Grigorescu M. Efficacy of

pegylated interferon alpha-2b in a romanian cohort with chronic hepatitis delta. J Hepatol 2011;54:S285

132. Pirvulescu I, Gheorghe L, Suciu S, Iacob S, Radu C, Gheorghe C. The prevalence and the liver stiffness

values in hepatitis D virus co-infection compared to hepatitis B virus mono-infection. Journal of Gastrointestinal

and Liver Diseases 2011; 20:56

133. Iacob S, Iacob R, Nastase A, Coriu D, Paslaru L, Popescu I, Gheorghe L. Is it possible to use IL28B gene

polymorphism for prediction of early virological response in patients with recurrent hepatitis C following liver

transplantation? Journal of Gastrointestinal and Liver Diseases 2011; 20:16

134. Gheorghe L, Iacob R, Iacob S, Nastase A, Gheorghe C, Coriu D, Paslaru L. Investigation of IL28B gene

polymorphism in Romanian chronic hepatitis C patients treated with pegylated interferon and ribavirin. Journal of

Gastrointestinal and Liver Diseases 2011; 20 suppl1:15

135. Iacob S, Iacob R, Cerban R, Smira G, Constantinescu A, Gheorghe L. Prediction of poor prognosis in

Wilson cirrhosis. Journal of Gastrointestinal and Liver Diseases 2011; 20:103

136. Gheorghe L, Gheorghe C, Smira G, Iacob S, Suciu S. Optimal donor selection for adult to adult living

donor liver transplantation in Romania. Journal of Gastrointestinal and Liver Diseases 2011; 20:104

137. Gheorghe L, Iacob S, Ghidu C, Cerban R, Simionov I, Danila M, Sporea I, Croitoru A, Croitoru M,

Hrehoret D, Popescu I. Curative and palliative therapy of hepatocellular carcinoma in patients diagnosed in tertiary

gastroenterology centers in Romania. Journal of Gastrointestinal and Liver Diseases 2011; 20:110

138. Gheorghe L, Iacob S, Simionov I, Vadan R, Constantinescu I, Caruntu F, Sporea I, Grigorescu M. Efficacy

of pegylated interferon -2b in a romanian cohort with chronic hepatitis delta. Journal of Gastrointestinal and

Liver Diseases 2011; 20:44

139. Gheorghe L, Iacob S, Simionov I, Vadan R, Constantinescu I, Sporea I, Grigorescu M. Pegylated

interferon -2b for the management of patients with chronic hepatitis delta. Gastroenterology 2011

140. Iacob S, Iacob R, Nastase A, Coriu D, Paslaru L, Popescu I, Gheorghe L. IL28B gene polymorphism for

prediction of early virological response in romanian patients with recurrent hepatitis C. Transplant International

2011; 24 (Suppl 2):263


fractalkine receptor and risk for anastomosis stenosis after liver transplantation. Transplant International 2011; 24

(Suppl 2):12

142. Iacob S, Cicinnati V, Wu G, Dechene A, Popescu I, Paul A, Gerken G Beckebaum S. ABCG5/8 and

ABCB1 polymorphisms as risk factors for advanced fibrosis following liver transplantation. Transplant

International 2011; 24 (Suppl 2):30



143. Iacob S, Cicinnati V, Dechene A, Popescu I, Paul A, Gerken G Beckebaum S. Altered cytokines pattern in

patients with ischemic type biliary lesions following liver transplantation. Transplant International 2011; 24 (Suppl

2):158

144. Iacob S, Gheorghe L, Becheanu G, Dumbrava M, Popescu I. Influence of cholestasis and hepatocytolisis

on liver stiffness in recurrent hepatitis C following liver transplantation. Transplant International 2011; 24 (Suppl

2):310

145. Iacob S, Iacob R, Cerban R, Smira G, Constantinescu A, Gheorghe L. Predictive factors of poor prognosis

in Wilson cirrhosis. Gut 2011;60 (Suppl 3):A357

146. Pirvulescu I, Gheorghe L, Iacob S, Radu C, Gheorghe C. The prevalence and the liver stiffness evaluated

by transient elastography in hepatitis D virus co-infection in comparison with hepatitis B mono-infection. Gut

2011;60 (Suppl 3):A139

147. Gheorghe C, Gheorghe L, Smira G, Iacob S, Suciu SM, Popescu I. Endoscopic colic lesions in liver

transplant candidates. Gut 2011;60 (Suppl 3):A359

148. R. Iacob, S. Iacob, A. Nastase, C. Vagu, M. Grigorie, T. Dumitrascu, A. Tanase, B. Dorobantu, L. Stoica,

L. Paslaru, D. Coriu, S. Dima, A. Croitoru, G. Smira, L. Gheorghe, I. Popescu, C. Gheorghe. Quantitative gene

expression of liver enriched transcription factors in curativelly treated hepatocellular carcinoma. Gut 2012; 61

(Suppl 3) A114

149. Iacob S, Iacob R, Grigorie M, Hrehoret D, Brasoveanu V, Herlea V, Gheorghe C, Gheorghe L, Popescu I.

Outcome of liver transplantation for hepatocellular carcinoma – a single center experience. Transplantation 2012;

94, 10S:p632

150. Iacob S, Cicinnati VR, Wu G, Lindemann M, Heinemann FM, Rebmann V, Horn PA, Kabar I, Schmidt

HH, Beckebaum S. Soluble ligands for activating natural killer receptor (NKG2D) are biomarkers for progression

of hepatic fibrosis after liver transplantation. Transplantation 2012

151. Iacob S, Cicinnati VR, Wu G, Xu L, Kabar I, Schmidt HH, Beckebaum S. Role of ATP-Binding cassette

transporter gene polymorphisms and metabolic risk factors for allograft fibrosis after liver transplantation.

Transplantation 2012

152. L. Gheorghe, S. Iacob, C. Ghidu, R. Iacob, R. Cerban, I. Simionov, A. Croitoru, C. Gheorghe, I. Popescu.

Liver stiffness value assessed by transient elastography correlates with nodule size in patients with hepatocellular

carcinoma. Gastroenterology 2012, Vol. 142, Issue 5, S-979–S-980

153. G. Smira, S. Iacob, C. Gheorghe, I. Popescu, L. Gheorghe. Adult living donor liver transplantation – how

efficient and safe is the donation ? J Hepatol 2012; 56: S94 (A222)

154. L. Gheorghe, S. Iacob, I. Simionov, R. Vadan, I. Constantinescu. Efficacy of antiviral therapy in 102

Romanian patients with chronic hepatitis delta. J Hepatol 2012; 56: S205 (A517) 155. S. Iacob, R. Iacob, A. Nastase, C. Gheorghe, D. Coriu, L. Paslaru, L. Gheorghe. IL28B CC genotype and

mild hepatitis as favorable baseline profile predicting SVR after bitherapy in naive HCV-infected patients. J

Gastrointestin Liver Dis 2012; 21 (Suppl 2): 54 (4.10)

156. R. Iacob, S. Iacob, A. Nastase, C. Vagu, M. Grigorie, T. Dumitrascu, A.M. Tanase, B. Dorobantu, L.

Stoica, L. Paslaru, D. Coriu, S. Dima, A. Croitoru, C. Gheorghe, L. Gheorghe, I. Popescu. Quantitative gene

expression of liver enriched transcription factors in curativelly treated hepatocellular carcinoma. J Gastrointestin

Liver Dis 2012; 21 (Suppl 2): 110 (6.11)

157. L. Gheorghe, S. Iacob, C. Ghidu, R. Iacob, C. Gheorghe, R. Cerban, I. Simionov, I. Sporea, M. Danila, A.

Croitoru, M. Croitoru, D. Hrehoret, and I. Popescu. Management pattern of hepatocellular carcinoma at two

tertiary centers in Romania. J Gastrointestin Liver Dis 2012; 21 (Suppl 2): 112 (6.13)

158. R. Iacob, S. Iacob, AM Ene, A. Nastase, C. Vagu, A. Constantinescu, D. Anghel, C. Banica, L. Paslaru, D.

Coriu, S. Dima, C. Gheorghe, E. Ionica, L. Gheorghe. Mutations in exon 14 and 16 of ATP7B gene, in Romanian

patients with Wilson’s disease referred to a tertiary gastroenterology center. J Gastrointestin Liver Dis 2012; 21

(Suppl 2): 139 (8.4)

159. L. Gheorghe, S. Iacob, C. Ghidu, R. Iacob, I. Simionov, A. Croitoru, C. Gheorghe, I. Popescu. Corelation

between liver stiffness and nodule size in patients with hepatocellular carcinoma. J Gastrointestin Liver Dis 2012;

https://www.ueg.eu/education/document/quantitative-gene-expression-of-liver-enriched-transcription-factors-in-curativelly-treated-hepatocellular-carcinoma/97857

https://www.ueg.eu/education/document/quantitative-gene-expression-of-liver-enriched-transcription-factors-in-curativelly-treated-hepatocellular-carcinoma/97857



21 (Suppl 2): 152 (10.4)

160. L. Gheorghe, S. Iacob, M. Greere, E. Matei, V. Brasoveanu, I. Popescu. Acute hepatitis B in a patient with

sustained virological response to antiviral therapy for recurrent hepatitis C following liver transplantation. J

Gastrointestin Liver Dis 2012; 21 (Suppl 2): 55 (4.11)

161. S. Iacob, D. Hrehoret, E. Matei, B. Dorobantu, V. Brasoveanu, M. Dumbrava, G. Becheanu, V. Herlea, I.

Popescu, L. Gheorghe. Recurrent hepatitis C following liver transplantation in the Romanian Transplant program –

treatment and outcome. J Gastrointestin Liver Dis 2012; 21 (Suppl 2): 57 (4.12)

162. G. Smira, S. Iacob, C. Gheorghe, I. Popescu, L. Gheorghe. Adult living donor liver transplantation – donor

safety experience over 8 years. J Gastrointestin Liver Dis 2012; 21 (Suppl 2): 76 (5.1)

163. S. Iacob, L. Cvas, M. Greere, R. Vadan, C. Pietrareanu, I. Simionov, L. Gheorghe. Concordance regarding

staging of fibrosis between real-time and transient elastography in chronic hepatitis B and C. J Gastrointestin Liver

Dis 2012; 21 (Suppl 2): 151 (10.3)

164. S. Iacob, R. Iacob, A. Nastase, D. Coriu, L. Paslaru, I. Popescu, L. Gheorghe. Recipint IL28B gene

polymorphism and recurrent hepatitis C following liver transplantation in Romanian patients. Liver Transpl

2012;18 (Suppl 1): S247 (P321)

165. Iacob S, Beckbaum S, Lindemann M, Heinemann FM, Rebmann V, Wu G, Schmidt HJ, Kabar I, Radtke

A, Baba HA, Cicinnati VR. Donor specific anti-MHC class II antibodies negatively impact allograft survival

following liver transplantation. J Hepatol 2013; 58:S71 (P160)

166. Gheorghe L, Csiki IE, Iacob S, Trifan A, Grigorescu M, Motoc A, Suceveanu A, Curescu M, Caruntu F,

Sporea I, Brisc C, Rogoveanu I, Tugui L, Alexandrescu A. Prevalence, virological and clinical characteristics of

chronic hepatitis delta virus infection (CHD) in Romania. J Hepatol 2013; 58:S169 (P413)

167. Iacob S, Cicinnati VR, Lindemann M, Heinemann FM, Rebmann V, Kabar I, Schmidt HJ, Radtke A,

Beckbaum S. Soluble ligands for activating natural killer receptor (NKG2D) as screening tool to predict severity

of allograft fibrosis after liver transplantation. J Hepatol 2013; 58:S169 (P721)

168. R. Iacob, C.Vagu, A. Nastase, S. Iacob, R. Grigorie, V. Herlea, A.Croitoru, S. Dima, C. Gheorghe, L.

Gheorghe, M. Ott, I. Popescu. Quantitative Gene Expression of Liver Enriched Transcription Factors Could Be

Used to Predict Tumor Recurrence After Curative Treatment of Hepatocellular Carcinoma. Gastroenterology

2013, Vol. 144, Issue 5, S-1024

169. R Iacob, C Vagu, A Nastase, S Iacob, M Grigorie, L Stoica, V Herlea, A Croitoru, S Dima, D

Coriu, L Paslaru, L Gheorghe, C Gheorghe, M Ott, I Popescu. Prediction hepatocellular carcinoma

recurrence after curative treatment using quantitative gene expression of liver enriched transcription factors.

Hepatol Int 2013. 7 (Suppl 1):S1–S754. A1522.

170. R Iacob, C Vagu, A Nastase, S Iacob, M Grigorie, L Stoica, V Herlea, A Croitoru, S Dima, D

Coriu, L Paslaru, C Gheorghe, I Popescu, L Gheorghe. Quantitative gene expression of liver progenitor

cells specific genes in curatively treated hepatocellular carcinoma. Hepatol Int 2013. 7 (Suppl 1):S1–S754.

A1245

171. R Iacob, U Ruedrich, S Iacob, C Gheorghe, L Gheorghe, S Dima, M Bock, M Ott, I Popescu.

Expression of proteins involved in intercellular junctions is strongly correlated to liver enriched

transcription factors in HUH7 hepatoma cells. Hepatol Int 2013. 7 (Suppl 1):S1–S754. A2520

172. Iacob S, Vagu C, Iacob R, Nastase A,Paslaru L, Popescu I, Ruta S, Gheorghe L. Recipient IL28B

gene polymorphism and sustained viral response in Romanian patients with recurrent hepatitis C following

liver transplantation. J Gastrointest Liver Dis 2013; Suppl 1, 22:4; OP3

173. R Iacob, C Vagu, A Năstase, S Iacob, M Grigorie, V Herlea, A Croitoru, S Dima, C Gheorghe, L

Gheorghe, M Ott, I Popescu. Quantitative gene expression of liver enriched transcription factors for

prediction of tumor recurrence after curative treatment of hepatocellular carcinoma. J Gastrointest Liver

Dis 2013; Suppl 1, 22:5; OP6

174. R. Iacob, C. Vagu, A. Nastase, S. Iacob, M. Grigorie, L. Stoica, V. Herlea, A. Croitoru, S. Dima, D.

Coriu, L. Paslaru, L. Gheorghe, I. Popescu. Quantitative gene expression of liver progenitor cells specific

genes in curatively treated hepatocellular carcinoma. J Gastrointest Liver Dis 2013; Suppl 1, 22:125; PP123



175. Tugui L, Iacob S, Gheorghe L, Preda CM, Cerban R, Becheanu G, Dumbrava M, Diculescu M.

Treatment of chronic hepatitis delta virus with Peg-Interferon. J Gastrointest Liver Dis 2013; Suppl 1,

22:125;OP40

176. Gheorghe L, Iacob S, Caruntu F, Simionov I, Motoc A, Arama V, Preotescu L, Stefan I, Goldis A. A week

8 model predicting early virologic response (EVR) and futility of boceprevir (BOC), PegInterferon (PEG) and

ribavirin (RBV) regimen. J Gastrointest Liver Dis 2013; Suppl 1, 22:125;OP60

177. R. Iacob, M.M. Diculescu, I. Constantinescu, A. Toader, B. Cotruta, S. Gologan, C. Baceanu, R. Vadan, S.

Iacob, C. Gheorghe, L. Gheorghe, S. Iobagiu, C. Preda. Extraintestinal manifestations in Romanian IBD patients

evaluation of a cohort of over 1000 patients. J Crohns Colitis 2014 http://dx.doi.org/10.1016/S1873-

9946(14)60746-7 S331.

178. L. Gheorghe, R. Iacob, S. Iacob, R. Vadan, L. Guinea, M. Greere, B. Cotruta, D. Dobru, C. Mihai, G.

Stefanescu, R. Zaharie, M. Ilie, M. Jinga, M. Diculescu, C. Gheorghe, on behalf of the IBDPROSPECT Study

Group. IBD in elderly Romanian patients: epidemiological and phenotypical characteristics. J Crohns and Colitis

2014. http://dx.doi.org/10.1016/S1873-9946(14)60740-6 S328-S329.

179. L. Gheorghe, R. Iacob, C. Vagu, A. Nastase, S. Iacob, F. Botea, V. Herlea, A. Croitoru, S. Dima, C.

Gheorghe, I. Popescu. A Predictive Score Using Quantitative Gene Expression of Stem/Liver Progenitor Cells

Specific Genes Can Be Used to Identify Patients At Risk for Tumor Recurrence in Curatively Treated

Hepatocellular Carcinoma. Gastroenterology 2014, Vol. 146, Issue 5, 356 (S-605)

180. Iacob S, Cicinnati V, Lindeman M, Heinemann F, Radtke A, Kaiser G, Kabar I, Schmidt H, Baba H,

Beckebaum S. Donor specific antibodies against HLA class II and C4D-positivity: risk factors for liver allograft

fibrosis. J Hepatol 2014 (P148)

181. Iacob S, Cerban R, Gheorghe L. Which oligosaccharide to use for minimal hepatic encephalopathy in liver

cirrhosis patients – oligofructose enriched-inulin or lactulose? J Hepatol 2014 (P462)

182. Iacob S, Cicinnati V, Kabar I, Schmidt H, Beckebaum S. ABC-transporter gene polymorphisms predict

risk for biliary complications in patients undergoing liver transplantation. J Hepatol 2014 (P896)

183. Botea F, Brasoveanu V, Ionescu MI, Iacob S, Droc G, Popescu I. Influence of hepatitis D virus co-infection

on graft survival after liver transplantation for hepatitis B virus cirrhosis. Liver Transpl 2014;20(suppl 1):S262

(P361)

184. Gheorghe L, Iacob S, Ester C, Cerban R, Pietrareanu C, Tomescu D, Droc G, Hrehoret D, Brasoveanu V,

Popescu I. Risk factors for 3 months mortality following liver transplantation in Romanian Transplant Program.

Liver Transpl 2014;20(suppl 1):S341 (P616)

185. Iacob R, Vagu C, Nastase A, Iacob S, Botea F, Grigorie R, Hrehoret D, Herlea V. Croitoru A, Dima S,

Gheorghe L, Gheorghe C, Popescu I. Expression profile of stem/progenitor cells specific genes in hepatocellular

carcinoma and potential prognostic significance. J Gastrointestin Liver Dis 2014; 23 (Suppl 1):36 (OP38)

186. Cerban R, Gheorghe L, Iacob S, Smira G, Pietrareanu C, Iacob R, Ester C, Gheorghe C. Clostridium

difficile infection, a poor outcome predictor in patients with cirrhosis. A tertiary liver transplant center perspective

from Romania. J Gastrointestin Liver Dis 2014; 23 (Suppl 1):44 (OP48)

187. Gheorghe L, Iacob R, Iacob S, Vadan R, Guinea L, Greere M, Cotruta B, Dobru D, Mihai C, Stefanescu G,

Zaharie R, Ilie M, Jinga M, Diculescu M, Gheorghe C. IBD in elderly romanian patients: epidemiological and

phenotypical charcateristics. J Gastrointestin Liver Dis 2014; 23 (Suppl 1): 107 (PP63)

188. Gheorghe L, Iacob S, Simionov I, Caruntu F, Motoc A, Arama V, Goldis A, Brisc C. A week 8 stopping

model for real life genotype 1 patients with advanced fibrosis treated with boceprevir-based triple regimen. J

Gastrointestin Liver Dis 2014; 23 (Suppl 1):7 (OP6)

189. Iacob S, Ester C, Popescu I, Gheorghe L. Risk factors for death in cirrhotic patients with non-malignant

portal vein thrombosis on the waiting list for liver transplantation. J Gastrointestin Liver Dis 2014; 23 (Suppl 1):32

(OP34)


Popescu I. Predictors of short-term post-liver transplant mortality in the Romanian Transplant Program. J

Gastrointestin Liver Dis 2014; 23 (Suppl 1):38 (OP40)

http://dx.doi.org/10.1016/S1873-9946(14)60746-7

http://dx.doi.org/10.1016/S1873-9946(14)60746-7

http://dx.doi.org/10.1016/S1873-9946(14)60740-6



191. Iacob S, Ester C, Simionov I, Gheorghe L. Liver stiffness measurement is influenced by type of

autoimmune-related liver disease. J Gastrointestin Liver Dis 2014; 23 (Suppl 1): 150 (PP113)

192. Iacob S, Greere M, Gheorghe L. Both cholestasis and portal hypertension predicted by liver stiffness, but

not by spleen stiffness. J Gastrointestin Liver Dis 2014; 23 (Suppl 1): 151 (PP114)

193. Iacob S, Cerban R, Gheorghe L. Oligofructose enriched-inulin or lactulose is better for minimal hepatic

encephalopathy in liver cirrhosis patients? J Gastrointestin Liver Dis 2014; 23 (Suppl 1): 151 (PP115)

194. Gheorghe L, Iacob S, Pietrareanu C, Hrehoret D, Brasoveanu V, Tomescu D, Droc G, Gheorghe C,

Popescu I. Improved overall mortality on the Romanian waiting list for liver transplantation. J Gastrointestin Liver

Dis 2014; 23 (Suppl 1): 152 (PP116)

195. Iacob S, Wu G, Kabar I, Huesing A, Schmidt H, Beckebaum S, Cicinnati V. Post-liver transplantation

fibrosis allograft progression is associated with increased levels of soluble NKG2D ligands. J Hepatol 2015;62

(Suppl 2): S491 (P0475)

196. Gheorghe L, Iacob S, Ester C, Iacob R, Gheorghe C, Popescu I. Safety and Efficacy of anticoagulation

therapy for portal/splanhnic vein thrombosis in patients with liver cirrhosis on the waiting list for liver

transplantation. J Hepatol 2015;62 (Suppl 2): S312 (P0055)

197. Iacob S, Ester C, Iacob R, Gheorghe C, Popescu I, Gheorghe L. Risk factors associated with overall and

bleeding-related mortality in patients with portal vein thrombosis on the waiting list for liver transplantation. J

Hepatol 2015;62 (Suppl 2): S361 (P0156)

198. Gheorghe L, Iacob S, Ester C, Iacob R, Popescu I, Gheorghe C. Safety and Efficacy of anticoagulation

therapy for splanhnic vein thrombosis in patients with liver cirrhosis on the waiting list for liver transplantation.

Gastroenterology 2015; 347 (Mo1012)

199. Iacob S, Gheorghe L, Tabacelia D, Iacob R, Gheorghe C, Popescu I. New allocation score predicting both

pre- and post-transplant survival in the Romanian National Transplant Program. Gastroenterology 2015; 359

(Mo1244)

200. Iacob S, Iacob R, Ester C, Popescu I, Gheorghe C, Gheorghe L. Risk factors associated with overall and

bleeding-related mortality in patients with portal vein thrombosis on the waiting list for liver transplantation.

Gastroenterology 2015; 359 (Mo1245)

201. Gheorghe L, Vadan R, Iacob S, Pietrareanu C, Gheorghe C. Evaluation of the nutritional status and role of

nutritional therapy in patients with liver cirrrhosis included on the waiting list for liver transplantation. J

Gastrointestin Liver Dis 2015; 24 (Suppl 1): 75 (PPIII.116)

202. Cerban R, Iacob S, Croitoru A, Dumitru R, Grasu M, Gheorghe L. Transarterial chemoembolization in

hepatocellular carcinoma – a single center experience. J Gastrointestin Liver Dis 2015; 24 (Suppl 1): 98

(PPIV.165)

203. Gheorghe L, Iacob S, Popescu I. Treatment of severe recurrent hepatitis C in liver transplant recipients

with new direct ativirals. J Gastrointestin Liver Dis 2015; 24 (Suppl 1): 105 (PPV.181)

204. Ester C, Iacob S, Lita M, Gheorghe L. Past HBV exposure among patients with non-HBV related liver

disease included on the waiting list for liver transplantation. J Gastrointestin Liver Dis 2015; 24 (Suppl 1): 105

(PPV.182)

205. Iacob S, Popescu I, Gheorghe L. Ombitasvir/paritaprevir/rionavir/dasavubir use in pre and posttransplant

setting – experience of a single large transplant center. J Gastrointestin Liver Dis 2015; 24 (Suppl 1): 105

(PPV.198)

206. Greere M, Iacob S, Coriu D, Popescu I, Gheorghe L. MELD or Child-Pugh scores – seful to predict

outcome in Budd Chiari syndrome? J Gastrointestin Liver Dis 2015; 24 (Suppl 1): 105 (PPV.200)

207. Iacob R, Vagu C, Nastase A, Ghetea L, Iacob S, Grigorie R, Botea F, Herlea V, Croitoru A, Gheorghe C,

Popescu I, Gheorghe L. Recurrence risk stratification of patients with hepatocellular carcinoma following a

potentially curative treatment using gene expression of liver stem/progenitor cells specific markers. J

Gastrointestin Liver Dis 2015; 24 (Suppl 1): 10 (OP15)

208. Iacob S, Iacob R, Vagu C, Gheorghe C, Popescu I, Gheorghe L. RS199508964 deletion in exon 6 of IRF5

gene is associated with IL28B gene SNP RS12980275 and predicts suustained virological response in patients



with recurrent hepatitis C following liver transplantation. J Gastrointestin Liver Dis 2015; 24 (Suppl 1): 11 (OP16)

209. Iacob S, Iacob R, Vagu C, Ruta S, Gheorghe C, Popescu I, Gheorghe L. RS199508964 deletion in exon 6

of IRF5 gene is corelated with IL28B gene SNP RS12980275 in patients with recurrent hepatitis C following liver

transplantation. Transplant International 2015; 28(suppl4):508, P343

210. Razvan Iacob, Codruta Vagu, Anca Nastase, Speranta Iacob, Florin Botea, Razvan Grigorie, Luminita

Stoica, Vlad Herlea, Adina Croitoru, Simona Dima, Liana Gheorghe, Cristian Gheorghe, Michael Ott and Irinel

Popescu. Significance of liver enriched transcription factors as molecular markers for hepatocellular carcinoma

recurrence after a potentially curative treatment. Transplantation 2015;99(7S):224

211. Speranta Iacob, Daniela Tabacelia, Razvan Iacob, Doina Hrehoret, Vlad Brasoveanu, Dana Tomescu,

Cristian Gheorghe, Liana Gheorghe and Irinel Popescu. New organ allocation score predicting both pre and post-

transplant survival in the Romanian National Transplant Program. Transplantation 2015;99(7S):295

212. Speranta Iacob, Miriam Maschmeier, Gang Wu, Iyad Kabar, Anna Huesing, Hartmut H.J. Schmidt, Vito

Cicinnati and Susanne Beckebaum. Once-daily extended release tacrolimus pharmacokinetics is influenced by

single nucleotide polymorphisms of CYP3A subfamily and MDR-1 in liver transplant recipients. Transplantation

2015;99(7S):150

213. Iacob S, Iacob R, Gheorghe C, Gheorghe L, Popescu I. New organ alocation score predicting both pre and

post transplant susrvival in the Romanian National Transplant Programme. Transplant International 2015;

28(suppl4):152, BO64

214. Lita M, Iacob S, Iacob R, Ester C, Cerban R, Gheorghe L. Female predominance, low rate of primary

sclerosing cholangitis-IBD phenotype, low rate of dominant strictures, cholangiocarcinoma and need for

transplantation. J Hepatol 2016;64 (Suppl 2): S637

215. Cerban R, Croitoru A, Popescu I, Iacob S, Pietrareanu C, Herlea V, Botea F, Becheanu G, Dumitru R,

Gheorghe C, Lupescu I, Gheorghe L. Management of hepatic ephitelioid hemangioendothelioma: 5 –year single

center experience. J Hepatol 2016;64 (Suppl 2): S700

216. Razvan Iacob, Codruta D. Vagu, Anca Nastase, Speranta Iacob, Florin Botea, Vlad Herlea, Adina E.

Croitoru, Simona Dima, Cristian Gheorghe, Irinel Popescu, Michael Ott and Liana Gheorghe. Hepatocyte

Reprogramming to a Progenitor-Cell Phenotype Is a Potential Mechanism of Hepatocarcinogenesis - The Role of

Reprogramming Factors: OCT4, SOX2 and NANOG. Gastroenterology 2016, Vol. 150, Issue 4, S296–S297

(Sa1367)

217. Speranta Iacob, Carmen Ester, Mihaela Lita, Liana Gheorghe. Acute Kidney Injury Severity Predicts

Mortality and Response to Terlipressin in Patients With End Stage Liver Disease Awaiting Liver Transplantation.

Gastroenterology 2016, Vol. 150, Issue 4, S1084 (Sa1644)

218. Gheorghe L, Iacob S. Prevalence of mixed cryoglobulinemia in 150 patients with chronic hepatitis C

treated with ombitasvir/paritaprevir/ritonavir+dasabuvir+ribavirin. J Gastrointestin Liver Dis 2016; 25 (Suppl 2):

37 (OP49)

219. Iacob R, Vagu C, Nastase A, Ghetea L, Iacob S, Botea F, Herlea V, Croitoru A, Dima S, Gheorghe C,

Popescu I, Ott M, Gheorghe L. Hepatocyte reprogramming in a stem-cell-like phenotype. A potential mechanism

of hepatocarcinogenesis. J Gastrointestin Liver Dis 2016; 25 (Suppl 2): 41 (OP54)

220. Iacob S, Popescu I, Gheorghe L. 100% virological response with interferon-free regimens and significant

improvement of liver stiffness in pre- and post-transplant patients with chronic C hepatitis. J Gastrointestin Liver

Dis 2016; 25 (Suppl 2): 41 (OP55)

221. Iacob S, Iacob R, Cerban R, Gheorghe C, Gheorghe L. Staging of hepatocellular carcinoma in patients

with liver cirrhosis enrolled in a screening program. J Gastrointestin Liver Dis 2016; 25 (Suppl 2): 42 (OP56)

222. Lita M, Iacob S, Ester C, Gheorghe C, Gheorghe L. Primary sclerosing cholangitis, clincal characteristics,

low incidence of the association with inflammatory bowel disease and low complication rates. J Gastrointestin

Liver Dis 2016; 25 (Suppl 2): 44 (OP58)

223. Stoica B, Becheanu G, Iacob S, Iacob R, Gheorghe C. An asymptomatic gastric Vanek’s tumor in a patient

with compensated HCV liver cirrhosis: a case presentation. J Gastrointestin Liver Dis 2016; 25 (Suppl 2): 137

(III112)



224. Cerban R, Iacob S, Croitoru A, Dumitru R, Grasu M, Ester C, Gheorghe C, Gheorghe L. Transarterial

chemoembolization in hepatocellular carcinoma – a single center experience from Romania. J Gastrointestin Liver

Dis 2016; 25 (Suppl 2): 163 (IV148)

225. Ester C, Iacob S, Lita M, Cerban R, Gheorghe L. Risk factors and impact of AKI in liver cirrhosis – the

new ICA-AKI recommendations in clinical practice. J Gastrointestin Liver Dis 2016; 25 (Suppl 2): 202 (V201)

226. Gheorghe L, Iacob MS, Popescu I. 100% virological response with 3D regimen and significant short-term

liver stiffness improvement in patients with recurrent hepatitis C following liver transplantation. Am J

Gastroenterol 2016;111 (S1):S375 (855)

227. Gheorghe L, Iacob MS, Trifan A, Stanciu C, Sirli R, Sporea I, Lupusoru R, Cijevschi C, Arama V, Brisc C,

Rogoveanu I, Iacob R, Gheorghe C. Dynamics of AFP in cirrhotic patients with virological response following 3D

therapy and severe necro-inflammation at Fibromax. Am J Gastroenterol 2016;111 (S1):S375 (856)

228. Gheorghe L, Trifan A, Iacob MS, Stanciu C, Sirli R, Sporea I, Cijevschi C, Arama V, Popescu C, Brisc C,

Goldis A, Rogoveanu I, Iacob R, Gheorghe C. 100% virological response and adherence in HCV genotype 1 liver

cirrhosis treated with 3D regimen in a Romanian real-life cohort. Am J Gastroenterol 2016;111 (S1):S392 (898)

229. Iacob S, Popescu I, Gheorghe L. 100% virological response with 3D regimen and significant short-term

liver stiffness improvement in patients with recurrent hepatitis C following liver transplantation. Hepatology

2016;64(Suppl 1):809A(1635)

230. Mihai C, Trifan A, Stanciu C, Gheorghe L, Iacob S, Diculescu M, Cijevschi C. Metabolic syndrome,

hepatic steatosis, and genotype 1b C compensated liver cirrhosis in the era of direct acting antiviral therapy.

Hepatology 2016;64(Suppl 1):949A(1918)

231. Trifan A, Singeap AM, Gheorghe L, Curescu M, Cijevschi C, Brisc C, Cojocariu C, Stefanescu G, Mihai

C, Bataga S, Miftode E, Arama V, Rogoveanu I, Sporea I, Goldis A, Suceveanu A, Iacob S, Girleanu I, Stanciu C.

The influence of clinical significant portal hypertention (stage Baveno 2) on safety, tolerability and efficacy of

paritaprevir, ritonavir, ombitasvir, dasabuvir and ribavirin (PrOD+R) in a real world large cohort of genotype 1b

HCV liver cirrhosis patients. Hepatology 2016;64(Suppl 1):950A(1920)

232. Gheorghe L, Iacob S, Iacob R, Gheorghe C. Virologcal response to

ombitasvir/paritaprevir/ritonavir+dasabuvir+ribavirin in 150 patients with mixed cryoglobulinaemia and HCV

infection. Hepatology 2016;64(Suppl 1):956A(1932)

233. Iacob S, Gheorghe L, Trifan A, Stanciu C, Sirli R, Sporea I, Lupusoru R, Cijevschi C, Arama V, Brisc C,

Rogoveanu I, Iacob R, Gheorghe C. Dynamics of AFP in cirrhotic patients with virological response following 3D

therapy and severe necro-inflammation at Fibromax. Hepatology 2016;64(Suppl 1):982A(1979)

234. Gheorghe L, Trifan A, Iacob S, Stanciu C, Sirli R, Sporea I, Cijevschi C, Arama V, Popescu C, Brisc C,

Goldis A, Rogoveanu I, Iacob R, Gheorghe C. 100% virological response and adherence in HCV genotype 1 liver

cirrhosis treated with 3D regimen in a Romanian real-life cohort. Hepatology 2016;64(Suppl 1):996A(2004)

235. Trifan A, Singeap AM, Chiriac S, Cuciureanu T, Prelipcean CC, Ciortescu I, Cojocariu C, Sfarti C, Mihai

C, Stefanescu G, Gheorghe L, Iacob S, Stanciu C. Hepatic and non-hepatic events after obtaining a SVR in

patients with genotype 1b liver cirrhosis-short time follow-up-single center experience. J Hepatol

2017;66:S127(THU-021)

236. Trifan A, Prelipcean CC, Gheorghe L, Curescu MG, Brisc C, Bataga S, Miftode E, Arama V, Chiriac SA,

Cuciureanu T, Sporea I, Goldis A, Popescu A, Iacob S, Cojocariu C, Stefanescu G, Girleanu I, Mihai C, Ciortescu

I, Stanciu C. Efficacy and safety of paritaprevir/ritonavir, ombitasvir and dasabuvir plus/minus ribavirin for

treatment of hepatitis C virus genotype 1b compensated cirrhosis in patients aged 70 years or older. J Hepatol

2017;66:S284(THU-219)

237. Trifan A, Prelipcean CC, Gheorghe L, Miftode E, Chiriac SA, Cuciureanu T, Sporea I, Goldis A, Iacob S,

Cojocariu C, Stefanescu G, Girleanu I, Mihai C, Ciortescu I, Stanciu C. Early regression of liver fibrosis evaluated

by non-invasive methods after successful antiviral therapy in patients with HCV genotype 1b compensated

cirrhosis. J Hepatol 2017;66:S285(THU-220)

238. Sporea I, Lupusoru R, Mare R, Popescu A, Sirli R, Danila M, Lazar A, Iacob S, Sandulescu L, Gheorghe

L. Dynamic oof liver stiffness values by means of transient elastography in patients with hepatitis C virus liver



cirrhosis undergoing interferon-free treatment. J Hepatol 2017;66:S245(THU-504)

239. Gheorghe L, Iacob S, Grasu M, Dumitru R, Iacob R, Lupescu I, Gheorghe C. Development of de novo

and recurrent hepatocellular carcinoma in a Romanian cohort of compensated HCV genotype 1b liver cirrhosis

with SVR after 3D and ribavirin therapy. J Hepatol 2017;66:S445(FRI-070)

240. Vadan R, Iacob S, Stoica B, Ichim S, Lita M, Manuc T, Cijevschi C, TRifan A, Dobru D, Dumitru E,

Tantau M, Brisc C, Diculescu M, GHeoorghe C, Gheorghe L. Frequency and causes of malnutrition in liver

disease patients: results from a multi-centric cross-sectional survey from gastroenterology tertiary clinics. J

Hepatol 2017;66:S571(SAT-031)

241. Iacob S, Gheorghe L, Cijevschi C, Trifan A, Stanciu C, Mihai C, Sporea I, Sirli R, Curescu M, Diculescu

M, Alexandrescu L, Sandulescu L, Goldis A, Brisc C, Simionov I, Vadan R, Pirvulescu I, Rogoveanu I,

Pietrareanu C, Seicean A, Iacob R, Gheorghe C. Predictors of persistence of clinical significant pportal

hypertension in patients with HCV liver cirrhosis following 3D therapy and SVR. J Hepatol 2017;66:S666(SAT-

479)

242. Popa RC, Mihai C, Trifan A, Stanciu C, Gheorghe L, Iacob S, Arama V, Rogoveanu I, Diculescu M,

Goldis A, Bataga S, Seicean A, Sandulescu L, Nastase R, Molagic V, Brisc C, Curescu M, Prelipcean CC. Efficacy

and safety of ambitasvir/paritaprevir/ritonavir and dasabuvir with or without RBV in hepatitis C virus genotype 1-

infected patients with compensated cirrhosis and multiple comorbidities. J Hepatol 2017;66:S732(SAT-258)

243. Ester C, Gheorghe L, Iacob S, Cijevschi C, Trifan A, Stanciu C, Sporea I, Sirli R, Curescu M, Brisc C,

Goldis A, Arama V, Caruntu F, Rogoveanu I, Seicean A, Simionov I, Vadan R, Pirvulescu I, Pietrareanu C, Iacob

R, Gheorghe C, Diculescu M. Safety, efficacy and risk of complications for cirrhotic HCV patients with

thrombocytopenia and hypoalbuminemia treated with ombitasvir/paritaprevir/ritonavir+ribavirin – a real life

cohort. UEG Journal 2017 ;5(Suppl1):A173(P0039)

244. Popescu SA, Lupusoru R, Sirli R, Danila M, Gheorghe L, Seicean A, Trifan A, Curescu M, Goldis A,

Sandulescu L, Cijevschi C, Stanciu C, Brisc C, Iacob S, Sporea I. IN how many patients we will misdiagnose

esophageal varices by using Baveno VI criteria. UEG Journal 2017 ;5(Suppl1):A629(P1335)

245. Sporea I, Lupusoru R, POpescu SA, Lazar A, Mare R, Gheorghe L, Iacob S, Sirli R. What happened with

liver stiffness values assessed by means of transient elastography in patients with HCV liver cirrhosis after DAA

treatment. UEG Journal 2017 ;5(Suppl1):A634(P1353)

246. Lita M, Ester C, Iacob S, Pietrareanu C, Cerban R, Gheorghe C, Gheorghe L. Importance of interferon-

gamma release assays in evaluating candidates for liver transplantation in a country endemic for tuberculosis.

UEG Journal 2017 ;5(Suppl1):A637(P1361)

247. Liana Gheorghe, Speranta Iacob, Cristina Cijevschi Prelipcean, Catalina Mihai, Mugur Grasu, Radu

Dumitru, Razvan Iacob, Ioana Lupescu, Pirvulescu I, Gheorghe C. Alpha fetoprotein – a useful tool for

surveillance of interferon-free treated cirrhotic patients for hepatocellular carcinoma after SVR. Gastroenterology

2017, Vol. 152, Issue 5, S298(Sat465)

248. Speranta Iacob, Liliana Gheorghe, Cristina Cijevschi Prelipcean, Anca Trifan, Carol Stanciu, Ioan Sporea,

Roxana Sirli, Manuela Curescu, Brisc C, Mihai C, Alexandrescu L, Sandulescu L, Goldis A, Arama V, Caruntu F,

Hara L, Rogoveanu I, Diculescu M, Iacob R, Gheorghe C, Seicean A, Simionov I, Vadan R, Pirvulescu I,

Pietrareanu C. Predictors of liver stiffness regression after SVR in cirrhotic patients

treated with 3D regimen. Gastroenterology 2017, Vol. 152, Issue 5, S904-905 (Tu544)

249. Ioan Sporea, Raluca Lupusoru, Roxana Sirli, Alina Popescu, Mirela Danila, Larisa D. Sandulescu,

Speranta Iacob, Ruxandra G. Mare, Liana Gheorghe. Dynamic of Liver Stiffness Values by Means of Transient

Elastography in Patients with HCV Liver Cirrhosis Undergoing Interferon Free Treatment. Gastroenterology, Vol.

152, Issue 5, S1167 (Mo 1393)

250. Gheorghe L, Iacob S, Cijevschi C, Trifan A, Stanciu C, Sporea I, Sirli R, Curescu M, Brisc C, Mihai C,

Alexandrescu L, Sandulescu L, Goldis A, Arama V, Caruntu F, Hara L, Rogoveanu I, Diculescu M, Gheorghe C,

Seicean A, Iacob R, Simionov I, Vadan R, Pirvulescu I, Pietrareanu C. Prospective analysis of discordant results

between Fibromax and Fibroscan in patients with HCV compensated liver cirrhosis before 3D antiviral

therapy initiation. Gastroenterology, Vol. 152, Issue 5, S1102 (Sa1540)



251. Anca Trifan, Cristina Cijevschi Prelipcean, Liana Gheorghe, Manuela Curescu, Ciprian Brisc, Simona

Bataga, Egidia Miftode, Victoria Arama, Rogoveanu I, Suceveanu A, Singeap AM, Chiriac S, Cuciureanu T,

Sporea I, Goldis A, Popescu A, Iacob S et al. Efficacy and Safety of Paritaprevir/Ritonavir, Ombitasvir and

Dasabuvir Plus/Minus Ribavirin for Treatment of HCV Genotype 1B Compensated Cirrhosis in Patients Aged 70

Years or Older. Gastroenterology, Vol. 152, Issue 5, S904 (Tu1541)

252. Iacob R, Popa C, Herlea V, Becheanu G, Nastase A, Ghetea L, Iacob S, Sorop A, Botea F, Badea L, Vogle

AM, Dima S, Croitoru A, Gheorghe C, Ott , Popescu I, Aloman C,Gheorghe L. The significance of Sox2

expression in hepatocellular carcinoma occurring on liver cirrhosis. Hepatology 2017; 66(Suppl1):972A(1828)

253. Speranta Iacob, Iuliana Pirvulescu, Razvan Iacob, Cristian Gheorghe, Liana Gheorghe. Evaluation with

transient elastography and controlled attenuation parameter of a cohort of patients with chronic liver diseases

admitted in a hepatology tertiary center. Hepatology 2017; 66(Suppl1):1146A(2168)

254. Iacob R, Oana A, Iacob S, Anghel D, Constantinescu A, Lupescu I, Popescu I, Gheorghe L. Phenotypic

characteristics and therapeutic multidisciplinary approach in Romanian patients diagnosed with Wilson’s disease. J

Gastrontest Liver Dis 2017; 26 (Suppl 3): 50 (PP 57)

255. Lupescu IC, Iacob S, Gheorghe L. Encephalapp Stroop Test: a modern approach for diagnosing minimal

hepatic encephalopathy. J Gastrontest Liver Dis 2017; 26 (Suppl 3): 65 (PP 92) & 123 (PD 14) (* Poster cu

distinctie)

256. Lupescu IC, Iacob S, Gheorghe L. Sudden onset of coma in liver cirrhosis: differential diagnosis and

precipitating factors. J Gastrontest Liver Dis 2017; 26 (Suppl 3): 56 (PP 72)

257. Iacob S, Pirvulescu I, Iacob R, Gheorghe C and Gheorghe L. Evaluation with transient elastography and

controlled attenuation parameter of a cohort of patients with CLD admitted in a hepatology tertiary center. J


258. Iacob S, Gheorghe L, Cijevschi C, Trifan A, Stanciu C, Sporea I, Sirli R, Curescu M, Diculescu M,

Sandulescu L, Alexandrescu L, Goldis A, Brisc C, Simionov I, Vadan R, Pirvulescu I, Rogoveanu I, Pietrareanu C,

Seicean A, Iacob R, Gheorghe C. Model to predict clinically significant portal hypertension in patients with HCV

liver cirrhosis following SVR post-therapy with Ombitasvir/Paritaprevir/ritonavir and Dasabuvir. J Gastrontest

Liver Dis 2017; 26 (Suppl 3): 86 (PP 141)

259. Greere M, Pietrareanu C, Cerban R, Lita M, Iacob S, Brasoveanu V, Popescu I, Gheorghe L. Budd Chiari

syndrome – a subacute clinical presentation in a patient with essential thrombocythemia – hematological diagnosis

revealed after liver transplant. J Gastrontest Liver Dis 2017; 26 (Suppl 3): 91 (PP 152)

260. Sporea I, Lupusoru R, Mare R, Popescu A, Gheorghe L, Iacob S, Sirli R. Dynamic of liver stiffness values

by means of transient elastography in patients with HCV liver cirrhosis undergoing interferon-free treatment. J


261. Popescu A, Lupusoru R, Sirli R, Danila M, Gheorghe L, Seicean A, Trifan A, Curescu M, Goldis A,

Sandulescu L, Cijevschi C, Stanciu C, Brisc C, Iacob S, Sporea I. In how many patients will we misdiagnose

esophageal varices by using the Baveno VI criteria? J Gastrontest Liver Dis 2017; 26 (Suppl 3): 121 (PD 9) (*

Poster cu distinctie)

262. Lita M, Iacob S, Iacob R, Ester C, Pietrareanu C, Cerban R, Gheorghe C, Gheorghe L. Medium-term

prognosis in patients with primary biliary cholangitis – experience of a tertiary hepatology center. J Gastrointestin

Liver Dis 2017; 26 (Suppl 3): 128 (PD 25) (* Poster cu distinctie)

263. Pietrareanu C, Jorza C, Iacob S, Gheorghe L. Screening instruments to detect alcohol consumption in

cirrhotic patients included on the waiting list for liver transplantation. J Gastrointestin Liver Dis 2017; 26 (Suppl

3): 132 (PD 34) (* Poster cu distinctie)


by means of Transient Elastography in patients with HCV liver cirrhosis undergoing interferon-free treatment. J

Gastrointestin Liver Dis 2017; 26 (Suppl 3): 133 (PD 36) (* Poster cu distinctie)

265. Cerban R, Iacob S, Paslaru L, Dumitru R, Grasu M, Ester C, Lita M, Pietrareanu C, Constantin G,

Gheorghe C and Gheorghe L. Utility of measurementof alpha-fetoprotein and des-ϒ-carboxy prothrombin for

diagnosis of hepatocellular carcinoma in patients admitted in a large transplant center in Romania. J Gastrointestin



Liver Dis 2017; 26 (Suppl 3): 135 (PD 39) (* Poster cu distinctie)

266. Iacob S, Badelita S, Lita M, Iacob R, Gheorghe C, Gheorghe L, Coriu D, Jercan A. Diagnosis and

Evaluation of Liver Amyloidosis by Transient Elastography. Gastroenterology 2018;154(Suppl 1):S729

267. Iacob S, Lita M, Tomescu D, Droc G, Pietrareanu C, Hrehoret D, Brasoveanu V, Iacob R, Gheorghe C,

Popescu I, Gheorghe L. Pre and Post-transplant outcomes after an episode of acute on chronic liver failure.

Gastroenterology 2018;154(Suppl 1):S1143

268. Lupescu IC, Iacob S, Gheorghe L. Assessment of subclinical hepatic encephalopathy by using

EncephalApp Stroop test and brain MRI. J Hepatol 2018; 68 (Suppl 1):S746

269. Iacob R, Iacob S, Oana A, Cristina AD, Constantinescu A, Lupescu IG, Popescu I, Gheorghe L. J Hepatol

2018; 68 (Suppl 1):S653-654

270. Iacob S, Cicinnati V, Maschmeier M, Scmidt H, Beckebaum S. Follow-up of non-HLA and anti-HLA

antibodies: importance in graft failure after liver transplantation. J Hepatol 2018; 68 (Suppl 1):S385

271. Iacob S, Ester C, Cerban R, Pietrareanu C, Iacob R, Gheorghe C, Gheorghe L. Factori predicivi pentru

regresia cirozei hepatice la un an dupa eradicarea VHC. J Gastrointestin Liver Dis 2018; 27 (Suppl 2):36 (Lucrare

premiata)

272. Cerban R, Ester C, Iacob S, Paslaru L, Dumitru R, Grasu M, Constantin G, Gheorghe C, Gheorghe L.

Factori predictivi pt raspunsul complet si recurenta la pacientii cu carcinom hepatocelular tratati prin

chemoembolizare transarteriala. J Gastrointestin Liver Dis 2018; 27 (Suppl 2):33

273. Lupescu IC, Iacob S, Pietrareanu C, Lupescu IG, Gheorghe L. Cat de frecvent intalnita este afectarea

neurologica la pacientii aflati pe lista de asteptare pentru transplant hepatic? J Gastrointestin Liver Dis 2018; 27

(Suppl 2):58

274. Ester C, Cerban R, Iacob S, Pietrareanu C, Lita M, Ichim S, Constantin G, Paslaru L, Ruta S, Gheorghe L.

Detectarea precoce a NAFLD si a complicatiilor sale la pacientii transplantati hepatic prin utilizarea biomarkerilor.

J Gastrointestin Liver Dis 2018; 27 (Suppl 2):51

275. Gheorghe L, Iacob S, Mihai C, Girleanu I, Ciortescu I, Sandulescu L, Preda C, Diculescu M, Cijevschi C,

Bataga S, Drug V, Plesa A, Cojocariu C, Stefanescu G, Singeap AM, Pietrareanu C, Simionov I, Vadan R,

Pirvulescu I, Iacob R, Gheorghe C, Sirli R, Sporea I, Mitrut P, Stanciu C, Trifan A. Beneficiile tratamentului cu

sofosbuvir/ledipasvir intr-o cohort de paccienti cu ciroza hepatica decompensate secundar VHC genotip I din

practica curenta. J Gastrointestin Liver Dis 2018; 27 (Suppl 2):52

276. Gheorghe L, Iacob S, Mihai C, Cijevschi C, Preda C, Pietrareanu C, Vadan R, Simionov I, Pirvulescu I,

Iacob R, Diculescu M, Gheorghe C. Antiviralele cu actiune directa nu cresc rata HCC de novo sau riscul recurentei

HCC dupa tratamente loco-regionale. J Gastrointestin Liver Dis 2018; 27 (Suppl 2):52

277. Iacob S, Badelita S, LIta M, Iacob R, Gheorghe L, Gheorghe C, Coriu D, Jercan A. Elastografia tranzitorie

– o metado neinvaziva folosita pentru diagnosticul amiloidozei hepatice. J Gastrointestin Liver Dis 2018; 27

(Suppl 2):56

278. Lupescu IC, Iacob S, Anghel D, Iacob R, Dulamea AO, Marian M, Lupescu IG, Gheorghe L. Evaluarea

afectarii neurologice intr-o cohorta de pacienti cu boala Wilson. J Gastrointestin Liver Dis 2018; 27 (Suppl 2):58

279. Iacob R, Alexe MG, Iacob S, Cerban R, Hrehoret D, Brasoveanu V, Grasu M, Dumitru R, Croitoru A,

Becheanu G, Herlea V, Lupescu I, Diculescu M, Gheorghe C, POpescu I, Gheorghe L. Rezultatul terapiei

multimodale la pacientii diagnosticati cu hepatocracinom intr-un centru tertiar de gastroenterologie. J

Gastrointestin Liver Dis 2018; 27 (Suppl 2):56

280. Iacob R, Alexe MG, Iacob S, Cerban R, Grasu M, Dumitru R, Toma M, Lupescu I, Croitoru A, Becheanu

G, Dumbrava M, Diculescu M, Gheorghe L, Gheorghe C. Particularitatile clinice ale carcinomului hepatocellular

la pacienii referiti unui centru tertiar de gastroenterologie din Romania si eficienta procedurii de screening. J


281. Tudoroiu MI, Constantin G, Pislaru L, Iacob S, Tomescu D, Gheorghe C, Popescu I, Gheorghe L. Rolul

gelatinazei neutrofilice associate lipocalinei (NGAL) in diagnosticul insuficientei renale acute precoce

posttransplant hepatic. J Gastrointestin Liver Dis 2018; 27 (Suppl 2):91

282. Speranta Iacob, Mihaela Lita, Dana Tomescu, Gabriela Droc, Corina Pietrareanu, Doina Hrehoret, Vlad



Brasoveanu, Razvan Iacob, Cristian Gheorghe, Irinel Popescu, Liana Gheorghe. Predictive Factors for Death on a

Long Waiting List for Liver Transplantation after an Episode of Acute on Chronic Liver Failure. Transplantation

2018; 102:S124

283. Iacob S, Cicinnati V, Maschmeier M, Schmidt H, Beckebaum S. C4d Deposition -

An independent Predictor of Graft Failure Following Liver Transplantation. Transplantation 2018; 102:S621

284. S.Iacob, R. Iacob, C. Pietrareanu, C. Ester, R. Cerban, C. Gheorghe and L. Gheorghe. What variables can

predict long term one stage fibrosis regression in HCV infected patients after SVR? Hepatology 2018

285. Carmen Ester, Razvan Cerban, Speranta Iacob, Razvan Iacob, Georgiana Constantin, Liliana

Pislaru, Sorop Andrei, Mihaela Ghioca, Lorand Savu, Irinel Popescu, Liana Gheorghe. Recipient PNPLA3

and TM6SF2 genotypes and risk of NAFLD folllowing liver transplantation. J Hepatol 2019;Suppl1S, 70:

538 (FRI293)

286. Speranta Iacob, Catalina Stanescu, Razvan Iacob, Roxana Vadan, Cristian Gheorghe, Ioana

Lupescu, Liana Gheorghe. Right psoas muscle area: Prognostic factor in patients with cirrhosis Child Pugh

class C included on the waiting list for liver transplantation. J Hepatol 2019;Suppl1S, 70: 664 (SAT-052)

287. Speranta Iacob, Razvan Iacob, Cristian Gheorghe, Liana Gheorghe. SHEAR WAVE

ELASTOGRAPHY USE FOR SCREENING OF CLINICALLY SIGNIFICANT PORTAL

HYPERTENSION AFTER HCV CURE. Gastroenterology 2019; Suppl 1:156(6):S1052

288. Stoica Bianca, Razvan Iacob, Speranta Iacob, Adina Croitoru, Cristina Radu, Cristian Gheorghe. Real life

results of first line palliative chemotherapy in pancreatic ductal adenocarcinoma. J Gastrointestin Liver Dis 2019;

28 (Suppl 2):13

289. Ester Carmen, Razvan Cerban, Razvan Iacob, Speranta Iacob, Andrei Sorop, Lorand Savu, Mihaela

Ghioca, Georgiana Constantin, Liliana Pislaru, Simona Ruta, Irinel Popescu, Liana Gheorghe. Predictors for

metabolic syndrome and cardiovascular risk in liver transplant recipients – a single center experience. J


290. S. Iacob, M. Onica, C. Pietrareanu, C. Ester, R. Cerban, R. Iacob, C. Gheorghe, I. Popescu, L. Gheorghe.

Metabolic and renal function evaluation after HCV cure in LT recipients. J Gastrointestin Liver Dis 2019; 28

(Suppl 2):18

291. Greere Madalina, Speranta Iacob, Carmen Ester, Liana Gheorghe. Risk factors and outcome for portal

vein thrombosis in patients with cirrhosis. J Gastrointestin Liver Dis 2019; 28 (Suppl 2):77

292. Speranta Iacob, Razvan Iacob, Cristian Gheorghe, Liana Gheorghe. Shear wave and transient

elastography use in the follow-up of hepatitis C patients with SVR. J Gastrointestin Liver Dis 2019; 28 (Suppl

2):153

IX.Conferinte invitate la manifestari stiintifice Internationale si Nationale.

1. L. Gheorghe, S. Iacob. Referral for liver transplantation: MELD and beyond. 17th World Congress of the

International Association of Surgeons, Gastroenterologists and Oncologists, 5-8 September 2007, Bucharest,

Romania

2. Iacob S. Real time elastography – a noninvasive tool for evaluation of recurrent hepatitis C following liver

transplantation.TTS nKOL Meeting, St Petersburg, 28-30 June 2008

3. S. Iacob. Effect of MDR1 and ABCG8 polymorphisms on hepatitis C recurrence after liver

transplantation. IASGO CME Postgraduate course. Liver Transplantation – An Interdisciplinary Approach. 27-30

September 2010, Essen, Germany

4. Iacob Speranta. NPP experience in Romania. NPP Regional Experts’ Meeting, 21-22 November 2013,

Skopje, Macedonia

5. Iacob S. Prophylaxis of HBV reinfection of the graft. Up-to-Date in Hepatology Course, 25-26 April 2014,

Bucharest, Romania (EASL endorsed)

6. Speranta Iacob. Therapy of hepatitis C: future prospects. Up-to-Date on Hepatology Course, 27-28 April

2015, Bucharest, Romania



7. Iacob S. Curing HCV infection – case presentations. UpDate on Hepatology Course, 27-28 May 2015,

Bucharest, Romania

8. Iacob S. Vascular liver diseases (Portal vein thrombosis and Budd Chiari syndrome) – case presentation.

UpDate on Hepatology Course, 27-28 May 2015, Bucharest, Romania

9. L. Gheorghe, S. Iacob. Combined therapy of Peginterferon alpha-2a and Ribavirin versus Interferon alpha-

2a and Ribavirin in chronic hepatitis C – side effects and tolerability. 9-th Romanian Congress of Gastroenterology,

Hepatology and Gastrointestinal Endoscopy, Craiova, 24-27th September 2003

10. S. Iacob. Predictive factors associated with recurrent chronic hepatitis C. Round Table: Liver

Transplantation and HCV infection. XXVII-th National Symposium of Gastroenterology, Hepatology and

Digestive Endoscopy, Poiana Brasov, 14-17th June 2006

11. L. Gheorghe, S. Iacob. Mortality on waiting list for liver transplantation. The Second National Symposium

of the Romanian Hepato-bilio-pancreatic Surgery and Liver Transplantation, Bucharest, 18-21 April 2007

12. S. Iacob. Wilson disease and pregnancy. Round Table: Pregnancy and gastrointestinal diseases. XXVIII-th

National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Sibiu, 14-16th June 2007

13. Speranta Iacob, Liana Gheorghe, Irinel Popescu. Influenta regimurilor imunosupresoare asupra

supravietuirii si recurentei VHC post-transplant hepatic. Al IV-lea Simpozion “Acad Nicolae Cajal”, 26-28 Martie

2008, Bucuresti

14. Iacob S. Care este locul transplantului hepatic in boala Wilson? In cadrul mesei rotunde: Boli metabolice

hepatice de la stadiul presimptomatic la transplantul hepatic. Xth National Congress of Gastroenterology,

Hepatology and Digestive Endoscopy, Iasi 19-21 June 2008

15. Iacob S. Profilul autoanticorpilor serici si autoantigene la pacientii cu sindrom de overlap autoimun. In

cadrul mesei rotunde: Sindromul de overlap autoimun in patologia hepatica: stim mai mult azi decat ieri? The

XXIXth National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Cluj-Napoca 18-20

June 2009

16. Iacob S. Transplantul hepatic pentru pacientul cu ciroza virala. The XXXIth National Symposium of

Gastroenterology, Hepatology and Digestive Endoscopy, Mamaia, Romania, 19-21 May 2011

17. Iacob S. HEPATITA B – Simplificarea conceptului terapeutic intr-o boala complexa. The XXXIVth

National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Oradea, Romania, 11-14 June

2014

18. Iacob S. Conferinta “Tanar Cercetator”: Transplantul hepatic. The XXXIVth National Symposium of

Gastroenterology, Hepatology and Digestive Endoscopy, Oradea, Romania, 11-14 June 2014

19. Iacob S. The indications of the liver transplantation and the pre-transplantation management. Congresul

Universitatii de Medicina si Farmacie Carol Davila Bucuresti, 28-30 May 2015

20. Iacob S. Mai exista pacienti “DIFICIL DE TRATAT” cu regimuri fara interferon? In cadrul Mesei

Rotunde “En Vogue” in tratamentul hepatitei C. The XXXVth National Congress of Gastroenterology, Hepatology

and Digestive Endoscopy, Iasi, Romania, 11-13 June 2015

21. Iacob S. Screening-ul in carcinomul hepatocelular. In cadrul Mesei Rotunde “Screening-ul in

Gastroenterologie – dincolo de ghidurile actuale. The XXXVth National Congress of Gastroenterology,

Hepatology and Digestive Endoscopy, Iasi, Romania, 11-13 June 2015

22. Iacob S. Prescriptia. In cadrul Mesei Rotunde “ Care este cea mai adecvata combinatie de antivirale directe

pentru pacientul roman cu HCV?” The XXXVth National Congress of Gastroenterology, Hepatology and

Digestive Endoscopy, Iasi, Romania, 11-13 June 2015

23. Iacob S, Simionov I. Managementul RA & DILI (interacțiunilor medicamentoase) – in cadrul Mesei

Rotunde “HEPATITA CRONICĂ HCV/ O ABORDARE CRITICĂ A TERAPIEI ANTIVIRALE ÎN HEPATITA

C ÎN 2016”. The XXXVIth National Congress of Gastroenterology, Hepatology and Digestive Endoscopy, Cluj-

Napoca, Romania, 8-11 June 2016

24. Iacob S. CMV reactivation in IBD – diagnostic and therapeutic challenges. 8th National Symposium on

Inflammatory Bowel Diseases, 29th of September – 1st of October 2016, Bucharest, Romania

25. Speranta Iacob, Liana Gheorghe. Managementul bolii cronice hepatice si impactul asupra riscului CHC.



Atelierul “Ridicand stacheta in carcinomul hepatocelular”. Al treilea congres national de oncologie medicala si

radioterapie al federatiei societatilor romane de cancer, 3-5 noiembrie 2016, Bucuresti, Romania

26. Speranta Iacob. HCV therapy of GT-1 patients now and in the future. Strategies for simplification. 4th

UpDate on Hepatology Course Bucharest 6-7 April 2017, Romania

27. Speranta Iacob. Treatment of LT HCV positive recipients. HOPE for CURE VERNISSAGE. 15-16

Septembrie 2017, Budapesta, Ungaria

28. Speranta Iacob. Benefits of DAA therapy in HCC patients. HOPE for CURE VERNISSAGE. 15-16

Septembrie 2017, Budapesta, Ungaria

29. Gheorghe L, Iacob S, Cerban R, Iacob R, Pislaru L. Noutati in carcinomul hepatocelular la pacientii cu

ciroza/fibroza avansata – punctul de vedere al gastroenterologului. Congresul National de Radiologie si Imagistica

Medicala, 6-8 Octombrie 2017, Bucuresti, Romania

30. Iacob S. Treatment update for delta hepatitis. Al 37-lea Congres de Gastroenterologie, Hepatologie și

Endoscopie Digestivă, Bucuresti 22-24 iunie 2017

31. Iacob S. Impact of antiviral therapy on the long term outcome of HCV liver disease. Al 37-lea Congres de

Gastroenterologie, Hepatologie și Endoscopie Digestivă, Bucuresti 22-24 iunie 2017

32. Iacob S. How to improve the long term outcome after liver transplantation? 5th UpDate on Hepatology

Course, „Best Practices in Clinical Hepatology”, Bucharest 26th-27th April 2018

33. Iacob S. HCV patients populations with challenging treatment decision – Liver transplantation patients. 5th

UpDate on Hepatology Course, „Best Practices in Clinical Hepatology”, Bucharest 26th-27th April 2018

34. Iacob S. Progrese in managemetul hepatitei autoimmune. Curs Hepatologie “Breaking news in

Hepatology”. Al 38-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, 24-26 Mai

2018, Craiova, Romania

35. Iacob S. Hepatita E: o cauza de boala hepatica trecuta cu vederea. In cadrul Mesei Rotunde “Provocari in

hepatitele virale”. Al 38-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, 24-26

Mai 2018, Craiova, Romania

36. Iacob S. Urmarirea pacientului dupa transplantul hepatic pentru depistarea recurentelor afectiunilor

maligne si non-maligne. In cadrul Mesei Rotunde “Transplantul Hepatic pentru gastroenterologul practician”. Al

38-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, 24-26 Mai 2018, Craiova,

Romania

37. Iacob S. Hepatita Delta – o boală neglijată? In cadrul Mesei Rotunde: “NOU ȘI VECHI ÎN HEPATITELE

VIRALE CRONICE”. CONGRESUL UNIVERSITĂȚII DE MEDICINĂ ȘI FARMACIE CAROL DAVILA –

Editia a 6a, 7-9 iunie 2018, BUCUREȘTI, Romania

38. Iacob S. Depistare precoce. Simpozion-Masă rotundă: Tratamentul multimodal al hepatocarcinomului.

National Congress of the Romanian Association of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation,

12th edition. 19-21 September 2018, Cluj, Romania

39. Irinel Popescu, Vladislav Brasoveanu, Doina Hrehoret, Bogdan Dorobantu, Emil Matei, Florin Botea,

Mihai Grigorie, Mihail Pautov, Dana Tomescu, Gabriela Droc, Daniela Ungureanu, Ruxandra Fota, Gratiela

Manga, Mihai Popescu, Liana Gheorghe, Speranta Iacob, Corina Pietrareanu, Mariana Mihaila, Sanda

Constantinescu, Cristian Gheorghe, Ioana Lupescu, Mugur Grasu, Mirela Boroș, Radu Dumitru, Mihai Toma,

Liliana Paslaru, Laura Vlad, Ileana Constantinescu, Ileana Dima, Vlad Herlea, Gabriel Becheanu, Catalin

Pecheanu, Daniela Sasalovici. Transplantul de ficat cu donator viu. In cadrul Sesiunii I: Transplantul hepatic.

National Congress of the Romanian Association of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation,

12th edition. 19-21 September 2018, Cluj, Romania

40. Coriu D, Ene A, Codita I, Badelita S, Jercan A, Iacob S, Stoica E, Jurcut R, Draghici M, Dragomir M,

Jardan D, Dobrea C. Transthyretin-related hereditary amyloidosis – a long journey to diagnosis. ATTR

Amyloidosis Academy, Bucharest, 20-21 September 2018

41. Speranta Iacob. Cholestatic pregnancy-related liver disease. 6th UpDate on Hepatology Course, „From

theory to practice in Liver Disease”, Bucharest 5th-6th April 2019

42. Speranta Iacob. Optimizing HCV treatment across all disease stages. 6th UpDate on Hepatology Course,



„From theory to practice in Liver Disease”, Bucharest 5th-6th April 2019

43. Speranta Iacob. US technology (SSI-SWE, Aixplorer) during Hands-on workshop: Fibrosis assessment.

6th UpDate on Hepatology Course, „From theory to practice in Liver Disease”, Bucharest 5th-6th April 2019

44. Speranta Iacob. Diagnosticul non-invaziv al NAFLD/NASH. Corelatii anatomopatologice si clinice in

gastroenterologie, Curs-editia I, Athenee Palace Hilton – Bucuresti, 19-20 Aprilie 2019

45. Speranta Iacob. Common mistakes in inherited liver disorders and how to avoid them. In cadrul mesei

rotunde “Common mistakes in hepatology”. Al 39-lea Congres National de Gastroenterologie, Hepatologie si

Oncologie Digestiva, 6-8 Iunie 2019, Timisoara, Romania

46. Speranta Iacob. Pro Liver transplant beyond Milan. In cadrul “Controversy 1. Liver transplant beyond

Milan criteria”. Al 39-lea Congres National de Gastroenterologie, Hepatologie si Oncologie Digestiva, 6-8

Iunie 2019, Timisoara, Romania

47. Speranta Iacob. Hepatitis C after the cure: achievements and controversies sau HCV – What have we

learned after SVR? Al 39-lea Congres National de Gastroenterologie, Hepatologie si Oncologie Digestiva, 6-

8 Iunie 2019, Timisoara, Romania

48. Speranta Iacob. Intrahepatic cholestasis: current and emerging concepts. 7th Transylvanian Meeting for

Liver Interventions, 21 Septembrie, Cluj, Romania

X.Alte lucrari si contributii Stiintifice.

A.Prezentari orale la manifestari stiintifice internationale:

1. S. Iacob, L. Gheorghe, R. Iacob, C. Gheorghe, D. Bucur, A. Croitoru, I. Popescu. Predictive factors for the

development of hepatocellular carcinoma in cirrhotic patients. 14th World Congress of the International

Association of Surgeons and Gastroenterologists (IASG), Zurich, Switzerland, 9-12 September 2004

2. R. Iacob, J. Quinton, F. Guillemot, F. Pattou, I. Bancila, C. Gheorghe, S. Iacob, L. Gheorghe, M.

Diculescu. Esophageal manometry abnormalities after gastric banding for morbid obesity. 13th United European

Gastroenterology Week (UEGW), Copenhagen, Denmark, 15-19 October 2005

3. I. Popescu, D. Tulbure, L. Gheorghe, D. Hrehoret, L. Popa, S. Iacob, M. Malago. ABO incompatible liver

transplantation: a case report. Session: “Liver transplantation and Liver Surgery”. 8-th Symposium and

Postgraduate Course of the International Association of Surgeons and Gastroenterologists (IASG), 5-7 April 2006

4. S. Iacob, S. Beckebaum, V. Cicinnati, R. Iacob, C. Klein, L. Gheorghe, C. Gheorghe, I. Popescu, A.

Frilling, M. Malago, G. Gerken, C. Broelsch. Protective factors for severe recurrence of hepatitis C after liver

transplantation. Digestive Disease Week, Los Angeles, USA, 20-25 May 2006

5. R. Iacob, I. Vartan, L. Gheorghe, B. Cotruta, S. Iacob, L. Tugui, I. Bancila, M. Ionescu, I. Popescu, C.

Gheorghe. Familial polyposis syndromes registry – screening, diagnosis, tratment and follow-up. 17th World

Congress of the International Association of Surgeons, Gastroenterologists and Oncologists, 5-8 September 2007,

Bucharest, Romania

6. Gheorghe L, Iacob S, Iacob R, Becheanu G, Dumbrava M. Real – time elastography – a novel approach to

assess liver fibrosis in patients with chronic hepatitis C. 18th World Congress of the International Association of

Surgeons, gastroenterologists and Oncologists, 8-11 October 2008, Istanbul, Turkey

7. Shen Q, Beckebaum S, Iacob S, Weber F, Sotiropoulos GC, Radtke A, Paul A, Gerken G, Cicinnati VR.

Decreased expression of miR-199a-5p contributes to increased cell invasion by functional deregulation of DDR1

activity in hepatocellular carcinoma. 19th World Congress of the International Association of Surgeons,

Gastroenterologists and Oncologists (IASGO), 23-26 September 2009, Beijing, China



diseases. Deutsche Transplantationsgesellschaft 18. Jahrestagung, 29-31 Oktober 2009, Berlin, Germany




cassette transporter gene polymorphisms and insulin resistance as risk factors for advanced fibrosis following liver

transplantation for HCV infection. Digestive Disease Week, 1-5 May 2010, New Orleans, USA (OP487)

10. S.M. Iacob, V.R. Cicinnati, A. Dechene, C.G. Klein, M. Lindemann, G.C. Sotiropoulos, A. Radtke, I.

Popescu, G. Gerken, A. Paul, S. Beckebaum. Effect of MDR1 and ABCG8 polymorphisms on hepatitis C

recurrence following liver transplantation. The XXIII International Congress of The Transplantation Society, 15-19

August 2010, Vancouver, Canada (O19.09)

11. S. Beckebaum, S.M. Iacob, C.G. Klein, A. Dechene, J. Varghese, H.A. Baba, G.C. Sotiropoulos, A.

Radtke, G. Gerken, A. Paul, V.R. Cicinnati. Transient elastography and development of a non-invasive

multiparameter score for assessment of allograft fibrosis in liver transplant patients. The XXIII International

Congress of The Transplantation Society, 15-19 August 2010, Vancouver, Canada (O48.08)

12. Gheorghe L, Pascu O, Ceausu E, Csiki IE, Iacob S, Caruntu F, Simionov I, Vadan R. Access to combined

antiviral therapy for hepatitis C in Romania. 18th UEGW, Barcelona Spain, 24-26 October 2010 (OP201)

13. Smira G, Gheorghe C, Gheorghe L, Iacob S, Iacob R. Chronic administration of rifaximin for the

maintenance of remission of hepatic encephalopathy. 18th UEGW, Barcelona Spain, 24-26 October 2010 (OP253)


fractalkine receptor and risk for anastomosis stenosis after liver transplantation. 15th Congress of the European

Society for Organ Transplantation 22nd Annual BSHI Conference, 4-7 September 2011, Glasgow, United

Kingdom (O-042)

15. Iacob S, Cicinnati V, Wu G, Dechene A, Popescu I, Paul A, Gerken G Beckebaum S. ABCG5/8 and

ABCB1 polymorphisms as risk factors for advanced fibrosis following liver transplantation. 15th Congress of the

European Society for Organ Transplantation 22nd Annual BSHI Conference, 4-7 September 2011, Glasgow,

United Kingdom (O-107)

16. Iacob S, Cicinnati V, Dechene A, Popescu I, Paul A, Gerken G Beckebaum S.Altered cytokines pattern in

patients with ischemic type biliary lesions following liver transplantation. 15th Congress of the European Society

for Organ Transplantation 22nd Annual BSHI Conference, 4-7 September 2011, Glasgow, United Kingdom

(RO-105)

17. Iacob S, Cicinnati VR, Wu G, Lindemann M, Heinemann FM, Rebmann V, Horn PA, Kabar I, Schmidt

HH, Beckebaum S. Soluble ligands for activating natural killer receptor (NKG2D) are biomarkers for progression

of hepatic fibrosis after liver transplantation. 24th International Congress of the Transplantation Society, 15-19 July

2012, Berlin, Germany

18. Iacob S, Cicinnati VR, Wu G, Xu L, Kabar I, Schmidt HH, Beckebaum S. Role of ATP-Binding cassette

transporter gene polymorphisms and metabolic risk factors for allograft fibrosis after liver transplantation. 24th

International Congress of the Transplantation Society, 15-19 July 2012, Berlin, Germany

19. S. Iacob, L. Cvas, M. Greere, R. Vadan, I. Simionov, C. Pietrareanu and L. Gheorghe. Real time and

transient elastography in chronic hepatitis B and C: which one is better? The Liver Meeting®’s Clinical Research

Workshop, 9-13 November 2012, Boston, MA, USA

20. Iacob S, Cicinnati VR, Lindemann M, Heinemann FM, Rebmann V, Kabar I, Schmidt HJ, Radtke A,

Beckbaum S. Soluble ligands for activating natural killer receptor (NKG2D) as screening tool to predict severity

of allograft fibrosis after liver transplantation. 48th annual meeting of the European Association for the Study of the

Liver, 24-28 April 2013, Amsterdam, The Netherlands

21. Iacob S, Beckebaum S, Lindemann M, Heinemann F, Rebmann V, Wu G, Kabar I, Radtke A, Baba H,

Cicinnati V. Donor specific anti-MHC class II antibodies – risk factors for liver graft failure. 23rd World Congress

of the International Association of Surgeons, Gastroenterologists and Oncologists, 18-21 September 2013,

Bucharest, Romania

22. Iacob S, Cicinnati V, Lindemann M, Heinemann F, Rebmann V, Kabar I, Schmidt H, Radtke A,

Beckebaum S. Soluble Ligands for activating natural killer receptor (NKG2D) – indicators for severe fibrosis in

liver transplant recipients. 23rd World Congress of the International Association of Surgeons, Gastroenterologists

and Oncologists, 18-21 September 2013, Bucharest, Romania

23. S. Iacob, R. Iacob, C. Gheorghe, L. Gheorghe, I. Popescu. New organ allocation score predicting both pre



and post-transplant survival in the Romanian National Transplant Program. ESOT- 17th Congress of the European

Society for Organ Transplantation, Bruxelles, Belgia, 13-16 September 2015

24. Speranta Iacob, Miriam Maschmeier, Anna Hüsing, Iyad Kabar, Hartmut Schmidt, Vito Cicinnati,

Susanne Beckebaum. INFLUENCE OF DONOR AND RECIPIENT CYP3A5 AND ABCB1 GENETIC

POLYMORPHISMS ON TACROLIMUS DOSAGE AND TROUGH LEVEL. ESOT- 18th Congress of the

European Society for Organ Transplantation, Barcelona, Spania, 24-27 September 2017

25. Speranta Iacob, Irinel Popescu, Liana Gheorghe. PREDICTORS OF POST-TRANSPLANT SEVERE

STEATOSIS IDENTIFIED BY FIBROSCAN WITH CONTROLLED ATTENUATION PARAMETER. ESOT-

18th Congress of the European Society for Organ Transplantation, Barcelona, Spania, 24-27 September 2017

26. Speranta Iacob, Mihaela Lita, Dana Tomescu, Gabriela Droc, Corina Pietrareanu, Doina Hrehoret, Vlad

Brasoveanu, Razvan Iacob, Cristian Gheorghe, Irinel Popescu, Liana Gheorghe. Predictive Factors for Death on a

Long Waiting List for Liver Transplantation after an Episode of Acute on Chronic Liver Failure. TTS – 27th

International Congress of the Transplantation Society, Madrid, Spain, 30 June – 5 July 2018

27. S. Iacob, M. Onica, C. Pietrareanu, C. Ester, R. Cerban, R. Iacob, C. Gheorghe, I. Popescu, L. Gheorghe.

LACK OF METABOLIC PROFILE AND RENAL FUNCTION IMPROVEMENT AFTER HCV

ERADICATION - ANALYSIS AT 24MONTHS AFTER INTERFERON-FREE TREATMENT IN LT

RECIPIENTS. 19th Congress of the European Society for Organ Transplantation, Copenhagen, Danemarca, 15-18

September 2019

28. Speranta Iacob, Catalina Stanescu, Razvan Iacob, Roxana Vadan, Cristian Gheorghe, Ioana Lupescu,

Irinel Popescu, Liana Gheorghe. RIGHT PSOAS MUSCLE AREA EVALUATION IN CIRRHOTICS --

PREDICTOR OF BOTH PRE AND POST-LIVER TRANSPLANT DEATH. 19th Congress of the European

Society for Organ Transplantation, Copenhagen, Danemarca, 15-18 September 2019

29. Iacob S, Hrehoret D, Stoica L, Apavaloaie C, Droc G, Tomescu D, Brasoveanu V, Vlad L, Pietrareanu C,

Razvan Iacob, Gheorghe C, Gheorghe L, Popescu I. Risk factors for bacterial infections following the first month

after liver transplantation and the impact on survival. 19th Congress of the European Society for Organ

Transplantation, Copenhagen, Danemarca, 15-18 September 2019

B.Prezentari orale la manifestari stiintifice nationale:

1. Diculescu M., Iacob R., Iacob S. – Therapeutical solutions for patients with chronic hepatitis C

nonresponders to standard interferon. Scientific Meeting of Fundeni Clinical Institute, 6-8 December, 2001

2. Gheorghe L., Iacob R., Gheorghe C., Vădan R., Toader C., Iacob S., Simionov I. – Simultaneous

administration of human albumine and terlipressine vs. Plasma expanders and terlipressine in the treatment of type

I hepatorenal syndrome for patients on the waiting list for liver transplantation. Scientific Meeting of Fundeni

Clinical Institute, 5-7 December 2002

3. Arbănaş T., Gheorghe L., Croitoru A., Iacob R., Iacob S., Atanasiu C., Ciocirlan M., Diculescu M. –

Gastrointestinal carcinoid tumors : 10 years of experience in Gastroenterology and Hepatology Center. Scientific

Meeting of Fundeni Clinical Institute, 5-7 December 2002

4. Gheorghe L., Simionov I., Iacob R., Vădan R., Iacob S., Pârvulescu I. – Overlap syndrome between

autoimmune hepatitis and cholestatic liver diseases : frequency and predictive factors. Scientific Meeting of

Fundeni Clinical Institute, 5-7 December 2002

5. L. Gheorghe, R. Iacob, S. Iacob, C. Gheorghe. I. Bancila, I. Parvulescu. Valoarea scorului MELD vs

caracteristici tumorale in predictia mortalitatii la pacientii cu ciroza hepatica si carcinom hepatocelular. Scientific

Meeting of Fundeni Clinical Institute, 11 December 2003

6. Gheorghe C., Iacob S., Iacob R., Gheorghe L., Diculescu M. – Ligation versus endoscopic sclerotherapy :

efficacy, complications, reccurence rate. 13th National Congress of Hepatology, Bucharest, 26-27 June 2003

7. Iacob R., Gheorghe L., Iacob S., Gheorghe C., Stoicescu A., and Popescu I. – Proposal for a new risk score



associated with mortality on the waiting list for liver transplantation. 13th National Congress of Hepatology,

Bucharest, 26-27 June 2003

8. Gheorghe L., Gheorghe C., Iacob S., Iacob R., Simionov I., Vădan R., Pârvulescu I. – Overlap syndrome :

autoimmune hepatitis – primary cholestatic liver diseases. 13th National Congress of Hepatology, Bucharest, 26-27

June 2003

9. Gheorghe L., Iacob S., Hrehoreţ D. and Popescu I. – Antiviral treatment for recurrent hepatitis after liver

transplantation. 13th National Congress of Hepatology, Bucharest, 26-27 June 2003

10. Gheorghe C, Becheanu G, Iacob R, Iacob S, Mihaila C, Brescan R, Craciun E. Argon plasma coagulation

associated to pilipectomy of large sessile colonic polyps. 9th Romanian Congress of Gastroenterology, Hepatology

and Digestive Endoscopy, 24-27 September 2003, Craiova, Romania

11. Gheorghe L, Iacob S, Iacob R, Diculescu M, Gheorghe C, Constantinescu I, Ionescu A, Ciocarlan M.

Combined therapy of Peginterferon alpha-2a and Ribavirin versus Interferon alpha-2a and Ribavirin in chronic

hepatitis C – side effects and tolerability. 9th Romanian Congress of Gastroenterology, Hepatology and Digestive

Endoscopy, 24-27 September 2003, Craiova, Romania

12. Speranta Iacob. Case study. Relapse after standard interferon therapy. Difficult management of the side

effects. Symposium: The new generation of antiviral therapy in chronic hepatitis C: Pegylated interferon alpha-2a

(Pegasys), Poiana Brasov, 24 February 2004

13. R. Iacob, J.F. Quinton, F. Guillemont, I. Bancila, C. Gheorghe, S. Iacob, M. Diculescu. Esophageal

manometry abnormalities after gastric banding for morbid obesity – results of a two years prospective study. The

XXVI-th National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Timisoara, 9-11 June

2005

14. Simionov I, Vadan R, Gheorghe L, Marica C, Iacob S, Iacob R, Parvulescu I, Gheorghe C. Budd-Chiari

syndrome – prevalence, etiologic spectrum and therapeutic modalities. Scientific Meeting of Fundeni Clinical

Institute, 7-8 December 2005

15. Iacob S, Gheorghe L, Istrate A, Gheorghe C, Iacob R, Uscatescu V. Non-malignant portal vein thrombosis

in patients with hepatic cirrhosis. Scientific Meeting of Fundeni Clinical Institute, 7-8 December 2005

16. L. Gheorghe, M. Grigorescu, S. Iacob, D. Damian. Efficacy and tolerance of combined Peginterferon alfa-

2a plus Ribavirin for chronic hepatitis C in clinical practice in Romania .Seminar: Actualitati in Hepatologie si

Medicina de Laborator organizat de Centrul de Imunogenetica si Virusologie – Institutul Clinic Fundeni, Centrul

de Gastroenterologie si Hepatologie – Institutul Clinic Fundeni, Asociatia Laboratoarelor Medicale din Romania, 8

aprilie 2005, Institutul Clinic Fundeni, Bucuresti

17. Iacob S, Gheorghe L, Dima S, Bancescu O, Constantinescu I, Sarbu V, Ionescu-Targoviste C, Popescu I.

Combined liver-pancreatic islet transplantation in a patient with HCV cirrhosis and insulin dependent diabetes.

XXVII-th National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Poiana Brasov, 14-17th

June 2006

18. Gheorghe L, Iacob S, Iacob R, Gheorghe C, Popescu I. The evaluation of the liver transplantation waiting

list dynamics – results of the VIASAN project HEPASIST. XXVII-th National Symposium of Gastroenterology,

Hepatology and Digestive Endoscopy, Poiana Brasov, 14-17th June 2006

19. R. Iacob, Speranta Iacob, Simona Dima, Liana Gheorghe, I. Popescu. Therapeutic potential of

hematopoetic stem cells in liver diseases. Scientific Meeting of Fundeni Clinical Institute, 23-24 November 2006

20. Liana Gheorghe, Speranta Iacob, R. Iacob, C. Gheorghe, I. Popescu. Death prediction on the waiting list

for liver transplantation based on the serial calculation of the MELD score using the computerised HEPASIST

registry. Scientific Meeting of Fundeni Clinical Institute, 23-24 November 2006

21. Speranta Iacob, Liana Gheorghe, R. Iacob, I. Popescu. Predictive factors of survival after liver

transplantation for HCV liver cirrhosis. Scientific Meeting of Fundeni Clinical Institute, 23-24 November 2006

22. I. Popescu, Simona Dima, C. Ionescu-Targoviste, Ileana Constantinescu, Speranta Iacob. Protocol for the

pretransplant evaluation, selection of the donor and receptor and follow-up in pancreatic islet transplantation.

Scientific Meeting of Fundeni Clinical Institute, 23-24 November 2006

23. Ileana Constantinescu, Liana Gheorghe, Speranta Iacob, C. Gheorghe, R. Iacob, Doina Hrehoret, Simona



Dima, I. Popescu. Protocol of immunologic and virusologic follw-up posttransplantation for HCV liver cirrhosis.

Can be done a difference between rejection and recurrent hepatitis C? Scientific Meeting of Fundeni Clinical

Institute, 23-24 November 2006

24. I. Bancila, R. Iacob, C. Gheorghe, B. Cotruta, Dana Bucur, Daniela Voinea, Speranta Iacob, Liana

Gheorghe, D. Pitigoi, M. Manuc, M. Diculescu. Estimation of the screening and surveillance activity dynamics

based on the prospective follow-up of the data included in the COLOCANS registry. Scientific Meeting of

Fundeni Clinical Institute, 23-24 November 2006

25. L. Gheorghe, S. Iacob, B. Cotruta, R. Iacob, A. Carabelea, C. Gheorghe. Screening of cirrhotic patients

and incidence of hepatocellular carcinoma nodules. Round Table: Malignant hepatic tumors. XXVIII-th National

Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Sibiu, 14-16th June 2007

26. C. Gheorghe, B. Cotruta, V. Herlea, A. Carabelea, G. Becheanu, R. Iacob, I. Bancila, S. Iacob, L.

Gheorghe. Gastrointestinal stromal tumors: prevalence, clinical presentation and management. Oral Presentations

session – varia I. XXVIII-th National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy,

Sibiu, 14-16th June 2007

27. C. Gheorghe, B. Cotruta, R. Iacob, I. Pirvulescu, S. Iacob, I. Bancila, L. Gheorghe. Extrahepatic portal

vein thrombosis in the absence of hepatic cirrhosis: etiology and clinical presentation. Oral Presentations session –

varia II. XXVIII-th National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Sibiu, 14-16th

June 2007

28. Gheorghe L, Iacob S, Iacob R, Lupescu I, Becheanu G, Dumbrava M, Cotruta B, Grasu M, Gheorghe C.

Aspectul sonoelastografic poate prezice caracterul malign al leziunilor nodulare <3cm la un pacient cirotic – studiu

pilot. Perspective in biotehnologia romanesca sustinute prin rezultatele obtinute in cadrul Programului CEEX –

Modulul 1, BIOTECH, Cluj-Napoca, 24-26 October 2007

29. Razvan Iacob, Speranta Iacob. Importanta testelor serologice in investigarea bolilor inflamatorii si

corelatiile cu fenotipul. Al X-lea simpozion national Prof. Dr. Dimitrie Gerota Sibiu 10-12 octombrie 2007 -

Simpozion Gastroenterologie :"Locul actual al bolilor inflamatorii intestinale in patologia digestiva din Romania"

30. L. Gheorghe, S. Iacob, G. Becheanu, V. Herlea, M. Dumbrava, I. Lupescu, M. Grasu, N. Campeanu.

Valoarea elastosonografiei pentru detectia nodulilor de hepatocarcinom sub 3cm la pacientii cu ciroza hepatica.

Sesiunea stiintifica a Institutului Clinic Fundeni şi a Institutului de boli cardiovasculare “ Prof. Dr. C. C. Iliescu”,

20-21 Decembrie 2007

31. Gheorghe C, Cotruta B, Herlea V, Mihai M, Croitoru A, Becheanu G, Iacob R, Bancila I, Iacob S,

Gheorghe L. Particularitati epidemiologice, clinice si de evolutie ale tumorilor gastrointestinale stromale (GIST).


20-21 Decembrie 2007

32. Iacob R, Diculescu M, Constantinescu I, Toader A, Cotruta B, Baceanu C, Gologan S, Parvulescu I, Vadan

R, Iacob S, Gheorghe L, Gheorghe C, Preda C. ASCA and ANCA serology in Romanian IBD patients. Xth

National Congress of Gastroenterology, Hepatology and Digestive Endoscopy, Iasi 19-21 June 2008

33. Gheorghe L, Iacob S, Grigorescu M, Sporea I, Sirli R, Damian D, Gheorghe C, Iacob R. Should we treat

patients with mild hepatitis C? – Yes of course! Xth National Congress of Gastroenterology, Hepatology and

Digestive Endoscopy, Iasi 19-21 June 2008

34. Gheorghe L, Iacob S, Iacob R, Gheorghe C, Popescu I. Prediction of death on large waiting lists for liver

transplantation using MELD exceptions. Xth National Congress of Gastroenterology, Hepatology and Digestive

Endoscopy, Iasi 19-21 June 2008

35. Iacob S, Gheorghe L, Constantinescu A, Iacob R, Cerban R, Gheorghe C, Popescu I. Wilson’s disease –

type of presentation and outcomes of treatment – experience of a tertiary centre. Xth National Congress of

Gastroenterology, Hepatology and Digestive Endoscopy, Iasi 19-21 June 2008

36. Gheorghe L, Iacob S. Epidemiologia, diagnosticul si tratamentul hepatitelor cronice virale in Romania.

Simpozionul Medical Synevo 2008, 7 noiembrie 2008, Bucuresti

37. S. Iacob, L. Gheorghe, V. Herlea, G. Becheanu, D. Hrehoret, I. Popescu. Elastografia in timp real – nou

marker pentru evaluarea fibrozei hepatice la pacientii cu hepatita cronica C recurenta post transplant hepatic.




27-28 Noiembrie 2008

38. L. Gheorghe, I. Simionov, S. Iacob, R. Vadan, I. Pirvulescu. Valoarea ecografiei cu contrast in evaluarea

pacientilor cirotici cu hepatocarcinom. Sesiunea stiintifica a Institutului Clinic Fundeni şi a Institutului de boli

cardiovasculare “ Prof. Dr. C. C. Iliescu”, 27-28 Noiembrie 2008

39. S. Iacob, L. Gheorghe, M. Dumbrava, G. Becheanu. Studiu comparativ al diagnosticului hepatitei cronice

C prin elastografie in timp real versus biopsie hepatica. Sesiunea stiintifica a Institutului Clinic Fundeni şi a

Institutului de boli cardiovasculare “ Prof. Dr. C. C. Iliescu”, 27-28 Noiembrie 2008

40. L. Gheorghe, S. Iacob, M. Dumbrava, G. Becheanu, V. Herlea, I. Lupescu, I. Popescu. Progrese in

ultrasonografie: primul pas spre diagnosticul histologic virtual in tumori hepatice. Sesiunea stiintifica a Institutului

Clinic Fundeni şi a Institutului de boli cardiovasculare “ Prof. Dr. C. C. Iliescu”, 27-28 Noiembrie 2008


virus hepatitic B in Romania. The XXIXth National Symposium of Gastroenterology, Hepatology and Digestive

Endoscopy, Cluj-Napoca 18-20 June 2009

42. Iacob R, Iancu D, Barbarii L, Constantinescu I, Toader A, Cotruta B, Iacob S, Gologan S, Baceanu C,

Vadan R, Gheorghe L, Gheorghe C, Iobagiu S, Diculescu M. Model de predictie a bolii Crohn severe utilizand

profilul cde expresie mucozala a genelor inflamatorii si titrul ASCA. The XXIXth National Symposium of

Gastroenterology, Hepatology and Digestive Endoscopy, Cluj-Napoca 18-20 June 2009

43. Iacob S, Dima S, Matei E, Tanase A, Herlea V, Croitoru A, Iacob R, Gheorghe L, Gheorghe C, Popescu I.

Factori de risc ai recurentei carcinomului hepatocelular dupa tratamentul chirurgical. The XXIXth National

Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Cluj-Napoca 18-20 June 2009

44. Iacob R, Gologan S, Iancu D, Vadan R, Cotruta B, Iacob S, Preda C, Baceanu C, Pojoga C, Iobagiu S,

Gheorghe C, Gheorghe L, Barbarii L, Diculescu M. The genetics of inflammatory bowel disease in ROMANIA –

results of the IBDPROSPECT study. The XXXth National Symposium of Gastroenterology, Hepatology and

Digestive Endoscopy, Craiova, Romania, 9-11 June 2010

45. Gheorghe L, Simionov I, Vadan R, Pirvulescu I, Smira G, Iacob S, Carabelea A, Angelescu C, Gheorghe

C. Role of contrast enhanced ultrasound in the characterization of focal liver lesions: report of a series of 100

cases. The XXXth National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Craiova,

Romania, 9-11 June 2010

46. Iacob S, Cicinnati V, Dechene A, Klein C, Popescu I, Paul A, Gerken G, Beckebaum S. Role of gene

polymorphism in hepatitis C recurrence following liver transplantation. The XXXth National Symposium of

Gastroenterology, Hepatology and Digestive Endoscopy, Craiova, Romania, 9-11 June 2010

47. Iacob S, Hrehoret D, Brasoveanu V, Dorobantu B, Matei E, Alexandrescu S, Zamfir R, Romanescu D,

Gheorghe L, Popescu I. MELD and SOFT scores – predictors of mortality following liver transplantation in

Romanian liver transplant program. The XXXth National Symposium of Gastroenterology, Hepatology and

Digestive Endoscopy, Craiova, Romania, 9-11 June 2010

48. Gheorghe L, Iacob S, Csiki IE. Estimarea impactului terapiei asupra infectiei virale C in Romania. The

XXXth National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Craiova, Romania, 9-11

June 2010

49. Gheorghe L, Iacob R, Iacob S, Nastase A, Gheorghe C, Coriu D, Paslaru L. Investigation of IL28B gene

polymorphism in Romanian chronic hepatitis C patients treated with pegylated interferon and ribavirin. Genetics

in Gastrointestinal and Liver Diseases, 7-9 April 2011, Cluj-Napoca, Romania.

50. Iacob S, Iacob R, Nastase A, Coriu D, Paslaru L, Popescu I, Gheorghe L. Is it possible to use IL28B gene

polymorphism for prediction of early virological response in patients with recurrent hepatitis C following liver

transplantation? Investigation of IL28B gene polymorphism in Romanian chronic hepatitis C patients treated with

pegylated interferon and ribavirin. Genetics in Gastrointestinal and Liver Diseases, 7-9 April 2011, Cluj-Napoca,

Romania.

51. Iacob S, Gheorghe C, Iacob R, Pascu O, Gheorghe L, Goldis A, Tantau M, Dumitru E, Dobru D, Vadan R,

Saftoiu A, Bancila I, Pirvulescu I, Tugui L, Diculescu M. Prevalence of malnutrition in patients admitted in tertiary



gastroenterology centers from Romania: a multicentric study.The XIIth National Symposium of Clinical Nutrition,

11-13 November 2011, Poiana Brasov, Romania.

52. Iacob S, Iacob R, Nastase A, Gheorghe C, Coriu D, Paslaru L, Gheorghe L. The association of IL28B CC

genotype and mild fibrosis – the favorable baseline profile predicting SVR in naive infected patients. VIIth

“Academician Nicolae Cajal” Symposium. 28-31 March 2012, Bucharest, Romania.

53. Iacob R, Iacob S, Nastase A, Vagu C, Ene AM, Constantinescu A, Anghel D, Banica C, Paslaru L, Coriu

D, Dima S, Ionica E, Gheorghe L. The His1069Gln mutation in the ATP7B gene, in Romanian patients with

Wilson’s Disease, referred to a tertiary gastroenterology Center. VIIth “Academician Nicolae Cajal” Symposium.

28-31 March 2012, Bucharest, Romania.

54. Iacob S. Experienta Institutului Clinic Fundeni in transplantul hepatic pentru ciroza hepatica C: analiza

factorilor ce determina outcome-ul. Al VIII-lea Congres Romtransplant, 26-29 Septembrie, Bucuresti, Romania

55. Iacob S, Vagu C, Iacob R, Nastase A,Paslaru L, Popescu I, Ruta S, Gheorghe L. Recipient IL28B gene

polymorphism and sustained viral response in Romanian patients with recurrent hepatitis C following liver

transplantation. XXXIIIrd Romanian National Congress of Gastroenterology and Hepatology, 12-15 June 2013,

Timisoara, Romania.

56. R Iacob, C Vagu, A Năstase, S Iacob, M Grigorie, V Herlea, A Croitoru, S Dima, C Gheorghe, L

Gheorghe, M Ott, I Popescu. Quantitative gene expression of liver enriched transcription factors for prediction of

tumor recurrence after curative treatment of hepatocellular carcinoma. XXXIIIrd Romanian National Congress of

Gastroenterology and Hepatology, 12-15 June 2013, Timisoara, Romania.

57. Tugui L, Iacob S, Gheorghe L, Preda CM, Cerban R, Becheanu G, Dumbrava M, Diculescu M.

Treatment of chronic hepatitis delta virus with Peg-Interferon. XXXIIIrd Romanian National Congress of

Gastroenterology and Hepatology, 12-15 June 2013, Timisoara, Romania.

58. Gheorghe L, Iacob S, Caruntu F, Simionov I, Motoc A, Arama V, Preotescu L, Stefan I, Goldis A. A week

8 model predicting early virologic response (EVR) and futility of boceprevir (BOC), PegInterferon (PEG) and

ribavirin (RBV) regimen. XXXIIIrd Romanian National Congress of Gastroenterology and Hepatology, 12-15

June 2013, Timisoara, Romania.

59. Gheorghe L, Iacob S. Profilul pacientului care beneficiaza e terapiile locoregionale – caz clinic. Simpozion

Nexavar “Cercul Sperantei”, 23-25 august 2013

60. Iacob S. Discutii cazuri clinice, sesiune cu vot electronic. Simpozion Nexavar “Cercul Sperantei”, 23-25

august 2013

61. Iacob R, Vagu C, Nastase A, Iacob S, Botea F, Grigorie R, Hrehoret D, Herlea V. Croitoru A, Dima S,

Gheorghe L, Gheorghe C, Popescu I. Expression profile of stem/progenitor cells specific genes in hepatocellular

carcinoma and potential prognostic significance. The XXXIVth National Symposium of Gastroenterology,

Hepatology and Digestive Endoscopy, Oradea, Romania, 11-14 June 2014

62. Cerban R, Gheorghe L, Iacob S, Smira G, Pietrareanu C, Iacob R, Ester C, Gheorghe C. Clostridium

difficile infection, a poor outcome predictor in patients with cirrhosis. A tertiary liver transplant center perspective

from Romania. The XXXIVth National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy,

Oradea, Romania, 11-14 June 2014

63. Gheorghe L, Iacob S, Simionov I, Caruntu F, Motoc A, Arama V, Goldis A, Brisc C. A week 8 stopping

model for real life genotype 1 patients with advanced fibrosis treated with boceprevir-based triple regimen. The

XXXIVth National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Oradea, Romania, 11-

14 June 2014

64. Iacob S, Ester C, Popescu I, Gheorghe L. Risk factors for death in cirrhotic patients with non-malignant

portal vein thrombosis on the waiting list for liver transplantation. The XXXIVth National Symposium of

Gastroenterology, Hepatology and Digestive Endoscopy, Oradea, Romania, 11-14 June 2014


Popescu I. Predictors of short-term post-liver transplant mortality in the Romanian Transplant Program. The

XXXIVth National Symposium of Gastroenterology, Hepatology and Digestive Endoscopy, Oradea, Romania, 11-

14 June 2014



66. Iacob R, Vagu C, Nastase A, Ghetea L, Iacob S, Grigorie R, Botea F, Herlea V, Croitoru A, Gheorghe C,

Popescu I, Gheorghe L. Recurrence risk stratification of patients with hepatocellular carcinoma following a

potentially curative treatment using gene expression of liver stem/progenitor cells specific markers. The XXXVth

National Congress of Gastroenterology, Hepatology and Digestive Endoscopy, Iasi, Romania, 11-13 June 2015

67. Iacob S, Iacob R, Vagu C, Gheorghe C, Popescu I, Gheorghe L. RS199508964 deletion in exon 6 of IRF5

gene is associated with IL28B gene SNP RS12980275 and predicts suustained virological response in patients

with recurrent hepatitis C following liver transplantation. The XXXVth National Congress of Gastroenterology,

Hepatology and Digestive Endoscopy, Iasi, Romania, 11-13 June 2015

68. Iacob R, Iacob S, Nastase A, Ilie V, Sorop A, Florea R, Herlea V, Croitoru A, Dima S, Gheorghe C,

Gheorghe L, Ott M, Popescu I. Prognostic and therapeutic significance of HNF4alpha expression in hepatocellular

carcinoma. Xth “Academician Nicolae Cajal” Symposium. 1-4 April 2015, Bucharest, Romania.

69. Iacob S, Iacob R, Vagu C, Ruta S, Gheorghe C, Paslaru L, Popescu I, Gheorghe L. Deletia rs199508964

din exonul 6 al genei IRF5 se coreleaza cu polimorfismul genei Il28B rs12980275 si prezice raspunsul virusologic

sustinut la pacientii cu hepatita recurenta C post-transplant hepatic. Xth “Academician Nicolae Cajal” Symposium,

1-4 April 2015, Bucharest, Romania

70. Gheorghe L, Iacob S. Prevalence of mixed cryoglobulinemia in 150 patients with chronic hepatitis C

treated with ombitasvir/paritaprevir/ritonavir+dasabuvir+ribavirin. The XXXVIth National Congress of

Gastroenterology, Hepatology and Digestive Endoscopy, Cluj-Napoca, Romania, 8-11 June 2016

71. Iacob R, Vagu C, Nastase A, Ghetea L, Iacob S, Botea F, Herlea V, Croitoru A, Dima S, Gheorghe C,

Popescu I, Ott M, Gheorghe L. Hepatocyte reprogramming in a stem-cell-like phenotype. A potential mechanism

of hepatocarcinogenesis. The XXXVIth National Congress of Gastroenterology, Hepatology and Digestive

Endoscopy, Cluj-Napoca, Romania, 8-11 June 2016

72. Iacob S, Popescu I, Gheorghe L. 100% virological response with interferon-free regimens and significant

improvement of liver stiffness in pre- and post-transplant patients with chronic C hepatitis. The XXXVIth National

Congress of Gastroenterology, Hepatology and Digestive Endoscopy, Cluj-Napoca, Romania, 8-11 June 2016

73. Iacob S, Iacob R, Cerban R, Gheorghe C, Gheorghe L. Staging of hepatocellular carcinoma in patients

with liver cirrhosis enrolled in a screening program. The XXXVIth National Congress of Gastroenterology,

Hepatology and Digestive Endoscopy, Cluj-Napoca, Romania, 8-11 June 2016

74. Lita M, Iacob S, Ester C, Gheorghe C, Gheorghe L. Primary sclerosing cholangitis, clincal characteristics,

low incidence of the association with inflammatory bowel disease and low complication rates. The XXXVIth

National Congress of Gastroenterology, Hepatology and Digestive Endoscopy, Cluj-Napoca, Romania, 8-11 June

2016

75. Iacob R, Becheanu G, Herlea V, Pechianu C, Dumbrava M, Iacob S, Vagu C, Nastase A, Ghetea L,

Gheorghe L, Popescu I. Hepatocyte telomerase expression in chronic liver disease and primary liver tumors –

arguments for hepatocyte reprogramming. Al 11-lea Simpozion Academician Nicolae Cajal, 17-19 martie 2016,

Bucuresti

76. Iacob S, Popescu I, Gheorghe L. 100% SVR 12 with interferon-free regimens in both pre and

posttransplant patients with hepatitis C although on treatment viral kinetics differ between cirrhosis and LT

recipients. Al 11-lea Simpozion Academician Nicolae Cajal, 17-19 martie 2016, Bucuresti

77. Speranta Iacob. Prezentare caz clinic III. Atelierul “Ridicand stacheta in carcinomul hepatocelular”. Al

treilea congres national de oncologie medicala si radioterapie al federatiei societatilor romane de cancer, 3-5

noiembrie 2016, Bucuresti, Romania

78. R. Vadan, S. Iacob, B. Stoica, S. Ichim, M. Lita, C. Cijevschi, A. Trifan, D. Dobru, E. Dumitru, M. Tantau,

C. Brisc, M. Diculescu, C. Gheorghe, L. Gheorghe. Nutrition risk profile in a university hospital population. Al

XXVII-lea Simpozion National de Nutritie Clinica (cu participare international), 4-6 Noiembrie 2016, Poiana

Brasov, Romania

79. Gheorghe L, Iacob S. Terapia antivirala in hepatita C si riscul carcinomului hepatocelular. Conferinta

Tratamente Inovative in Oncologie – Editia a IIIa – Analiza moleculara si terapia individualizata in cancer, 3

martie 2017, Bucuresti, Romania



80. Iacob S, Popescu I, Gheorghe L. Dynamic of liver stiffness and serum markers of fibrosis in HCV liver

transplant recipients with SVR following interferon free treatment.The Symposium Academician Nicolae Cajal of

the Academy of Medical Sciences, 30March-1 April 2017

81. Iacob R, Popa C, Herlea V, Nastase A, Ghetea L, Iacob S, Botea F, Dima S, Croitoru A, Gheorghe C,

Gheorghe L, Ott M, Popescu I. Expression of liver stem/progenitor cell specific genes in hepatocellular carcinoma

occurring on liver cirrhosis: the significance reprogramming factors OCT4 ad SOX2. The Symposium

Academician Nicolae Cajal of the Academy of Medical Sciences, 30March-1 April 2017

82. Iacob Speranta. De novo HCC following 3D antiviral therapy and SVR in a patient with HCV genotype

1b liver cirrhosis. Workshop 1: Management of chronic hepatitis C in DAAs era. 4th UpDate on Hepatology

Course, Bucharst 2017, Romania

83. Dima S, Nastase A, Sorop A, Tica V, Florea R, Ilie V, Bacalbasa N, Alexandrescu S, Cucu D, Iacob R,

Iacob S, Herlea V, Popescu I, Duda D. VEGF si EGF-C circulanti, potentiali biomarkeri prognostici pentru

pacientii cu hepatocarcinom operati. Workshop “ Stratificarea pacientilor cu carcinom hepatocelular prin

identificarea unor markeri neinvazivi” (Proiect HEPMARK), Universitatea Titu Maiorescu din Bucuresti, 28

aprilie 2017

84. Iacob S, Pirvulescu I, Iacob R, Gheorghe C and Gheorghe L. Evaluation with transient elastography and

controlled attenuation parameter of a cohort of patients with CLD admitted in a hepatology tertiary center.

Al 37-lea Congres de Gastroenterologie, Hepatologie și Endoscopie Digestivă, Bucuresti 22-24 iunie

2017

85. Iacob S, Gheorghe L, Cijevschi C, Trifan A, Stanciu C, Sporea I, Sirli R, Curescu M, Diculescu M,

Sandulescu L, Alexandrescu L, Goldis A, Brisc C, Simionov I, Vadan R, Pirvulescu I, Rogoveanu I,

Pietrareanu C, Seicean A, Iacob R, Gheorghe C. Model to predict clinically significant portal hypertension

in patients with HCV liver cirrhosis following SVR post-therapy with Ombitasvir/Paritaprevir/ritonavir

and Dasabuvir. Al 37-lea Congres de Gastroenterologie, Hepatologie și Endoscopie Digestivă, Bucuresti

22-24 iunie 2017


by means of transient elastography in patients with HCV liver cirrhosis undergoing interferon-free

treatment. Al 37-lea Congres de Gastroenterologie, Hepatologie și Endoscopie Digestivă, Bucuresti 22-24

iunie 2017

87. Popescu A, Lupusoru R, Sirli R, Danila M, Gheorghe L, Seicean A, Trifan A, Curescu M, Goldis A,

Sandulescu L, Cijevschi C, Stanciu C, Brisc C, Iacob S, Sporea I. In how many patients will we

misdiagnose esophageal varices by using the Baveno VI criteria? Al 37-lea Congres de Gastroenterologie,

Hepatologie și Endoscopie Digestivă, Bucuresti 22-24 iunie 2017

88. Iacob R, Popa C, Herlea V, Becheanu G, Nastase A, Ghetea I, Iacob S, Botea F, Dima S, Croitoru A,

Gheorghe C, Ott M, POpescu I, Gheorghe L. The significance of OCT4 and SOX2 reprogramming

factors expression in hepatocellular carcinoma occurring on liver cirrhosis. Al 37-lea Congres de

Gastroenterologie, Hepatologie și Endoscopie Digestivă, Bucuresti 22-24 iunie 2017 (OP11)

89. Stoica B, Saizu I, Cojocaru M, Dimitriu A, Stefan A, Lupu A, Iacob S, vadan R, Gologan S, Gheorghe L,

Gheorghe C, Diculescu M, Iacob R. Al 37-lea Congres de Gastroenterologie, Hepatologie și Endoscopie

Digestivă, Bucuresti 22-24 iunie 2017 (OP35)

90. Iacob S, Pietrareanu C, Popescu I, Gheorghe L. Efficacy, safety and noninvasive monitoring of fibrosis in

patients with recurrent hepatitis C treated with direct acting antivirals. Al Xlea Congres RomTransplant,

Bucuresti, 29 Martie 2018

91. Brasoveanu V, Hrehoret D, Botea F, Dorobantu B, Alexandrescu S, Grigorie M, Matei E, Zamfir R,

….Gheorghe L, Iacob S, Pietrareanu C….Popescu I.Transplantul hepatic de la donator in viata. Al Xlea

Congres RomTransplant, Bucuresti, 29 Martie 2018

92. Popescu I, Ionescu M, Brasoveanu V, Hrehoret D, Copca N, Lupascu C.... Gheorghe L, Iacob S,



Pietrareanu C….Sasalovici D. Programul de transplant hepatic din Romania: trecut, przent, viitor. Al Xlea

Congres RomTransplant, Bucuresti, 29 Martie 2018

93. Iacob S, Ester C, Cerban R, Pietrareanu C, Iacob R, Gheorghe C, Gheorghe L. Factori predicivi pentru

regresia cirozei hepatice la un an dupa eradicarea VHC. In cadrul Mesei Rotunde “Lucrari originale”. Al

38-lea Congres National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, 24-26 Mai 2018,

Craiova, Romania (Lucrare premiata – Premiul II)

94. Cerban R, Ester C, Iacob S, Paslaru L, Dumitru R, Grasu M, Constantin G, Gheorghe C, Gheorghe L.

Factori predictivi pt raspunsul complet si recurenta la pacientii cu carcinom hepatocelular tratati prin

chemoembolizare transarteriala. In cadrul Mesei Rotunde “Lucrari originale”. Al 38-lea Congres National

de Gastroenterologie, Hepatologie si Endoscopie Digestiva, 24-26 Mai 2018, Craiova, Romania

95. Ghioca M, Iacob S, Ester C, Pietrareanu C, Cerban R, Iacob R, Gheorghe C, Gheorghe L. Prognosticul pe

termen mediu la pacientii cu colangita biliara primitiva. Zilele Institutului Clinic Fundeni 2018, 3-6

Octombrie 2018

96. Cerban R, Ester C, Iacob S, Pietrareanu C, Ghioca M, Ichim S, Constantin G, Paslaru L, Gheorghe L.

Factori predictivi ai recurentei si supravietuirii la pacientii tratati prin chemoembolizare. Zilele Institutului

Clinic Fundeni 2018, 3-6 Octombrie 2018

97. Iacob S, Ester C, Cerban R, Pietrareanu C, Iacob R, Lita M, Gheorghe C, Gheorghe L. Factori predictivi

pentru regresia fibrozei hepatice dupa obtinerea SVR la pacientii tratati cu DAA. Zilele Institutului Clinic

Fundeni 2018, 3-6 Octombrie 2018

98. Ester C, Cerban R, Iacob S, Pietrareanu C, Ghioca M, Ichim S, Constantin G, Paslaru L, Ruta S, Gheorghe

L. Noi biomarkeri pentru detectia precoce a NAFLD si a complicatiilor acesteia la pacientii transplantati

hepatic. Zilele Institutului Clinic Fundeni 2018, 3-6 Octombrie 2018

99. Popescu I, Ionescu M, ...Gheorghe L, Iacob S, Pietrareanu C...Sasalovici D. Programul de transplant

hepatic al IC Fundeni. Zilele Institutului Clinic Fundeni 2018, 3-6 Octombrie 2018

100. Brasoveanu V, Hrehoret D, ... Gheorghe L, Iacob S, Pietrareanu C..., Popescu I. Transplantul

hepatic de la donator in viata in IC Fundeni. Zilele Institutului Clinic Fundeni 2018, 3-6 Octombrie 2018

101. Stoica Bianca, Razvan Iacob, Speranta Iacob, Adina Croitoru, Cristina Radu, Cristian Gheorghe.

Real life results of first line palliative chemotherapy in pancreatic ductal adenocarcinoma. Al 39-lea

Congres National de Gastroenterologie, Hepatologie si Oncologie Digestiva, 6-8 Iunie 2019, Timisoara,

Romania

102. Ester Carmen, Razvan Cerban, Razvan Iacob, Speranta Iacob, Andrei Sorop, Lorand Savu,

Mihaela Ghioca, Georgiana Constantin, Liliana Pislaru, Simona Ruta, Irinel Popescu, Liana Gheorghe.

Predictors for metabolic syndrome and cardiovascular risk in liver transplant recipients – a single center

experience. Al 39-lea Congres National de Gastroenterologie, Hepatologie si Oncologie Digestiva, 6-8

Iunie 2019, Timisoara, Romania

103. S. Iacob, M. Onica, C. Pietrareanu, C. Ester, R. Cerban, R. Iacob, C. Gheorghe, I. Popescu, L.

Gheorghe. Metabolic and renal function evaluation after HCV cure in LT recipients. Al 39-lea Congres

National de Gastroenterologie, Hepatologie si Oncologie Digestiva, 6-8 Iunie 2019, Timisoara, Romania

104. Speranța Iacob, Mihaela Ghioca, Dana Tomescu, Gabriela Droc, Vlad Brașoveanu, Doina

Hrehoreț, Corina Pietrareanu, Răzvan Iacob, Cristian Gheorghe, Irinel Popescu, Liana Gheorghe. Factorii

asociați cu supraviețuirea pacienților cu insuficiență hepatică cronică acutizată pre- și post-transplant.

Zilele Institutului Clinic Fundeni 2019, Bucuresti, 08 – 10 IULIE 2019

105. Carmen Ester, Răzvan Cerban, Răzvan Iacob, Speranța Iacob, Andrei Sorop, Lorand Savu,

Mihaela Lita, Georgiana Constantin, Liliana Pâslaru, Camelia Grancea, Simona Ruță, Irinel Popescu,



Liana Gheorghe. Factori predictivi pentru steatohepatita recurentă șau de novo la pacienții transplantați

hepatic - experiența unui centru de volum mare. Zilele Institutului Clinic Fundeni 2019, Bucuresti, 08 – 10

IULIE 2019

106. Mihaela Olita, Speranța Iacob, Daniela Anghel, Ecaterina Scărlătescu, Mihai Popescu, Mara

Ștefan, Mădalina Băluță, Adelina Vasile, Marian Tudoroiu, Dana Tomescu. Insuficiența hepatică acută post

partum – o dificultate diagnostică și terapeutică. Zilele Institutului Clinic Fundeni 2019, Bucuresti, 08 – 10

IULIE 2019

107. Vladislav Brașoveanu, Doina Hrehoreț, Bogdan Dorobantu, ..., Liana Gheorghe, Speranța Iacob,

Corina Pietrareanu, ....,Irinel Popescu. Transplantul de ficat de la donator viu. Zilele Institutului Clinic

Fundeni 2019, Bucuresti, 08 – 10 IULIE 2019

108. Vladislav Brașoveanu, Doina Hrehoreț, Mihnea Ionescu, ....Liana Gheorghe, Speranța Iacob,

Corina Pietrareanu, .....,Irinel Popescu. Zilele Institutului Clinic Fundeni 2019, Bucuresti, 08 – 10 IULIE

2019

109. Liana Gheorghe, Speranța Iacob, Camelia Cojocaru, Laura Huiban, Roxana Nemteanu, Irina

Girleanu, Victor Baldea, Răzvan Iacob, Anca Trifan, Ioan Sporea, Cristian Gheorghe. Hep C Alert -

rezultatele preliminare ale campaniei de micro-eliminare inițiată de Societatea Română de

Gastroenterologie și Hepatologie. Zilele Institutului Clinic Fundeni 2019, Bucuresti, 08 – 10 IULIE 2019

110. Speranța Iacob, Mirela Onica, Corina Pietrareanu, Carmen Ester, Răzvan Cerban, Răzvan Iacob,

Cristian Gheorghe, Irinel Popescu, Liana Gheorghe. Eradicarea VHC post-DAA ameliorează funcția

hepatică, fară a avea impact benefic asupra manifestărilor extrahepatice la pacienții cu hepatită cronică C

recurentă posttransplant. Zilele Institutului Clinic Fundeni 2019, Bucuresti, 08 – 10 IULIE 2019

111. Liana Gheorghe, Speranța Iacob, Mugur Grasu, Cătalina Mihai, Cristina Cijevschi, Corina

Pietrareanu, Roxana Vadan, Iulia Simionov, Iuliana Pirvulescu, Răzvan Iacob, Ioana Lupescu, Cristian

Gheorghe. Tratamentul cu antivirale cu acțiune directă nu crește riscul apariției hepatocarcinomului la

pacientul cu ciroză hepatică VHC eradicată. Zilele Institutului Clinic Fundeni 2019, Bucuresti, 08 – 10

IULIE 2019

112. Răzvan Cerban, Carmen Ester, Speranța Iacob, Liliana Pâslaru, Radu Dumitru, Mugur Grasu,

Constantin Georgiana. Evaluarea utilității alfa-fetoproteinei și des-gamma-carboxiprotrombinei pentru

diagnosticul hepatocarcinomului în variate stadii la pacienții evaluați într-un centru de transplant hepatic.

Zilele Institutului Clinic Fundeni 2019, Bucuresti, 08 – 10 IULIE 2019

C.Prezentari sub forma de poster - 383

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